- June 03, 2026
New AI tool maps hidden geography of gene activity
- May 27, 2026Source: Miami Herald
45% of the nation’s tap water contains chemicals that may be harmful to humans, experts warn
- March 31, 2026
What experts wish you knew about colon cancer
- March 19, 2026Source: NPR
FDA backs off on stricter tanning bed rules
Cancer
More people today die from cancer than from almost any other cause in the world. The challenges posed by cancer are immense and top scientists at the Yale School of Public Health are committed to reducing its toll.
The departments of Chronic Disease Epidemiology, Biostatistics and Health Policy and Management are heavily focused on a wide variety of cancer-related research, and the Department of Environmental Health Sciences is renowned for novel approaches to the study of how environmental exposures affect health outcomes. From key partnerships with the Yale Cancer Center to collaborative efforts locally and globally, YSPH scientists are taking significant steps toward preventing and treating a wide range of cancers. Today, research in cancer and other chronic diseases encompasses interdisciplinary teams committed to understanding cancer causation and etiology, prevention, screening and early detection, risk factors, environmental exposures, social determinants of health and survival.
A variety of technologies and approaches are used to detect mechanisms and characteristics of the many different types of cancer, including genomics, metabolomics, social and behavioral effects, evolutionary biology, biostatistical methodology and study design, and outcomes research.
The Yale School of Public Health maintains biospecimens and data from thousands of individuals in more than a dozen studies that can be made applied to future research. It also has partnerships with numerous international cancer researchers, and is the home of leading experts in clinical trial design and data management, and genomic and metabolic centers.
Recent Publications
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- Individualized Treatment Effect Inference of Head and Neck Cancer with Multimodal Data.Wei Y, Li Z, Woo J, Ouyang J, El Fakhri G, Liu X. APSIPA Trans Signal Inf Process. 2026 Dec 14; 2026 May 1. PMID: 42125301.
- Migration-Associated Variation in Gastric Cancer Risk in the United States: Implications for Risk Stratification.Hyun CS, Wang R, Hong SH, Zhang X, Shin JI. Int J Cancer. 2026 Jun 7; 2026 Jun 7. PMID: 42252557.
- Decreases in Human Papillomavirus Vaccine Types 16 and 18 in Cervical Precancers: HPV-IMPACT, 2008 to 2019.Stefanos R, Gargano JW, Niccolai LM, Castilho JL, Park IU, Bostick EA, Ehlers S, Blankenship S, Brackney MM, Chan K, Kurtz R, Whitney E, Moritz RE, Vigar MK, Querec TD, Unger ER, Markowitz LE. Cancer Epidemiol Biomarkers Prev. 2026 Jun 2. PMID: 42089801.
- Clinical Instruments Assessing Harms and Benefits of Long-Term Opioid Therapy for Chronic Pain: A Scoping Review.Grant AD, Ali M, Cheng A, Funaro MC, Black AC, Esserman D, DeBar LL, Edmond S, Becker WC. J Gen Intern Med. 2026 Jun 1; 2026 Jun 1. PMID: 42225871.
- Real-world Clinical Outcomes of Ivermectin and Mebendazole in Cancer Patients: Results from a Prospective Observational Cohort.Hulscher N, Victory K, Thorp JA, Pinsky D, Diaz-Villalobos A, Gillooly P, Coulson F, Annazone M, Radesi C, Brooks J, McCULLOUGH PA, Risch H. Anticancer Res. 2026 Jun. PMID: 42203321.
- Long-read nanopore shotgun metagenomic DNA sequencing for river biodiversity, wildlife, pollution, and environmental health monitoring.Nousias O, Duffy FG, Duffy IJ, McCauley M, Whilde J, Duffy DJ. NAR Genom Bioinform. 2026 Jun; 2026 Apr 24. PMID: 42038409.
- Dyspepsia Care as a Missed Gateway to Gastric Cancer Prevention in High-Risk U.S. Populations.Hyun C, Oh SS, Hong SH, Kumar S, Shin JI. J Immigr Minor Health. 2026 Jun; 2026 Feb 23. PMID: 41729425.
- Changes in Use, Cost, and Value of Breast Cancer Screening Among Older Women in the US.Richman I, Long JB, Lindsay ME, Fendrick AM, Kyanko K, Gross CP. J Gen Intern Med. 2026 Jun; 2025 Sep 23. PMID: 40987968.
- Baseline predictors associated with successful weight loss among breast cancer survivors in the Lifestyle, Exercise, and Nutrition (LEAN) study.Hoobler R, Puklin LS, Harrigan M, Cartmel B, Li FY, Sanft T, Ferrucci LM, Irwin ML, Playdon MC. J Cancer Surviv. 2026 Jun; 2024 Nov 11. PMID: 39528779.
