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Sleep Well, Bee Well – A Focus on Early Childhood Sleep to Promote Parent-Child Relationships and Reduce Health Disparities

June 04, 2024

YCSC Grand Rounds June 4, 2024
Monica Lynn-Roosa Ordway
Associate Professor of Nursing

ID
11755

Transcript

  • 00:00Good afternoon, everyone.
  • 00:02Welcome to Grand Rounds.
  • 00:04Thank you so much for you all adjusting
  • 00:06to this slight change to virtual format.
  • 00:09We really appreciate you
  • 00:11accommodating this change.
  • 00:12It's a brief return to a virtual
  • 00:13format and well worth it.
  • 00:15So that we can hear from Doctor Ordway today.
  • 00:17And we will be back in person next week
  • 00:19for Grand Rounds in the Cohen Auditorium,
  • 00:22where we'll have our Viola Bernard
  • 00:24lecturer from John Pachanka.
  • 00:27He'll talk about LGBTQ
  • 00:29affirmative healthcare.
  • 00:30Please do join us in person
  • 00:32for that if you can.
  • 00:33And to today's speaker,
  • 00:35someone who needs no introduction
  • 00:37for our community And Doctor Monica
  • 00:40Ordway after 10 years working
  • 00:42as a nurse practitioner and Dr.
  • 00:44already returned to the Child
  • 00:46Study Centre to complete her PhD
  • 00:48and her postdoctoral fellowship
  • 00:49working with Lil Sadler, Linda Mays,
  • 00:52Nancy Suckman,
  • 00:52working on Mothering from the inside
  • 00:54out and Minding the Baby program and
  • 00:57since then joined the School of Nursing,
  • 00:59now an associate professor and Co
  • 01:01director of Yale Byway Behavioral
  • 01:03and Translational Research programme.
  • 01:05Really leading an impressive clinical
  • 01:07research programme that seeks to
  • 01:09address parenting and also sleep as a
  • 01:12modifiable risk factor that can help
  • 01:14address health inequities very early in life.
  • 01:17Doctor Ordway has been funded by the
  • 01:19National Institutes of Health and
  • 01:21the National Institute of Nursing
  • 01:22Research as well as various foundations
  • 01:24and has fellow the American Academy
  • 01:26of Nursing as well as a board
  • 01:28member of the International Sleep
  • 01:30Association and sits on the Nanos
  • 01:33Scientific and Medical Advisory Board.
  • 01:36Doctor,
  • 01:36we're so pleased that you can join
  • 01:38us for grand rounds today and I
  • 01:40can't wait to learn from you.
  • 01:41And I'm welcome you back to the
  • 01:43Child Study Centre.
  • 01:45Thank you. That's very generous.
  • 01:46I'm very happy to be here.
  • 01:48Sorry to do it via Zoom today but I was
  • 01:51telling them I am at the APSS big sleep
  • 01:54conference annual sleep conference.
  • 01:56So it's AI was happy to to fill in
  • 01:59but I did have to do it remotely.
  • 02:02So thank you for having me.
  • 02:03Just one small correction is that
  • 02:05I my PhD was at the School of
  • 02:09Nursing but I did but I had a A31
  • 02:12that Linda Mays was a Co sponsor on
  • 02:15with me in addition to Melissabbas.
  • 02:18So I will share my slides and
  • 02:20we'll get started.
  • 02:28Thank you, Tara, for putting
  • 02:30in the CEU information.
  • 02:31We'll get the CME code into
  • 02:32the chat shortly as well.
  • 02:36OK. So hopefully this OK,
  • 02:48All right. So today I'm going to
  • 02:49talk to you about sleep Well be well,
  • 02:51that's not a typo.
  • 02:53That is an intervention that I've
  • 02:56developed for early intervention and
  • 02:58sort of have this this be theme going.
  • 03:01It's I want to focus on early childhood
  • 03:04sleep to promote parent child relationships
  • 03:07and reduce health disparities.
  • 03:10Today we'll talk about understanding
  • 03:11the importance of sleep and
  • 03:13early child development.
  • 03:15Can I want to ask two, can you hear me OK?
  • 03:16I've never used my ear buds
  • 03:18for with my laptop before,
  • 03:20so I just want to make sure, OK.
  • 03:23And then secondly,
  • 03:24to identify barriers to healthy sleep and
  • 03:26historically marginalized populations.
  • 03:28And then to describe the potential of
  • 03:30sleep health promotion interventions
  • 03:32in clinical and community settings in
  • 03:35order to improve sleep outcomes and
  • 03:37strengthen parents child relationships.
  • 03:39So to kind of put this in context,
  • 03:40I know you briefly mentioned that my
  • 03:43pre doctoral work was in with minding
  • 03:46the baby and I participated with
  • 03:48them and my dissertation study was
  • 03:50following up with the families that
  • 03:53participated one to three years earlier.
  • 03:56So the children were three to
  • 03:57five years of age and I and I re
  • 04:00recruited them and followed them.
  • 04:02And it really,
  • 04:04I love my work with minding the baby,
  • 04:07not just because it's a phenomenal team
  • 04:09and you're very lucky to have Krista
  • 04:11there at the Child Study Center now,
  • 04:14but because it really helped me.
