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Yale Legacy Collaborative
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INFORMATION FOR

Welcome Legacy Participants

Thank you for being part of something extraordinary!

Years ago, you joined one of our Adolescent Metabolic Health studies. You are part of a unique group of individuals who helped advance our understanding of how the body processes food into energy. Your contribution has made a lasting difference for communities, health care providers, and scientists.

Connect with us!

Enrolling Now for the Legacy Registry & Biorepository

Legacy Registry

  • You are automatically part of the Legacy Registry, which securely contains results from your original adolescent studies.
  • You do not need to take any action unless you wish to opt out.
  • Privacy is a top priority—your information is protected and never shared without your permission.
  • If you prefer not to be included, simply respond to the opt-out invitation via MyChart, mail, or email. You can also contact us by email.

Official Details of Legacy Registry and Community Engagement Program

Printable Information Document

Legacy Biorepository

Please join the Legacy Biorepository, a storage library for data from your past studies and any new studies you want to join within the Biorepository. Written consent is required to participate. Participation is completely voluntary. You may receive an invitation through:

  • MyChart
  • Email
  • A letter to your last known mailing address

As a participant, you will:

  • Receive invitations to special health studies over the coming years
  • Access your personal study results
  • Have opportunities to collaborate with us on designing future research projects based on participant needs

Please note:

Only individuals who participated in the Adolescent Metabolic Health studies at Yale School of Medicine are eligible for the Legacy Collaborative. If you’re unsure whether you were part of these original studies, feel free to reach out to us—we’re happy to check.

If you are a young person, or parent of a child or teen interested in joining our current Adolescent Metabolic Health studies, please contact us.

Uterine Health and Endometrial Cancer Study

More women are being diagnosed with endometrial cancer, or cancer of the lining of the uterus, especially women under 50 and women of Hispanic descent. Risk factors include:

  • Higher body weight
  • Irregular periods
  • Early onset menstruation (before age 12)
  • Infertility
  • Never having been pregnant

Despite the risks, many women are not offered screening. When endometrial cancer or precancer is caught early, more treatment options are available, and hysterectomy may be avoided.

We will be offering free testing for Legacy participants who are enrolled in this substudy. Please contact us via email.