- Multi-ancestry transcriptome-wide association studies uncover insights into breast cancer genetics and biology.Ping J, Jia G, Cai Q, Guo X, Wang J, Tao R, Li B, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Park B, Press MF, Sanderson M, Sandler DP, Yao S, Zheng Y, Ahearn T, Brewster AM, Falusi A, Hennis AJM, Ito H, Kubo M, Lee ES, Makumbi T, Mapoko BSE, Noh DY, O'Brien KM, Ojengbede O, Olshan AF, Park MH, Reid S, Yamaji T, Zirpoli G, Butler EN, Huang M, Low SK, Obafunwa J, Weinberg CR, Zhang H, Zhao H, Ambrosone CB, Cote ML, Huo D, Haiman CA, Kang D, Palmer JR, Troester MA, Shu XO, Long J, Zheng W. Nat Commun. 2026 May 30; 2026 May 30. PMID: 42218145.
- Migration-Informed Cancer Equity: A Global Perspective.Hyun CS. Ann Glob Health. 2026; 2026 May 26. PMID: 42221421.
- Management and outcomes of patients with liver cancer in China and the United States.Xu M, Geng Q, Shan T, Liu M, Chen J, Liu M, Han B, Xia C, Ran X, Sun K, Wang S, Shen Y, Chen R, Li L, Zhao H, Chen W, Lu L, Zhang Y, Zeng H. Chin Med J (Engl). 2026 May 20; 2026 Apr 1. PMID: 41922917.
- No-cost envelope modification improves fecal immunochemical test laboratory acceptance in a US Veterans Affairs colorectal cancer screening trial.Dominitz JA, Robertson DJ, Miller S, Beed A, Boardman K, Del Curto B, Gupta S, Imperiale TF, Larson MF, Lieberman DA, Rosa S, Shaukat A, Sultan S, Tapia D, Kyriakides TC. J Med Screen. 2026 May 19; 2026 May 19. PMID: 42154016.
- Adherence to pro-vegetarian dietary patterns and gastric cancer risk: a pooled analysis of the StoP Consortium.Oncina-Cánovas A, Torres-Collado L, García-de-la-Hera M, González-Palacios S, Ojeda-Belokon C, Negri E, Pelucchi C, Lagiou A, Lagiou P, Lunet N, Morais S, Martin V, Castaño-Vinyals G, López-Carrillo L, Hernández-Ramírez RU, Camargo MC, Curado MP, Zhang ZF, La Vecchia C, Boffetta P, Vioque J. Gastric Cancer. 2026 May 14; 2026 May 14. PMID: 42133181.
- Risk of late recurrence of colorectal and breast cancer among older long-term cancer survivors.Yasin F, Westvold SJ, Long JB, Hyslop T, Cecchini M, Leeds I, Silber A, Wang SY, Spees L, Forman R, Kwaramba T, Taylor M, Gross CP, Dinan MA. JNCI Cancer Spectr. 2026 May 9. PMID: 41499446.
- Glycosite mapping and in situ mass spectrometry imaging of MUC2 glycopeptides via on-slide mucinase digestion.Lowery SC, Ribi MK, Chongsaritsinsuk J, Tran IP, Grimsley G, Stubler R, Mahoney KE, Lucas TM, Charkoftaki G, Santos-Neto A, Varki N, Vasiliou V, Angelo M, Drake RR, Malaker SA. Nat Commun. 2026 May 7; 2026 May 7. PMID: 42098121.
- Prostate-Specific Membrane Antigen Imaging and Initial Treatment for Prostate Cancer.Leapman MS, Rothen J, Long JB, Kim IE, Mitchell AE, Yu JB, Dinan MA, Gross CP, Ma X. JAMA Oncol. 2026 May 7; 2026 May 7. PMID: 42096231.
- AI-driven integration of genomic and exposome data for cancer risk: the combined risk score (CRS).Sarigiannis D, Boukovinas I, Kaparelou M, Dimopoulos AM, Psaltopoulou T, Pienta KJ, Anesti O, Karakitsios S. Hum Genomics. 2026 May 4; 2026 May 4. PMID: 42083001.
- Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade.Talty R, Brooks VT, McGeary MK, Milette S, Zheng S, Flem-Karlsen K, Daniels A, Deshmukh M, Park K, Caraccio W, Yan H, Echeandia-Francis C, McNamara M, Hong S, Kirwin DS, Olino K, Johnson CH, Bosenberg M, Micevic G, Roy SF. Mol Cancer Ther. 2026 May 4. PMID: 41423587.
- Medicare Insurance Type and Broad Genomic Profiling in Metastatic Cancer.Chow RD, Rothen J, Long JB, Soulos PR, Wang X, Mamtani R, Ma S, Kunst N, Dinan MA, Gross CP. JAMA Netw Open. 2026 May 1; 2026 May 1. PMID: 42201732.
- Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations.Koller D, He J, Løkhammer S, Aranda S, Qiu D, Davtian D, Chen Q, Xu Z, Mao Z, Friligkou E, Karaca S, Cormand B, Flores I, Altmäe S, Mitjans M, Cabrera-Mendoza B, Polimanti R. Nat Genet. 2026 May; 2026 Apr 29. PMID: 42056605.
- Robust Heterogeneity Adjustment for Gaussian Graphical Model With Latent Variables.Li L, Li R, Ma S, Zhang Q. Stat Med. 2026 May. PMID: 42053355.
