Luis Miguel Mestre, PhD, MS

Luis Miguel Mestre is a Research Health Sciences Specialist at the VA Medical Center in West Haven, CT, and an Associate Research Scientist in the Department of Psychiatry at Yale School of Medicine. His research integrates big data, quantitative epidemiology, and informatics to address chronic diseases and improve healthcare delivery, leveraging real-world evidence from electronic health records. Dr. Mestre’s recent work emphasizes four main areas: substance use prevention—including tobacco and cigarette smoking—health disparities, tobacco cessation, and cancer prevention.

Specifically, his projects focus on identifying high-risk groups for substance use and developing digital interventions for cessation within these domains. Building on this interdisciplinary expertise, Dr. Mestre is a Yale alumnus and former NIDA T32 Postdoctoral Fellow at The Consultation Center, TCORS, and The HABIT Lab. He earned his Ph.D. in Epidemiology with a minor in Data Science from the Indiana University School of Public Health-Bloomington. He also holds an MS in Mathematical Statistics from the University of Puerto Rico, Mayagüez Campus. His doctoral training in quantitative epidemiology, statistics, and data science laid the foundation for his current research in health disparities, chronic diseases, and substance use.