When Isabel Rancu learned she had won the Marshall Scholarship, Dr. Ted Cohen, DPH, MD, MPH, was one of her first calls. A Yale senior studying molecular biophysics and biochemistry with a data science certificate, Rancu joined Cohen’s lab as a first-year student.
Because the Cohen Lab’s infectious disease research requires a strong computational and computer science background, it’s rare for undergraduate students to join. In fact, Rancu is the first undergraduate student to ever work in the lab, said Cohen, professor of epidemiology (microbial diseases). He described how Rancu would spend several hours each week in the lab learning skills that were not taught in her undergraduate classes. “She’s incredibly personable, easy to work with, and smart, asks a ton of questions, and is willing to go away and try things and come back,” Cohen said.
Despite being the only undergraduate in a lab populated with doctoral, post-doctoral, and master’s students, Rancu said she felt incredibly supported. Lab members offered strong mentorship, involving her in lab meetings, and helping her develop research skills. “The group culture has been so good to a young undergrad scientist because it just totally was all about: how can we help each other; how can we support each other?” Rancu said.
During her four years in the lab, Rancu worked on many projects from modeling tuberculosis (TB) transmission to investigating how the TB genome can be sequenced directly from sputum samples. She led a project focused on using genomic data from TB to understand transmission patterns of the disease within communities in Moldova in Eastern Europe. The paper was recently published in a peer-reviewed journal. Rancu’s senior thesis research focused on the bacterial genomics and the bioinformatics behind TB.
As a Marshall Scholar, Rancu will pursue a Master of Research in bioinformatics and theoretical systems biology at Imperial College and a Master of Science in applied infectious disease epidemiology at University College London. Though she isn’t sure of her exact career path, Rancu knows she wants to work at the intersection of public health-oriented infectious disease research, teaching, and clinical care.
“It’s going to be a huge loss for us when she graduates, but we’re so proud of her,” Cohen said.
Rancu said she hopes that more undergraduates will get involved in research at YSPH. “It has been one of the most rewarding experiences of my time at Yale to be part of the lab,” Rancu said.
And to principal investigators like Cohen who are considering taking on an undergraduate student, Rancu joked, “Maybe they’ll just end up as Marshall Scholars!”