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    Yale research advances presented at American Society of Hematology annual meeting

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    Key points

    • Dr. Diane Krause receives ASH Advancing Inclusive Excellence Award
    • Dr. Patricia LoRusso presents a Trainee Session on Drug Development with a focus on cancer interception, avoid over-treatment, and use new, lower-toxicity therapies earlier in care
    • Three Yale Hematology-Oncology fellows receive the ASH Hematology Inclusion Pathway (HIP) Fellow Awards

    Physicians, scientists, and trainees from Yale Cancer Center and Smilow Cancer Hospital attended the 67th annual meeting of the American Society of Hematology in Orlando, FL, December 6-9, 2025 to present the latest advances in hematological research and clinical care from Yale.

    Over 50 oral presentations, education sessions, and poster presentations were shared by Yale authors at the meeting highlighting new research in lymphoma, leukemia, myeloid malignancies, sickle cell disease, and classical hematology.

    Additional sessions were led on career development topics, trainee and mentorship sessions, and advances in patient care, including a trainee session on "Drug Development" by Patricia LoRusso, DO, a Satellite Symposium entitled "Medical Crossfire®: Experts Debate the Hottest Topics in AML – FLT3, IDH1/2, KMT2Ar, NPM1, Secondary AML, Maintenance, Novel Combinations, and Emerging Therapies" from Amer Zeidan, MBBS, and numerous oral abstracts and poster presentations sharing the latest data on clinical trials, outcomes research, epigenetics, biomarkers, and more.

    ASH Advancing Inclusive Excellence Award Ceremony

    • Dr. Diane Krause

      Dr. Diane Krause was the recipient of the ASH award for Advancing Inclusive Excellence

    Workshops and Trainee Sessions

    • Dr. Scott Huntington

      Dr. Huntington highlights smart use of databases, key principles for high-quality outcomes research & common analytic pitfalls at a trainee session

    Oral Abstracts

    • Dr. Valentina Restrepo

      Dr. Restrepo presents an oral abstract on burnout in SCD physicians

    Media gallery

    • Dr. Karin Finberg

      Dr. Finberg presents an oral abstract sharing how bone-marrow endothelial cells produce FGF23 during anemia

    Poster Sessions

    • Cameron Hunter's Poster

      Dr. Hunter shares early discharge program cost savings for patients with newly diagnosed acute myeloid leukemia after intensive induction chemotherapy

    Media gallery

    • Dr. Hee Doo Yang and Dr. Stephanie Halene

      Dr. Yang describes how blocking METTL3 in leukemia cells triggers DNA-RNA hybrids, DNA damage, and immune activation. Removing R-loops protects the cells, showing they drive the effect—paving the way for new AML therapies

    Media gallery

    • Dr. Scott Huntington's Poster Session

      Dr. Huntington, pictured with Caroline Reyes, Sophia Li, and Dozie Enechebe, shares that in older adults with CLL, venetoclax-based therapy led to longer survival and delayed need for next treatment compared to other regimens

    Media gallery

    • Dr. Nurefsan Sariipek's Poster Session

    Media gallery

    • Dr. Sarah Hinderstein's Poster Session

      Dr. Hinderstein shares research showing SCD monocytes react more strongly to TLR7/8 stimulation, suggesting altered innate immunity that may affect infection and vaccine responses

    Views from the Conference

    • ASH Conference Center

    Media gallery

    • ASH Meeting 2025

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