  • 04:18So many questions that I have for
  • 04:20my clinical work as a pediatric
  • 04:22nurse practitioner in a primary
  • 04:23care Center for 10 years really came
  • 04:27to be understood when I thought
  • 04:29about reflective functioning and
  • 04:31the parent child relationship and
  • 04:33thinking about the mental state
  • 04:35that underlies children's behavior.
  • 04:37And I sort of wish I had understood
  • 04:40that concept better when I
  • 04:41was working with families.
  • 04:42It would have really helped me understand,
  • 04:45particularly as a lactation consultant,
  • 04:46the family that I was working with early
  • 04:48on who would struggle with parenting.
  • 04:50So I just saw such a great connection
  • 04:53between this concept and and primary care.
  • 04:56So I had written a paper,
  • 04:58one of my papers on how to implement
  • 05:01parental reflective functioning
  • 05:03in a primary care setting.
  • 05:05I then was still at the end of my,
  • 05:09I was struggling with how am I going to
  • 05:12get this concept into pediatric primary
  • 05:14care where we see patients every 15 minutes.
  • 05:17And so it's very difficult to fit in talking
  • 05:20about attachment theory and parenting.
  • 05:23And so I then went on to work as a
  • 05:26postdoc with doctor Nancy Bookman and
  • 05:29who has unfortunately passed away,
  • 05:32but was a phenomenal mentor and
  • 05:36working with me to in a in a
  • 05:40shorter short term mentalization
  • 05:42based intervention program.
  • 05:43So I helped lead the meeting,
  • 05:47engaged sort of translation of her
  • 05:49mothering from the inside out to
  • 05:52the West Haven Mental Health clinic.
  • 05:54But again, once I became onto faculty
  • 05:58in 2013 at the School of Nursing,
  • 06:00what I was struggling with was still,
  • 06:03how do I get this back to primary care?
  • 06:05And at the same time,
  • 06:06just the year prior,
  • 06:09eco bio developmental framework that
  • 06:11I'm sure you're all familiar with
  • 06:13was published this the year before.
  • 06:15And it's one of those things that when
  • 06:16you're going through your doctoral
  • 06:18studies and then something changes
  • 06:20in a new theory or new approach.
  • 06:23And it's sort of, oh,
  • 06:23I wish that was there when I
  • 06:25was doing my dissertation work.
  • 06:27And so this made a lot of sense to me.
  • 06:29But I what I think finally clicked for me
  • 06:35and in my first year or two and faculty
  • 06:37was it something was missing here.
  • 06:39So as we know that we have ecology
  • 06:41mixing with biology influencing
  • 06:43health and development.
  • 06:45But I really thought about these
  • 06:48foundations of healthy development and
  • 06:50how much they the work I was doing my
  • 06:53being post doc was related to this.
  • 06:54But what was seemed to be missing
  • 06:56was sleep as a foundation of health.
  • 06:58And once I sort of came to that
  • 07:01conclusion and realizing, you know,
  • 07:03sleep is a pillar of health and early
  • 07:05childhood and it gets a very little
  • 07:08attention and I think emphasized by
  • 07:10the fact that it was missing as a
  • 07:13foundation of health in this model
  • 07:15as well as I will let you know that
  • 07:18the first definition of pediatric
  • 07:20sleep health was published in 2021.
  • 07:22So that's really I think a statement
  • 07:25about a sort of our under recognition
  • 07:29of sleep health and more of a focus
  • 07:32on sleep disorders.
  • 07:33So most of what's been focused
  • 07:34on in the field of sleep has been
  • 07:35in sleep disorders.
  • 07:36And I think this is a great sleep
  • 07:39is a topic that in your work
  • 07:42when child development work,
  • 07:43parenting work has a has a great place.
  • 07:48Obviously today was a pioneer in
  • 07:51pediatric sleep research and he
  • 07:53published this transactional model of
  • 07:56infant sleep and you can see that the
  • 08:00most proximal relationship here was in
  • 08:03this model is around that the parent.
  • 08:06Let me just see if I can get my
  • 08:08pointer here is this, you know,
  • 08:10parent child interactive context.
  • 08:14And so this again was just a perfect
  • 08:16way of me bridging the work I was
  • 08:19doing in my pre and post doc.
  • 08:21And I have using sleep as a back doorway
  • 08:26of talking to primary care providers
  • 08:29about how to introduce concepts about
  • 08:32parenting into their routine practice.
  • 08:35So I just like a little bit of background on
  • 08:37how I got to the point of studying sleep.
  • 08:39And it's a little unusual,
  • 08:40I think that I have been doing all
  • 08:44this work now and something that
  • 08:46I did not get my PhD in.
  • 08:47And sleep is a topic,
  • 08:48but it's,
  • 08:49it's been a really fun experience and I've
  • 08:52had some great mentors along the way.
  • 08:54So the importance of sleep
  • 08:56and early childhood.
  • 08:56We know that adequate sleep is essential
  • 08:59for cognitive, physical and emotional
  • 09:01development in young children.
  • 09:03It, it, the brain is undergoing
  • 09:05rapid growth and development,
  • 09:06as we know in this early childhood period.
  • 09:09And sleep actually plays a really critical
  • 09:12role in facilitating this process.
  • 09:14And it's interesting to note also
  • 09:16that Sleep Medicine in general is a
  • 09:19fairly young specialty in Pediatrics
  • 09:22or in in health medicine in general.