- Eligibility criteria for cancer drug trials in adult patients: Evidence from China, 2013-2021.Ma Z, Zhang Y, Chen D, Fu M, Han K, Zhang Y, Ross JS, Shi L, An Z, Guan X. Cancer. 2026 May 1. PMID: 42046201.
- Illustrating Implications of Misaligned Causal Questions and Statistics in Settings With Competing Events and Interest in Treatment Mechanisms.Kawahara T, McGrath S, Young JG. Stat Med. 2026 May. PMID: 42031001.
- Catabolism of extracellular glutathione supplies cysteine to support tumours.Hecht F, Zocchi M, Tuttle ET, Ward NP, Alimohammadi F, Khan AA, Gomes VC, Smith B, Twardowski JJ, Mills BN, Welle KA, Ghaemmaghami S, Zhou Z, Gan Y, Kang YP, Cazarin J, Soares ZG, Ozgurses ME, Zhao H, Sheehan C, Cognet G, Munger LD, Trivedi D, Asantewaa G, Blick-Nitko SK, Zoeller JJ, Chen Y, Vasiliou V, Turner BM, Mello SS, Altman BJ, Muir A, Coloff JL, Munger J, DeNicola GM, Harris IS. Nature. 2026 May; 2026 Mar 18. PMID: 41851454.
- Emerging biomarkers in melanoma: Bridging molecular discovery and precision oncology.Xu S, Huang Z, Li Y, Lu L, Ma W. Cancer Lett. 2026 May 1; 2026 Feb 22. PMID: 41734832.
- The impact of genetic and environmental risk factors on adverse liver outcomes.Zhang X, Zhao L, Campbell PT, Chen Y, Fang A, Liu Z, Li X, Yang W, Fan J, Petrick JL, McGlynn KA, Lai M, Zhang X. Int J Cancer. 2026 May 1; 2025 Dec 4. PMID: 41345374.
- Challenges in the return of molecular tumor profiling results.Lenz HJ, Craig DW, Johnson KC, Verhaak R, Bhattacharyya O, Davis B, Wesley C, Byron SA, Willman C, Kelley L, Claus EB, Trent J, Culver JO, Gray SW, Church AJ. J Natl Cancer Inst. 2026 May 1. PMID: 40929086.
- Mutational signature-based classification uncovers emerging oral cancer subtypes with distinct molecular patterns.Deneuve S, Fervers B, Bruno JS, Bach E, Senkin S, Goldman-Lévy G, Carreira C, Laklouk I, Hu R, Bouaoun L, Pérol O, Chavanel B, Lu L, Lozar T, Gheit T, Lambert PF, Coste I, Renno T, Zavadil J, Virard F. Int J Oral Sci. 2026 Apr 24; 2026 Apr 24. PMID: 42031720.
- Novel Genetic Risk Loci for Pancreatic Ductal Adenocarcinoma Identified in a Genome-wide Study of African Ancestry Individuals.Vergara C, Ni Z, Zhong J, McKean D, Connelly KE, Antwi SO, Arslan AA, Bracci PM, Du M, Gallinger S, Genkinger J, Haiman CA, Hassan M, Hung RJ, Huff C, Kooperberg C, Kastrinos F, LeMarchand L, Lee W, Lynch SM, Moore SC, Oberg AL, Park MA, Permuth JB, Risch HA, Scheet P, Schwartz A, Shu XO, Stolzenberg-Solomon RZ, Wolpin BM, Zheng W, Albanes D, Andreotti G, Bamlet WR, Beane-Freeman L, Berndt SI, Brennan P, Buring JE, Cabrera-Castro N, Campa D, Canzian F, Chanock SJ, Chen Y, Chung CC, Eliassen AH, Gaziano JM, Giles GG, Giovannucci EL, Goggins M, Goodman PJ, Hicks B, Hutchinson A, Jones MR, Katzke V, Kogevinas M, Kurtz RC, Laheru D, Lee IM, Malats N, Milne R, Mucci L, Neale RE, Orlow I, Patel AV, Peruchet L, Peters U, Porta M, Rabe KG, Real FX, Ricceri F, Rothman N, Sesso HD, Setiawan VW, Silverman D, Southey MC, Stampfer MJ, Tobias GS, Um C, Visvanathan K, Wactawski-Wende J, Wentzensen N, Willett WC, Yu H, Kraft P, Duggal P, Amundadottir LT, Klein AP. medRxiv. 2026 Apr 22; 2026 Apr 22. PMID: 42078392.
- Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers.Shi M, Patti GJ, Gunter MJ, Govindan R, Lansdorp-Vogelaar I, Wang T, Townsend JP, Colditz GA, Belkaid Y, Cao Y. Cell. 2026 Apr 16; 2026 Apr 7. PMID: 41997124.
- Exposure to nitrosatable drugs during pregnancy and childhood cancer: A cohort study in Taiwan.Deng C, Hu YH, Sirirungreung A, Chock EY, Liew Z, Ritz B, Lee PC, Heck JE. Int J Cancer. 2026 Apr 15; 2025 Nov 7. PMID: 41203947.
- Evidence supporting European Medicines Agency drug approvals (2020-2023): A cross-sectional study of trial design and outcomes.Siebert M, Caquelin L, Naudet F, Ross JS, Ramachandran R. Clin Trials. 2026 Apr 7; 2026 Apr 7. PMID: 41944409.
