From the Lab to the Limelight - Blog version of our #TraineeTuesday Twitter series
Welcome Sahana Kribakaran, PhD, this week’s #TraineeTuesday star! In October, this MD/PhD student published a first-author paper and successfully defended her thesis. Let’s dive into her work on childhood trauma and its impact on mental health.
Advised by Dylan Gee, PhD, in the Clinical Affective Neuroscience & Development lab, Sahana examined the link between trauma exposure and the neural mechanisms of safety signal learning (SSL) — a process used to reduce fear in adults. She found neural circuitry involved in SSL was sensitive to trauma exposure.
“Understanding safety signal learning can not only tell us more about the ways in which we learn about threat and safety in our environment, but also has important implications for mental health conditions that often develop following traumatic experiences, such as posttraumatic stress disorder (PTSD) and anxiety,” Sahana said.
In high school, Sahana read a Scientific American article titled “Faulty Circuits” on the biology of mental disorders. This sparked her fascination with neuroscience, leading her to major in neuroscience at the University of California, Los Angeles, and conduct circuit neuroscience research. Sahana was interested in the impact of environment and experiences on mental health, and was drawn to Yale’s diversity of research.
The goal of her work is to improve therapeutic approaches to anxiety and PTSD. Throughout graduate and medical school, Sahana thought critically about how trauma is beyond the individual and “most often a product of our society’s systems.” To her, the ways we care for one another must shift.