  • 09:26It's the first sort of Sleep
  • 09:28Medicine as a as a separate,
  • 09:30the focus was in 1972.
  • 09:32So it's, it's something that's
  • 09:35continuing to grow as I can say that I,
  • 09:38I Co chaired the IPSA international
  • 09:40sleep conference last month and
  • 09:42we had four times the number of
  • 09:45submissions in our abstracts and five
  • 09:47times the number of applications to
  • 09:50our pediatric sleep research award.
  • 09:53There's definitely a a growing feel that
  • 09:55I'm glad to see that sufficient sleep
  • 09:58really helps children to consolidate
  • 10:00their memories to improve salts
  • 10:03problem solving skills and enhance
  • 10:05their overall cognitive abilities.
  • 10:07So the benefits include things we I
  • 10:10just mentioned memory, attention.
  • 10:14I often wonder in with all the patients
  • 10:16that saw in primary care with ADHD.
  • 10:19One of my sort of future hopes is
  • 10:23that we include screening for sleep
  • 10:26disorders before we prescribe stimulants.
  • 10:29Oh, is that Nancy close?
  • 10:30Did I see you there? So nice to know Nancy.
  • 10:34I was on my dissertation committee and
  • 10:35it's been a while since I've seen her.
  • 10:37So sorry.
  • 10:37I just got a little distracted
  • 10:39by the by her lovely face.
  • 10:42Sleep also effects the behavior
  • 10:45and we can think about this for
  • 10:47ourselves as well as children,
  • 10:49learning and overall health.
  • 10:51It's all a factor of adequate sleep.
  • 10:56There are four stages of sleep REM
  • 10:59sleep during REM sleep we have
  • 11:01the brain is actually very active.
  • 11:03They're moving back and forth and this
  • 11:05stage is the stage that we're learning
  • 11:08is really essential for memory consolidation,
  • 11:10positive development and emotional
  • 11:13regulation in young children.
  • 11:15And then our non REM sleep those.
  • 11:17There are three stages of non REM
  • 11:19sleep and this is light to deeper
  • 11:21sleep where the brain activity
  • 11:22and eye movements are,
  • 11:24they're less pronounced,
  • 11:25but it's it's still important for growth,
  • 11:28immune function and restoration
  • 11:30of the body's energy,
  • 11:31particularly in stage 3,
  • 11:33which we refer to as slow wave sleep.
  • 11:35That's the portion of sleep where
  • 11:38growth hormone is released and
  • 11:40where it's very restorative.
  • 11:42So I spent,
  • 11:43I in my first grant as at age 23 and,
  • 11:47and back up to,
  • 11:48I was studying sleep,
  • 11:49which I'll talk about a little bit,
  • 11:51but I started,
  • 11:52I was offered an opportunity to
  • 11:53work as a nurse practitioner in our
  • 11:55pediatric sleep clinic here at Yale.
  • 11:57And so I did that for five years.
  • 11:59And when I would look at polythenography,
  • 12:01I'm really interested in,
  • 12:03you would see sometimes patients
  • 12:06that would tell you that they have,
  • 12:08you know, 8/10/12 hours of
  • 12:10sleep depending on their age,
  • 12:12but the percentage of their slow wave
  • 12:14sleep and REM sleep would be very low.
  • 12:17So we typically want to see 25% in each of
  • 12:20those stages and 50% in stage one and two.
  • 12:23And this often maybe helped me to explain
  • 12:26that even though you're sleeping for,
  • 12:29you know, the recommended amount of time,
  • 12:30if you don't feel rested,
  • 12:31it's likely that you're not getting
  • 12:34enough low wave in REM sleep.
  • 12:36So these stages are important for
  • 12:39the overall brain development and
  • 12:41their well-being and a balanced sleep
  • 12:43schedule that includes both R.E.M.
  • 12:44and non R.E.M.
  • 12:46is crucial for children's
  • 12:47overall development.
  • 12:49And where this,
  • 12:50what is important is I think
  • 12:52a question we're going to talk
  • 12:55up today about sleep health
  • 12:57disparities and inequities.
  • 13:01The literature suggests that
  • 13:02sleep health and equities in
  • 13:04early childhood that they're very,
  • 13:06they're highly significant if you're just
  • 13:09looking at night time sleep duration.
  • 13:11But if you include 24 hour sleep,
  • 13:14they include the nap, the inequity
  • 13:17actually becomes less significant.
  • 13:19And so the the thinking is that for
  • 13:24minoritized race and ethnic groups
  • 13:26that children are having longer and
  • 13:30more naps and sleeping less at night.
  • 13:33And so I think the question remains, what is,
  • 13:37what does that mean for health?
  • 13:39Are we, is it the 24 hours sleep
  • 13:41that's most associated with positive
  • 13:43health outcomes or the night time
  • 13:46sleep duration that's most important?
  • 13:48And I personally hypothesize that it's
  • 13:50the night time sleep duration because
  • 13:52of the multiple sleep cycles that we
  • 13:55have to go that we go through at night.
  • 13:57And if we're, if we have a shorter
  • 13:59period of sleep at night time,
  • 14:01I, I wonder if some of the health
  • 14:04inequities we're seeing could be
  • 14:06somewhat explained, you know,
  • 14:08partially explained by having fewer
  • 14:10cycles and therefore less opportunity
  • 14:12to get to slow weight and REM sleep,
  • 14:15which by the way,
  • 14:16don't happen until later in the
  • 14:18night time period.