- Motivation to Participate in a Nutrition and Physical Activity Intervention During Chemotherapy for Breast Cancer: A Qualitative Study.Puklin LS, Harrigan M, McGowan C, Ferrucci LM, Cartmel B, Zupa M, Deyling M, Sanft T, Sharifi M, Irwin ML. Psychooncology. 2026 Apr. PMID: 42025931.
- Treatment Patterns Across Lines of Therapy for Advanced Non-Small Cell Lung Cancer in the United States.Lee DH, Li Y, Yang SC, Chiang AC, Soulos PR, Gross CP, Wang SY. Cancer Med. 2026 Apr. PMID: 42007970.
- Meta-Analysis of Median Survival Times With Inverse-Variance Weighting.McGrath S, Yang CH, Kimmelman J, Ozturk O, Steele R, Benedetti A. Stat Med. 2026 Apr. PMID: 41998861.
- GDF15 in the tumor microenvironment: A central mediator of cancer immunometabolism and therapeutic resistance.Lu L, Johnson CH, Khan SA, Irwin ML. Cytokine Growth Factor Rev. 2026 Apr; 2026 Jan 13. PMID: 41546893.
- Trends in Smoldering Myeloma Incidence in the United States From Cancer Registries, 2012-2022.Wang R, Davidoff AJ, Schoen M, Huber JH, Feuer EJ, Ruhl J, Neparidze N, Ma X, Chang SH, Wang SY. Am J Hematol. 2026 Apr; 2026 Jan 13. PMID: 41528052.
- Machine Learning Risk Stratification for Older Breast Cancer Survivors: Clinical Care Implications.Wheeler SB, Rotter J, Spees LP, Biddell CB, Trogdon JG, Alfano CM, Mayer DK, Dinan MA, Nekhlyudov L, Birken SA. Health Serv Res. 2026 Apr; 2025 Jul 16. PMID: 40671264.
- School-based exposures to oil and gas development for public school children in the United States.Clark CJ, Campbell E, Grady ST, Buonocore J, Aker A, Deziel NC, Casey JA, Willis M. J Expo Sci Environ Epidemiol. 2026 Mar 28; 2026 Mar 28. PMID: 41904266.
- Blood-based proteomic profiling reveals context-dependent changes in BCL2-associated signaling during taxane therapy in breast cancer patients.Munshani S, Ibrahim EY, Rodwin RL, Ferrucci LM, Blenman K, Lustberg M, Ehrlich BE. FEBS Open Bio. 2026 Mar 26; 2026 Mar 26. PMID: 41883148.
- Update of the Methyltransferase Gene Family: Classification, Evolution and Biological Functions.Katsafadou AI, Falnes PØ, Bruford E, Braschi B, Hanson QM, Hall MD, Thompson DC, Nebert DW, Vasiliou V. Hum Genomics. 2026 Mar 25; 2026 Mar 25. PMID: 41882796.
- Global epidemiology of ovarian cancer: patterns, trends, and risk factors.Li R, Zhao A, Liu M, Lu L, Li B, Zeng H. Cancer Biol Med. 2026 Mar 24; 2026 Mar 24. PMID: 41877375.
- Glutathione is critical for NK cell-mediated immunity.Guerra L, Grusdat M, Kobayashi T, Longworth J, Kurniawan H, Franchina DG, Theodorakis G, Binsfeld C, Verschueren C, Bonetti L, Ewen A, Soriano-Baguet L, Alhamouieh S, Farinelle S, Dostert C, Chen Y, Vasiliou V, Vivier E, Lang PA, Brenner D. Cell Rep. 2026 Mar 24; 2026 Feb 23. PMID: 41734064.
- Cost-Effectiveness of Perioperative Durvalumab With Neoadjuvant Gemcitabine/Cisplatin in Muscle-Invasive Bladder Cancer Treatment.Su ZT, Florissi IS, Geller AE, Johnson Iii BA, Hoffman-Censits JH, Patel SH, Townsend JP, Hahn NM, Kates MR. J Natl Compr Canc Netw. 2026 Mar 19; 2026 Mar 19. PMID: 41911914.
- Impact of Clonal Hematopoiesis of Indeterminate Potential on Treatment Response and Tumor Microenvironment in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy.Yang M, Yin G, Yu Y, Zhang D, Wang X, Zhou X, Liu X, Huang S, Shan Y, Liu X, Wang F, Wang J, Song Y, Wu Y, Liu DX, Yu Z, Xiang Y. J Mammary Gland Biol Neoplasia. 2026 Mar 5; 2026 Mar 5. PMID: 41781761.
- Germline Predisposition to Oncogenic Alkylating Damage in Colorectal Cancer.Gurjao C, Cazaubiel J, Tan C, Reardon B, Hofree M, Ugai T, Meyerhardt JA, Nowak JA, Giovannucci E, Townsend JP, Ogino S, Giannakis M. Cancer Epidemiol Biomarkers Prev. 2026 Mar 2. PMID: 41416871.
