Mental Health & Behavioral Research, Phase I

Psychedelics Research Study with DMT in Adults Aged 21 to 65 with Major Depression.

Volunteers
Health Professionals

What is the purpose of this trial?

Adults aged 21 to 65 with major depressive disorder not improved with prescribed anti-depressants, needed for a research study investigating the effects of DMT (psychoactive compound in ayahuasca) in the treatment of depression.

Study compensation up to $750

Find out more about who can participate in this trial

Contact Information

For more information about this study, including how to volunteer, contact Prakash Gupta, MD. Phone ext. 14495

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call 877.978.8343 for more information.

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Principal Investigator

Deepak Cyril Dsouza, MBBS, MD
Vikram Sodhi ’92 Professor of Psychiatry; Director Schizophrenia Neuropharmacology Research Group at Yale (SNRGY); Director, Neurobiological Studies Unit, VACHS; Director, VA-CMHC Schizophrenia Research Clinic; Director, Yale Center for the Science of Cannabis and Cannabinoids ; Chair, Research and Development Committee, VA Connecticut Healthcare System

Sub-Investigators

Last Updated
05/03/2026
Study IRB
#2000034770