  • 14:19So I hope that makes sense that,
  • 14:21you know, quicker or shorter,
  • 14:23even a longer nap during the day is
  • 14:25not going to give you multiple cycles
  • 14:27of slow wave sleep and REM sleep.
  • 14:29And in fact,
  • 14:31we diagnosed narcolepsy by looking
  • 14:33whether or not somebody would
  • 14:35get into REM sleep and,
  • 14:38and a short 20 minute nap period.
  • 14:41You should not get to REM in a short nap.
  • 14:47So there are multiple factors
  • 14:49that would affect sleep and early
  • 14:51childhood screen time is one of them.
  • 14:54I there was a recent call for
  • 14:56children and screen foundation for
  • 14:59looking at screen use and infancy.
  • 15:01And when somebody sent me
  • 15:02the call for proposals,
  • 15:04I thought that's ridiculous,
  • 15:06you know, under one years of age.
  • 15:08But actually when I submitted and
  • 15:11that proposal did end up submitting
  • 15:13a proposal and on that 35% of infants
  • 15:17actually have their own moving device.
  • 15:21So it's being used quite often
  • 15:24even in early childhood.
  • 15:26Bedtime routines are extremely important,
  • 15:29but often this not well described
  • 15:34not just in terms of the content
  • 15:37of the bedtime routine,
  • 15:39but also how to structure them and
  • 15:43the importance of routines in general.
  • 15:45But how is that a recommended
  • 15:47sleep bedtime routine would be,
  • 15:48you know,
  • 15:492020 minutes or so with the same thing
  • 15:53being done consistently each night.
  • 15:56Routines we're finding are
  • 15:58incredibly helpful for for young
  • 16:02children sleep environment.
  • 16:03So having a dark,
  • 16:05quiet,
  • 16:05comfortable sleep environment
  • 16:07with comfortable temperatures
  • 16:08and middle distract distractions
  • 16:10can promote better sleep.
  • 16:12I had what was an older,
  • 16:15I had a case in a clinic.
  • 16:18Want to say, let me preface this to say
  • 16:21that when we're working with families and
  • 16:24asking them about the sleep environment,
  • 16:27really being thoughtful about asking
  • 16:29questions about where children sleep.
  • 16:31Families are bringing their children
  • 16:33into the back of the house.
  • 16:35So they're further away from gun violence,
  • 16:38further away from the front,
  • 16:40from the door, quieter.
  • 16:43They are often crowded homes.
  • 16:46I've done home visits where where
  • 16:49the space was for sleeping and,
  • 16:52and the space that the family had in
  • 16:54the in a friend's house was a bed and
  • 16:56a dresser and there wasn't even room
  • 16:57for me to sit to do the home visit.
  • 17:00So I was standing during that time.
  • 17:02And so when we're asking about Co sleeping,
  • 17:04we're really we need to understand,
  • 17:06is it intentional reactional,
  • 17:08or is there something, you know,
  • 17:11socio economically that's going on
  • 17:13that maybe they weren't able to either
  • 17:15afford a a separate space or they
  • 17:18physically don't have a separate space.
  • 17:20Caffeine intake is an interrupter in sleep,
  • 17:26stress and anxiety and also
  • 17:28physical activity.
  • 17:29As we know,
  • 17:30many kids are not getting adequate
  • 17:32physical activity activity.
  • 17:33And so there's quite a connection
  • 17:35there with with sleep.
  • 17:38So we all know that early brain
  • 17:40development that genes are the blueprint,
  • 17:42but that what really kind of
  • 17:45shapes the brain development is
  • 17:47are there are our experiences.
  • 17:49So whether or not a solid brain
  • 17:51will provide a weak or strong
  • 17:53foundation for future learning is
  • 17:56is the experiences are very key.
  • 17:57And I would say sleep and at
  • 17:59bedtime routine is one of those
  • 18:01opportunities for experiences to
  • 18:03help to build a stronger connection.
  • 18:07As William Dement,
  • 18:08who is a sleep expert, has said,
  • 18:11adequate sleep is essential for the
  • 18:14proper development and maturation
  • 18:15of the brain and to facilitate
  • 18:17the consolidation of memories and
  • 18:19processing of information and overall
  • 18:22optimization of cognitive functions.
  • 18:25This is just a timeline associated
  • 18:28with where sleep plays a role here.
  • 18:31So at two to three months there's
  • 18:33the emergence of sleep wake
  • 18:35cycles before two to three months
  • 18:37sleep in children is 50% R.E.M.
  • 18:40and 50% non R.E.M.,
  • 18:41only two stages and they are
  • 18:45not regulated by the by light.
  • 18:48So when we talk about not doing any
  • 18:51sleep training before six months,
  • 18:53this early age group particularly it,
  • 18:57it would be futile to try to change
  • 18:59any of the sleep patterns at this
  • 19:02early age because they're not,
  • 19:04they're not even into the sleep cycles yet.
  • 19:06At around six months,
  • 19:08we start to see an increase in
  • 19:10consolidation of night time sleep,
  • 19:12so more regular nap and the majority of
  • 19:16that period of sleep happening at night,
  • 19:20as well as the development
  • 19:21of the sleep stages.