- Association of Family History and Polygenic Risk Scores With Prostate Cancer in Africa.Odole I, Andrews C, Agalliu I, Rohan T, Fernandez PW, Irusen H, Ntlaba SJ, Janivara R, Lachance J, Baichoo S, Mensah JE, Adjei AA, Abrahams AOD, Quarchie MN, Aisuodionoe-Shadrach OI, Nwegbu MM, Jamda MA, Oluwole PO, Chen WC, Joffe M, Adusei B, Doherty S, Pentz A, Adebiyi A, Ogunbiyi O, Jalloh M, Rebbeck TR. JCO Glob Oncol. 2026 Mar; 2026 Mar 11. PMID: 41812093.
- Competing subclones and fitness diversity shape tumor evolution across cancer types.Chen H, Shu J, Mudappathi R, Li E, Wang P, Bergsagel L, Yang P, Sun Z, Zhao L, Shi C, Townsend JP, Maley C, Liu L. Bioinformatics. 2026 Feb 28. PMID: 41826799.
- A Taxonomy for Assessing Real-World Targeted Cancer Therapy Options in the Context of Broad Genomic Profiling.Wang X, Long JB, Rothen J, Huang S, Soulos PR, Goldberg SB, Robinson TJ, Ma S, Mamtani R, Presley CJ, Wang SY, Kunst N, Gross CP, Dinan MA. J Natl Compr Canc Netw. 2026 Feb 9; 2026 Feb 9. PMID: 41698347.
- Long-term Mortality Trends Among Individuals With Tuberculosis: A Retrospective Cohort Study of Individuals Diagnosed With Tuberculosis in Brazil.Kim S, Pelissari DM, Harada LO, Sanchez M, Oliveira PB, Johansen FDC, Maciel ELN, Cohen T, Castro MC, Menzies NA. Clin Infect Dis. 2026 Feb 9. PMID: 40249758.
- Overestimation of multiple myeloma survival from cancer registry data.Huber JH, Wang M, Wang R, Schoen MW, Colditz GA, Wang SY, Chang SH. J Natl Cancer Inst. 2026 Feb 6; 2026 Feb 6. PMID: 41652897.
- Adoption and Regional Variation of Prostate-Specific Membrane Antigen Positron Emission Tomography in the United States.Leapman MS, Long JB, Westvold S, Rabil M, Sprenkle PC, Kim IY, Spilberg G, Saperstein L, Fallah J, Suzman D, Lerro CC, Xu J, Rivera DR, Kluetz PG, Karnes RJ, Dinan M, Mitchell AP, Kunst N, Wang SY, Ma X, Gross CP. JCO Oncol Pract. 2026 Feb 3; 2026 Feb 3. PMID: 41632928.
- Exposure to Per- and Polyfluoroalkyl Substances and Liver Cancer: A Systematic Review of Animal and Epidemiological Studies.Tanghal RB, Beglarian E, Stem A, Aung M, Alderete TL, Ducatman A, Vasiliou V, McConnell R, Conti D, Chatzi L. Environ Sci Technol. 2026 Feb 3; 2026 Jan 16. PMID: 41543329.
- Negative Emotions and Breast Cancer Risk for Women with Benign Breast Disease: A Prospective Multicenter Cohort Study in China.Li X, Shan Y, Yu Y, Zhang D, Zhang X, Liu L, Liu DX, Yu S, Guo M, Wang F, Yu Z. Cancer Epidemiol Biomarkers Prev. 2026 Feb 3. PMID: 41378981.
- Exposure to Acetaminophen (Paracetamol) during Pregnancy and Childhood Cancer: A Population-Based Cohort Study in Taiwan.Sirirungreung A, Lee PC, Hu YH, Liew Z, Federman N, Ritz B, Heck JE. Cancer Epidemiol Biomarkers Prev. 2026 Feb 3. PMID: 41342591.
- The association between long-term opioid therapy and composite infection-related dental outcomes.Black AC, Gordon KS, Dziura JD, Barry DT, Crystal S, Edelman EJ, Gibson G, Hamilton M, Jurasic M, Li Y, Marshall BDL, Skanderson M, Suda K, Becker WC. PLoS One. 2026; 2026 Feb 2. PMID: 41628103.
- Dietary vitamin E intake, life expectancy, and mortality risk among adults in the United Kingdom and the United States.Wang S, Bai C, Li G, Cui J, Mao R, Tian J, Lv D, Zhang T, Liu Y, Feng Z, Zhu H. Int J Surg. 2026 Feb 1; 2025 Nov 17. PMID: 41706672.
- Integrating Omics and Pathological Imaging Data for Cancer Prognosis via a Deep Neural Network-Based Cox Model.Li J, Ma S. Stat Med. 2026 Feb. PMID: 41641685.
- Trends in Mortality Associated With Ischemic Heart Disease and Screenable Cancers in the United States, 1999 to 2024.Rana JS, Mszar R, Gianos E, Budoff MJ, Nasir K, Ahmed M. JACC Adv. 2026 Feb; 2026 Jan 19. PMID: 41558364.