  • 19:22So the earliest we would even
  • 19:23really talk about sleep training,
  • 19:25if that's something that the family wanted,
  • 19:27would be 6 months.
  • 19:28And then around 12 months,
  • 19:30we see the maturation of the sleep cycles
  • 19:33to be more similar to an adult pattern,
  • 19:37but there's still recommendation
  • 19:40of sleep recommendation.
  • 19:42Duration recommendation is
  • 19:44about half the time sleeping,
  • 19:46half the time awake and
  • 19:47and build this young age,
  • 19:49which I think speaks to their the
  • 19:53need of sleep for their development.
  • 19:55And then at 24 months,
  • 19:57there's a continued refinement
  • 19:58of their sleep architecture
  • 20:00and typically more scheduled.
  • 20:04Nap around 18 months,
  • 20:06they would likely go from 2:00 to to one nap.
  • 20:11This is one of my favorite slides
  • 20:13to highlight the role of sleep.
  • 20:16And so you've probably seen this
  • 20:17type of slide before where there
  • 20:19are these sensitive periods of
  • 20:21brain development and at the
  • 20:22bottom the year years of age.
  • 20:25And what I think is something to
  • 20:27highlight is that this is the
  • 20:29period where sleep consolidation
  • 20:30is happening and whether all of
  • 20:32what I just described is happening.
  • 20:34And so it's it's happening these
  • 20:38very sensitive periods.
  • 20:40So I see sleep as an opportunity
  • 20:43again to intervene.
  • 20:44One of the things that I would
  • 20:48like to add is that sleep is a
  • 20:50potential buffer to toxic stress.
  • 20:52And I think we haven't studied that enough.
  • 20:54I had the privilege of Co authoring a
  • 20:58chapter with Doctor Judy Owens at Harvard,
  • 21:00who's like the pediatric sleep
  • 21:04mother pediatric sleep, I would say.
  • 21:06And it was in the first social textbook
  • 21:08on social epidemiology of sleep.
  • 21:11And in this chapter we just tried to
  • 21:14highlight a lot of the things that of the
  • 21:18so the how's sleep and look and among
  • 21:23children with socioeconomic adversity.
  • 21:26We've already talked about
  • 21:27how important it is.
  • 21:29What we haven't talked about is
  • 21:31how young children often do not
  • 21:33obtain sufficient sleep and this can
  • 21:35really lead to poor health risks.
  • 21:38Specifically,
  • 21:3825 to 40% of children before the
  • 21:42age of four are sleep deficient.
  • 21:45And this continues on across and to
  • 21:48throughout childhood, adolescence.
  • 21:49The goal of Healthy People 20-30
  • 21:52now is to get 1/3 of adolescents
  • 21:56to have adequate sleep.
  • 21:59So more than 2/3 of adolescents
  • 22:01are not getting adequate sleep,
  • 22:03and even more than that by
  • 22:05the time they're four.
  • 22:06There's also been emerging research
  • 22:09suggesting that sleep disparities
  • 22:10occur as early as one year of age.
  • 22:12This is happening very early.
  • 22:15And they as we know that race
  • 22:17and ethnicity as these are all
  • 22:19social constructs should not be,
  • 22:21you know,
  • 22:22biologically explained why we're seeing
  • 22:26these sleep disparities and we need
  • 22:29to have more behavioral sleep interventions.
  • 22:32But BFIS behavioral sleep
  • 22:34interventions and tested with diverse
  • 22:36multi ethnic low income children,
  • 22:39most of the we have found that behavioral
  • 22:41sleep interventions are highly effective,
  • 22:43but they have been predominantly tested
  • 22:46with a white middle class population.
  • 22:52So as I mentioned about sleep as a
  • 22:55potential buffer to toxic stress and I
  • 22:58started to my first study was looking
  • 23:01at the emerging link between allsthetic
  • 23:04load on the body from prolonged stress
  • 23:07response and sleep disturbances.
  • 23:09And I want to look at multiple biomarkers
  • 23:15and some of the Lyrica suggested that
  • 23:17shorter sleep duration was associated
  • 23:18with some of the biomarkers like CRP,
  • 23:20cortisol and BMI.
  • 23:24So in my case, I studied the extent
  • 23:28to which socioeconomic adversity was
  • 23:30associated with sleep characteristics.
  • 23:32And my hypothesis and specific
  • 23:36aims were really to to describe
  • 23:39sleep health and early childhood,
  • 23:4112 to 15 months of age and to
  • 23:44examine the extent to which the sleep
  • 23:47characteristics were associated with
  • 23:48stress biomarkers and identify some buffers,
  • 23:53moderators to adversity and stress.
  • 23:57So the longitudinal cross-sectional
  • 24:00study for home research visits that I
  • 24:02did in their home if they allowed me to
  • 24:05or in a place that was convenient to them,
  • 24:07included paper and pencil questionnaires,
  • 24:10ethnography to give us a objective
  • 24:12measure of sleep. That's something else.
  • 24:14It's been largely missing a lot
  • 24:16of self report of sleep,
  • 24:17but I wanted the objective markers and then
  • 24:21collected salivary and hair biomarkers.
  • 24:24This sample was 113 healthy
  • 24:28toddlers from 12 to 15 months,
  • 24:30English or Spanish speaking.
  • 24:32I recruited them primarily
  • 24:33through the primary care center.
  • 24:35I looked at adversity, sleep,
  • 24:38rest response, and then for outcomes,
  • 24:39looked at behavioral health outcomes,
  • 24:42looking at the using the,
  • 24:45the brief and the other social
  • 24:47and emotional assessments.
  • 24:51I've faced many challenges.
  • 24:52One of the things that I want I
  • 24:55would highlight as if you haven't
  • 24:56had the opportunity to work with
  • 24:59the cultural ambassadors at YCCI.
  • 25:01They're amazing and they really helped me to
  • 25:06both frame the study to the community,
  • 25:10but also helped me to address any
  • 25:12of the challenges that I that I
  • 25:14came up with and I had. This is
  • 25:19it's a separate story but
  • 25:20and not for this talk,
  • 25:22but I was 10 participants into this
  • 25:27when I had a pediatrician in New
  • 25:31Haven right to the chief medical
  • 25:34officer of Yellow Haven and accused
  • 25:36me of scientific misconduct and
  • 25:38insisted my study be stopped because
  • 25:41I was collecting activity using like
  • 25:45a Fitbit type of device which is
  • 25:48put on the ankle of the toddlers.
  • 25:49And he had said that that was akin
  • 25:52to I was traumatizing that toddlers
  • 25:54and so it was a very stressful time
  • 25:57and the cultural ambassadors were
  • 26:00really helpful in navigating that.
  • 26:04Obviously I'm still here.
  • 26:06So I fortunately,
  • 26:07my protocol was was scrutinized
  • 26:10and and found to be appropriate,
  • 26:13but it also, you know,
  • 26:16really does highlight the importance
  • 26:18of working when you're working in
  • 26:20the community to talk with with
  • 26:22those people like the community
  • 26:24ambassadors to help you or navigate
  • 26:26and and address concerns.
  • 26:32This was one of the things people
  • 26:35have heard the whole story about what
  • 26:37happened when I was 10 participants in.
  • 26:39I usually they say I,
  • 26:40I can't believe you stayed in.
  • 26:42I was a new assistant professor
  • 26:43and we had a new Dean that was
  • 26:46only here for about 6 weeks.
  • 26:47And I said, you know,
  • 26:49if it hadn't been for the 1st 10
  • 26:51participants and the positive feedback
  • 26:53I was getting from the families
  • 26:55that wanted me to do this study,
  • 26:57I probably would have quit.
  • 26:59And examples of how committed
  • 27:02these participants were.
  • 27:04I wanted to share with you here that,
  • 27:08you know,
  • 27:08a text message that I got that the family
  • 27:11was concerned because they had put their,
  • 27:13their child put their foot in a,
  • 27:15a mop bucket.
  • 27:16And so they were worried.
  • 27:18I got A at 6:00 PM from a father
  • 27:20who told me that he was sorry he
  • 27:23had he's been at the hospital
  • 27:25all day because his child was at
  • 27:27the daycare center and had pulled
  • 27:30off the fire extinguisher off the
  • 27:33wall and it landed on his toe and
  • 27:36amputated a portion of his toe.
  • 27:39And he wanted to let me know that,
  • 27:41you know,
  • 27:42that they that he went back to
  • 27:45the daycare and retrieved the
  • 27:46lot for me to act a lot.
  • 27:48I was just overwhelmed that he
  • 27:51thought to call me and he clearly was
  • 27:53dealing with a trauma with his child.
  • 27:55But they were just so everyone,
  • 27:57the participants were so wonderful
  • 27:59to work with and it kept validating
  • 28:01this is an area that they want to
  • 28:04investigate and they want help with.
  • 28:08I talked about the study design already.
  • 28:10This is a picture of the actor
  • 28:11graph on the right hand side
  • 28:13that I said was like a Fitbit.
  • 28:15And you'll notice that it had now I covered
  • 28:18it with a colorful duct tape when I,
  • 28:20I had not done that before the
  • 28:23complaint had come in and I 'cause
  • 28:25I had thought I would just keep
  • 28:27it sort of neutral and, and,
  • 28:29you know, not call attention to it.
  • 28:32But then I thought, well,
  • 28:33maybe it's better for me to make it
  • 28:36look more playful and more childlike.
  • 28:38So one of the things I did was to
  • 28:41try and come up with an idea was to
  • 28:44cover in this powerful duct tape.
  • 28:46Another concern that came up was around this,
  • 28:49which is a light meter.
  • 28:51But I had participants asked me
  • 28:53if it was a camera.
  • 28:55So some other community gave little
  • 29:01comments to to that you wouldn't necessarily,
  • 29:04you know, have thought about without
  • 29:06really engaging with the community.
  • 29:09So in our results, we had 44 black,
  • 29:1228% Hispanic, 22% non Hispanic
  • 29:16white on the mean age of the IT was
  • 29:19primarily mothers 29 1/2 years old.
  • 29:21More than half of them
  • 29:23were unemployed and single.
  • 29:25All of the families were at an income
  • 29:28to need average income to needs of .9.
  • 29:32So they were predominantly
  • 29:33living in poverty, below poverty,
  • 29:36most of them with a high school or less
  • 29:39in high school education and we had
  • 29:45most of that 77% was rent
  • 29:48view owned their homes.
  • 29:50The children were on average 13.8
  • 29:53months of age and 25% of them had been
  • 29:58involved in Child Protective Services.