- ASO Visual Abstract: Financial Outlook thRough CAncer STorytelling (FOReCAST): Development of a Novel Video-Based Storytelling Intervention to Mitigate Financial Hardship Among Young Women with Breast Cancer.Hamid SA, Moses J, Lynch OF, Washington R, Dicks M, Greenup RA, Proussaloglou EM. Ann Surg Oncol. 2026 Feb. PMID: 41145938.
- Long-Term Outcomes and Cost-Effectiveness of Artificial Intelligence for Breast Cancer Screening: A Modeling Study.Andersen M, Kunst N, Richman IB. Value Health. 2026 Feb; 2025 Sep 20. PMID: 40983310.
- A doubly robust framework for addressing outcome-dependent selection bias in multi-cohort EHR studies.Kundu R, Shi X, Kleinsasser M, Fritsche LG, Salvatore M, Mukherjee B. Biostatistics. 2026 Jan 20. PMID: 41921565.
- Mutational landscape of normal breast tissues adjacent to invasive breast cancer.Suwalska A, Rozenblit M, Harigopal M, Dai J, Liu M, Townsend JP, Marczyk M, Pusztai L. Cell Rep Med. 2026 Jan 20; 2026 Jan 8. PMID: 41512875.
- The impact of Indigenous American-like ancestry on the risk of acute lymphoblastic leukemia in Hispanic/Latino children.Langie J, Chan TF, Yang W, Kang AY, Morimoto L, Stram DO, Mancuso N, Ma X, Metayer C, Lupo PJ, Rabin KR, Scheurer ME, Wiemels JL, Yang JJ, de Smith AJ, Chiang CWK. HGG Adv. 2026 Jan 15; 2025 Oct 25. PMID: 41261530.
- Residential proximity to active and abandoned oil and gas development and risk of childhood Ewing sarcoma in California.Clark CJ, Johnson N, Wang R, Stewart EC, Spector LG, Wiemels JL, Metayer C, Deziel NC, Ma X. Environ Health. 2026 Jan 14; 2026 Jan 14. PMID: 41535920.
- Metabolomic biomarkers of rest-activity rhythms in older women: results from the Women's Health Initiative study.Zhang L, Yeung CHC, Lee KAV, Shadyab AH, LaCroix A, Stone KL, Yaffe K, Hayden KM, Casanova R, Rapp SR, Chen JC, Baker L, Manson JE, Huang Y, Xiao Q. Sleep. 2026 Jan 13. PMID: 41071097.
- Effect of a lifestyle intervention during chemotherapy for breast cancer on quality of life.Puklin LS, Li FY, Ferrucci LM, Cartmel B, Harrigan M, McGowan C, Zupa M, Ligibel JA, Sanft T, Irwin ML. JNCI Cancer Spectr. 2026 Jan 9. PMID: 41452765.
- Body mass index and chemotherapy completion among patients with newly diagnosed ovarian cancer.Cao A, Cartmel B, Ratner E, Li FY, Schlumbrecht MP, Kumar A, Crane TE, Esserman DA, Irwin ML, Ferrucci LM. JNCI Cancer Spectr. 2026 Jan 9. PMID: 41442446.
- DNN-based semiparametric AFT model for integrating genomic and pathological imaging data in cancer prognosis.Li J, Zhang Q, Ma S. Biometrics. 2026 Jan 6. PMID: 41837305.
- Research Priorities and Future Directions in Cardio-Oncology.Mszar R, Ali A, Hull SC, Ferrucci LM, Baldassarre LA, Khera R, Irwin ML, Clasen SC. Curr Treat Options Oncol. 2026 Jan 4; 2026 Jan 4. PMID: 41484494.
- Financial Hardship and Unhealthy Lifestyles: Perspectives and Solutions From Breast Cancer Survivors and Their Care Teams.Pichardo MS, Nsubayi CK, Ginader AS, Peña K, Nguyen TH, Irwin ML, Sanft T, Molina Y, Fayanju OM. Cancer Control. 2026 Jan-Dec; 2026 Mar 11. PMID: 41814123.
- Clinical Trial Patient Matching: A Real-Time, Common Data Model and Artificial Intelligence-Driven System for Semiautomated Patient Prescreening in Cancer Clinical Trials.Gong G, Liu J, Pandya S, Taborda C, Wiesendanger N, Price N, Byron W, Coppi A, Young P, Wiess C, Dunning H, Barganier C, Brodeur R, Fischbach N, LoRusso P, Pusztai L, Kim SY, Rozenblit M, Cecchini M, Mongiu A, Mendez L, Kaftan E, Torre C Jr, Krumholz H, Krop I, Schulz W, Lustberg M, Kunz PL. JCO Clin Cancer Inform. 2026 Jan; 2026 Jan 9. PMID: 41512229.
- Molecular Signature of Cisplatin Resistance in Ovarian Cancer Identifies Therapeutic Opportunities for Re-sensitization.Mansour M, van Ginkel S, Alata M, Bani I, Elhussin I. J Cancer. 2026; 2026 Jan 1. PMID: 41438580.
- Adaptation and Validation of the Fear of Blistering Disease Recurrence Inventory.White MA, Simard S, Yale M, Tomayko MM. Dermatology. 2026; 2025 Dec 9. PMID: 41363691.