  • 30:00At some point there we saw that children
  • 30:04were not getting enough night time sleep.
  • 30:06We would like to see at this age that
  • 30:11children were getting closer to 10-11
  • 30:13hours of night time sleep and then
  • 30:16about two hours of daytime sleep.
  • 30:18So they were shy of that.
  • 30:21We the MSFC is the means where
  • 30:25mean successful square differences
  • 30:27of total 24 hours sleep.
  • 30:29So the night to night sleep
  • 30:32variability was over three hours.
  • 30:34Their average bedtime,
  • 30:35which we would recommend to be
  • 30:37about 8:00 PM for this age group was
  • 30:42close to 10:00 and their variability
  • 30:45at bedtime was over 2 1/2 hours
  • 30:48from one night to the next.
  • 30:50This is an example of the output
  • 30:53of sleep activity that you can get.
  • 30:55And just to Orient you,
  • 30:57the light blue is a sleep period.
  • 31:00The yellow wiggly lines are
  • 31:03light from the light meter.
  • 31:05The black lines are activity.
  • 31:09These blue bars at the top I manually
  • 31:12code to indicate daytime nap.
  • 31:15This is midnight,
  • 31:17so you can see this child on this 12
  • 31:21month old had a very late bedtime.
  • 31:26This would be 9:00 bedtime.
  • 31:28So they're quite far from that.
  • 31:31This would the average and the
  • 31:35and the yellow is showing a
  • 31:38variability in their night time bed,
  • 31:41their bedtime.
  • 31:44I did not intend to look at race
  • 31:46and ethnicity differences in my came
  • 31:48because I was looking at 12 months old.
  • 31:50So I, I again, this was before birth
  • 31:54report of the early berries was public.
  • 31:58And so when we did look at racing as to
  • 32:01see what we found was that white children
  • 32:04were typically going to bed before 9:00.
  • 32:07Black children, fathers were going to
  • 32:11bed at 10:16 PM and Hispanic at ten O 8.
  • 32:16And more concerning than that to
  • 32:18me was what I saw in their night
  • 32:21to night bedtime variability.
  • 32:23And so I used this map of time
  • 32:25zones to sort of highlight what I,
  • 32:27what this would be like.
  • 32:28What I'm saying here is that we found
  • 32:31that white children were had on night
  • 32:33to night variability of one hour.
  • 32:34So sleeping in New Haven one night and
  • 32:36you know, Minnesota the next night,
  • 32:38while black and Hispanic children
  • 32:40were sleeping in New Haven one night
  • 32:42and then close to California the next
  • 32:44night and then back to New Haven.
  • 32:46And so when,
  • 32:47if you think about that as an adult,
  • 32:49think that's sort of a powerful message.
  • 32:51And and while sleep health has
  • 32:55not been studied well,
  • 32:57definitely variability,
  • 32:58sleep variability is just beginning
  • 33:00to be understood as a,
  • 33:02an important health variable.
  • 33:07So I'm going to just skip over the,
  • 33:09the models and what we what we did.
  • 33:13But I will say that one thing that
  • 33:15we looked at was I was showing
  • 33:17you the between group differences.
  • 33:19And what we did was then look at
  • 33:23the within group differences,
  • 33:24which I think is important when
  • 33:26you're talking about race,
  • 33:27ethnicity differences.
  • 33:29And what we found was that employment
  • 33:34was significant and housing in
  • 33:37the between group differences.
  • 33:38But when we looked at within
  • 33:41group differences,
  • 33:41an example would be
  • 33:46single parent parents and what we
  • 33:48found was black and white single
  • 33:51parents had the bedtime variability
  • 33:55was there was a high effect size there.
  • 33:58But in the opposite direction where we
  • 34:01found that black single mothers had
  • 34:03children with lower bedtime variability,
  • 34:06some more consistent bedtime,
  • 34:09while single white mothers had a more
  • 34:12variable bedtime or their their children did.
  • 34:16Regarding the biomarker,
  • 34:17this has been a bit more challenging because
  • 34:20of that young age group in which I collected.
  • 34:23It's quite unusual to see that.
  • 34:26And so it kind of begs the question of
  • 34:28just because it can measure something
  • 34:30since sort of struggling with what
  • 34:32to do with some of the results.
  • 34:34We had a lot of extreme values.
  • 34:36I've been working with telemetrics and and
  • 34:43a lab at University of California
  • 34:45Irvine to help me understand that.
  • 34:47That led to a systematic review
  • 34:49of looking at sleep health across
  • 34:52all stress biomarkers in children.
  • 34:54What our results, what we did
  • 34:56find was that from our baseline,
  • 34:58we followed up with these
  • 34:59children a year later.
  • 35:00We did see a bit of a significant
  • 35:05difference with cortisol.
  • 35:08And I'm sorry, not with cortisol.
  • 35:10We did not see with cortisol.
  • 35:11But I will say that that was
  • 35:13really tough to get because I
  • 35:15was asking the parents to do it.
  • 35:17I used the MEMS tab to try to
  • 35:19capture the time, but it wasn't,
  • 35:21it didn't work out so well.
  • 35:22And so I didn't have timing to really
  • 35:25do anything with my cortisol data.