- Personalized risk assessment of frailty in long-term cancer survivors.Forman R, Westvold SJ, Long JB, Fan J, Hyslop T, Conlin K, Jacobson S, Wang SY, Leapman MS, Cecchini M, Leeds I, Spees L, Presley C, Yasin F, Taylor M, Kwaramba T, Gross CP, Oeffinger K, Dinan MA. J Geriatr Oncol. 2026 Jan; 2025 Nov 29. PMID: 41319472.
- Patient Experiences in Accessing Reproductive Health Services for Women With Cognitive, Intellectual, and Developmental Disabilities: A Systematic Review.Chang C, Carandang RR, Silverberg J, Surkis C, Cunningham SD, Wang K, Qasba N. Womens Health Issues. 2026 Jan-Feb; 2025 Nov 22. PMID: 41274839.
- Feasibility, safety and outcomes of patients with newly diagnosed acute myeloid leukemia discharged 'early' after intensive induction.Hunter CJ, Cheng W, Bewersdorf JP, Boddu P, Browning S, Halene S, Parker T, Huntington SF, Kothari S, Mendez L, Neparidze N, Sethi T, Barbarotta L, Podoltsev NA, Zeidan AM, Shallis RM. Leuk Lymphoma. 2026 Jan; 2025 Oct 29. PMID: 41160735.
- Cardiovascular risk in long-term survivors of breast, prostate, colon, and rectal cancer.Westvold SJ, Long JB, Fan J, Kc M, Hyslop T, Conlin K, Jacobson S, Silber A, Wang SY, Leapman MS, Leeds I, Spees L, Wheeler SB, Gross CP, Oeffinger K, Dinan MA. J Natl Cancer Inst. 2026 Jan 1. PMID: 41069232.
- Financial Outlook thRough CAncer STorytelling (FOReCAST): Development of a Novel Video-Based Storytelling Intervention to Mitigate Financial Hardship Among Young Women with Breast Cancer.Hamid SA, Moses J, Lynch OF, Washington R, Dicks M, Greenup RA, Proussaloglou EM. Ann Surg Oncol. 2026 Jan; 2025 Sep 24. PMID: 40993463.
- Comparative Risk of Adverse Pancreatic Events With GLP-1 Receptor Agonists, SGLT2 Inhibitors, DPP4 Inhibitors, and Sulfonylureas Among Adults With Type 2 Diabetes at Moderate Cardiovascular Disease Risk.Kalathiya UN, Herrin J, Swarna KS, Deng Y, Polley EC, Neumiller JJ, Galindo RJ, Umpierrez GE, Ross JS, Mickelson MM, McCoy RG. Endocr Pract. 2026 Jan; 2025 Sep 11. PMID: 40945659.
- Incorporating prior information in gene expression network-based cancer heterogeneity analysis.Li R, Xu S, Li Y, Tang Z, Feng D, Cai J, Ma S. Biostatistics. 2025 Dec 31. PMID: 39074174.
- Perspectives of Patients and Providers on Chronic Pain Assessment in Neurofibromatosis Type 1 (NF1): A Qualitative Study.Grau L, Zempsky WA, Martin S, Larkin K, Buono FD. Cureus. 2025 Dec; 2025 Dec 27. PMID: 41602242.
- Why Americans are Dying Younger? NIH Is Not the Problem. Our Broken Healthcare Delivery Is.Ignacio RB, Pagkas-Bather J, Gonsalves G, Gianella S. J Infect Dis. 2025 Dec 20; 2025 Dec 20. PMID: 41420662.
- Why Americans are Dying Younger? NIH Is Not the Problem. Our Broken Healthcare Delivery Is.Ignacio RB, Pagkas-Bather J, Gonsalves G, Gianella S. Clin Infect Dis. 2025 Dec 20; 2025 Dec 20. PMID: 41420651.
- Costs and benefits of early access to new cancer drugs through the US Food and Drug Administration's accelerated approval pathway: retrospective observational study and economic evaluation.Naci H, Shahzad M, Murphy P, Zhang Y, Costa R, Ross JS, Wagner AK. BMJ Med. 2025; 2025 Dec 16. PMID: 41431468.
- HOXA13 overexpression is associated with poor prognosis in colorectal liver metastases(☆).Su DG, Kurbatov V, Wang X, Zeng Z, Paty PB, Johnson CH, Lu J, Khan SA. Surg Oncol Insight. 2025 Dec; 2025 Sep 29. PMID: 41409782.
- Trends in Colon Cancer Colectomy Volume and Inpatient Costs, 2018-2023: A Medicare Analysis.Newton LE, Korves C, Zwain G, Fowler XP, Bellamkonda K, Rosa S, Denny J, Huynh J, Weinberger DM, Justice A, Vashi A, Goodney PP, Wilson MZ, Davies L. J Surg Res. 2025 Dec; 2025 Dec 2. PMID: 41337807.
- Association between prostate radiotherapy and survival among patients with metastatic prostate cancer by extent of disease burden.Palencia PS, Smani S, Zhao X, Kandala K, Sivanesan N, Cavallo JA, Roessler N, Aneja S, An Y, Miszczyk M, Leapman MS. Radiother Oncol. 2025 Dec; 2025 Sep 21. PMID: 40987387.
- Distinct metabolic and genetic alterations in tumors from early-onset versus late-onset colorectal cancer.Janak A, Jain A, Garcia-Milian R, Aladelokun O, Ma X, Paty PB, Khan SA, Johnson CH. Free Radic Biol Med. 2025 Dec 1; 2025 Aug 25. PMID: 40865779.
- Tracing the evolution of single-cell 3D genomes in Kras-driven cancers.Liu M, Jin S, Agabiti SS, Jensen TB, Yang T, Radda JSD, Ruiz CF, Baldissera G, Rajaei M, Li FY, Townsend JP, Muzumdar MD, Wang S. Nat Genet. 2025 Dec; 2025 Aug 18. PMID: 40825871.
- Addressing conceptual and design gaps in the oncology nutrition evidence base during chemotherapy: contributions of the Exercise and Nutrition Interventions to Improve Cancer Treatment-Related Outcomes Consortium.Compton SLE, Wopat H, Lopez-Pentecost M, Agurs-Collins T, Brown JC, Caan B, Demark-Wahnefried W, Elena JW, Ferrucci LM, McGowan C, Puklin LS, Schmitz KH, Thomson CA, Robien K, Crane TE. J Natl Cancer Inst. 2025 Dec 1. PMID: 40680173.
- Barriers and facilitators to a combined strategy of HPV vaccination and cervical cancer screening among Mexican women.León-Maldonado L, Cabral A, Pages G, Brown B, Allen-Leigh B, Lazcano-Ponce E, Xavier Bosch F, Spiegelman D, Torres-Ibarra L, Hernández-Ramírez RU, Egger E, Rivera-Paredez B, Salmerón J. Hum Vaccin Immunother. 2025 Dec; 2025 Apr 2. PMID: 40172917.
- Semaglutide and Tirzepatide Prescribing for Obesity in Patients With Preexisting Comorbid Cancers.Kim C, Dinan MA, Robinson TJ, Ross JS, Jastreboff AM, Krumholz HM, Lu Y. JAMA Oncol. 2025 Nov 6; 2025 Nov 6. PMID: 41196576.
- Risk of Late-Onset Depression in Long-Term Survivors of Breast, Prostate, and Colorectal Cancer.Taylor M, Westvold SJ, Long JB, Hyslop T, Silber A, Forman R, Yasin F, Kwaramba T, Wang SY, Leapman MS, Cecchini M, Leeds I, Spees L, Wheeler SB, Gross CP, Oeffinger K, Dinan MA. JAMA Netw Open. 2025 Nov 3; 2025 Nov 3. PMID: 41296485.
- Interprovider Variation in Initiation of Bone-Modifying Agents for Patients With Prostate Cancer.Mitchell AP, Salner A, Palyca P, Farooki A, Persaud S, Chakraborty N, Bhamidipati D, Klimchuk M, Dinan MA, Leapman MS, Lipitz-Snyderman A, Hamid A, Ostroff JS, Morris MJ. JCO Oncol Pract. 2025 Nov 3; 2025 Nov 3. PMID: 41183247.
- Molecular Reactivity in Maternal Pregnancy Blood and Neonatal Dried Blood Spots Is Associated with the Risk of Pediatric Acute Lymphoblastic Leukemia.Petrick LM, Imani P, Yu M, Dolios G, Dudoit S, Morimoto LM, Ma X, Wiemels JL, Metayer C. Cancer Epidemiol Biomarkers Prev. 2025 Nov 3. PMID: 40932331.
- KRAS G12C-associated immunotherapy benefit in NSCLC is substantially mediated by tobacco-induced tumor mutation burden, not allele-specific effects.Liu M, Townsend JP. Lung Cancer. 2025 Nov; 2025 Sep 16. PMID: 41027389.
- Clinical effectiveness of HPV vaccine by age at vaccination: a matched case-control study.Oliveira CR, Shapiro ED, Sheth SS, Ellingson MK, Johnson NP, Sullivan EL, Querec TD, Unger ER, Niccolai LM. Lancet Reg Health Am. 2025 Nov; 2025 Sep 16. PMID: 41019517.
- Effect of prescribing and deprescribing oxycodone on pain and function in a mouse model of osteoarthritis: impact of polypharmacy and sex on response.Mach J, Blaker CL, Winters B, Otsu Y, Clarke EC, Allore H, Wyk BV, Winardi K, Peel R, Gregson CW, Assareh N, Kourieh M, Hilmer SN. bioRxiv. 2025 Oct 23; 2025 Oct 23. PMID: 41279379.
Centers and other resources
- Yale Cancer Center (YCC)The Center provides the best approaches for the prevention, detection, diagnosis, and treatment of cancer.
- Yale Center for Analytical Sciences (YCAS)YCAS collaborative team provides expertise in the design, conduct, and analysis of health and health care studies, methodological development, and education and training.
- Yale-Griffin Prevention Research Center (PRC)The PRC works with community partners to develop and implement community-based approaches to prevent and control chronic diseases such as heart disease, diabetes, and cancer.