  • 35:27But that said,
  • 35:28Alpha Emily,
  • 35:28we did find to increase over
  • 35:31the course of the year and then
  • 35:33trends for Aisle 6 and some of
  • 35:36the side of clients to decrease.
  • 35:41So just sort of summarizes here.
  • 35:45So some trends as well as
  • 35:48one significant finding.
  • 35:50All this has led to the this
  • 35:52and an R21 that I did with
  • 35:55Doctor Sadler and and Reddicker.
  • 35:57I use that information to develop
  • 36:00a intervention plus sleep well,
  • 36:02be well specifically to address and
  • 36:07help families with young children
  • 36:10to promote sleep health rather than
  • 36:12address sleep problems that exist.
  • 36:16We did a the R21 was a mixed method study,
  • 36:20so we did interview caregivers
  • 36:22and health care providers and
  • 36:25pediatricians as well as families.
  • 36:30What this is my little logo and the materials
  • 36:34are available in English and in Spanish.
  • 36:37I worked with two Early Head Start partners
  • 36:41at LULAC and at the West Haven Child
  • 36:44Development Center and they were both
  • 36:47very interested in in studying sleep.
  • 36:50What I found or including sleep in
  • 36:53their education materials and 170
  • 36:56something pages of the Head Start
  • 36:58performance standards that are federally,
  • 37:01you know, required of the centers.
  • 37:04There is many mention of things
  • 37:07like dental care, nutrition,
  • 37:09safety, exercise,
  • 37:11sleep is mentioned 10 times in the 170
  • 37:16pages and only in the context of safe sleep.
  • 37:19There's nothing in their health promotion
  • 37:22regulations that suggests including sleep and
  • 37:25their required health promotion materials.
  • 37:28And yet the early childcare providers
  • 37:31are telling us about how exhausted
  • 37:34children are coming in to into daycare.
  • 37:38They're coming in late
  • 37:42sometimes, you know, 9/10,
  • 37:4411:00 which makes it very challenging
  • 37:48for the early childcare teachers.
  • 37:52We piloted it. So we had,
  • 37:54we had it's a three-week intervention
  • 37:56that starts with a bedtime routine fit.
  • 37:58And something that we start with
  • 38:00is we have 14 different bedtime
  • 38:03activities that nighttime activities.
  • 38:06And these are all magnets that then I,
  • 38:08I made, I used a cricket machine
  • 38:11to make all of these magnets.
  • 38:13And then they can apply to a
  • 38:14door hanger that I created.
  • 38:16So the families pick what's
  • 38:18important to them.
  • 38:19So they family that pray,
  • 38:21they're family that sing,
  • 38:22they can choose the activities
  • 38:24they want to do at bedtime.
  • 38:25I ask them to choose four to five.
  • 38:27And then every week for three weeks,
  • 38:30every day for three weeks,
  • 38:31the childcare teacher,
  • 38:33there's a different handout that they,
  • 38:35they give to the family.
  • 38:37And then they talk to the
  • 38:40family about topics that are,
  • 38:41that are around the theme of BED,
  • 38:44bedtime, environment and motion,
  • 38:46regulation and duration
  • 38:48and disruptors of sleep.
  • 38:50So they week one we talk about bedtime,
  • 38:53bedtime routines.
  • 38:54Week two we talk about environment
  • 38:56and emotion regulation and
  • 38:57week 31 duration and disorders.
  • 39:00What we found from the families was that
  • 39:04they reported really great feedback.
  • 39:06They, they said things like that.
  • 39:09They felt more connected to their children.
  • 39:12They felt like their child slept better.
  • 39:15They were very happy with the,
  • 39:17with each of them, with all of the materials.
  • 39:22In the pilot, I spoke with a family,
  • 39:25a mother. I didn't.
  • 39:26He came up to me, a single mom of four,
  • 39:29and said to me that she learned so much
  • 39:32from the intervention and that she had.
  • 39:35It was tough in the beginning.
  • 39:37He turned off the television 15 minutes
  • 39:39before he started the bedtime routine.
  • 39:41And at first the children complained,
  • 39:44but then they start to look
  • 39:46forward to reading with her.
  • 39:47And she said that her two year old
  • 39:49who wasn't involved in the study,
  • 39:51she said she,
  • 39:52the two year old started talking
  • 39:53more and that she was attributing
  • 39:55that to her reading the books that I
  • 39:57provided to them and the bedtime kit.
  • 39:59And as she was saying this,
  • 40:00I thought if I never work or do another
  • 40:04research study in my life again.
  • 40:06I've made a difference in this one
  • 40:08family's life and was thrilled.
  • 40:09But at the same time,
  • 40:10I was looking at a box of reach out
  • 40:12and read books inside the the daycare.
  • 40:15And I thought,
  • 40:15I'm not the first person to tell her
  • 40:17that to read to her child that this
  • 40:19is this has such an impact to her.
  • 40:21And she said to me,
  • 40:23just as I was thinking it,
  • 40:24she said, you know,
  • 40:25people have always told
  • 40:26me to read to my children,
  • 40:27but I never thought that I had time.
  • 40:29But reading to them at night
  • 40:31really make has made a difference.
  • 40:33And I thought,
  • 40:34wow,
  • 40:35one thing we just need to do better about is
  • 40:37talking about reading to each
  • 40:38other and actually giving them,
  • 40:39talking to them about when to read
  • 40:41and when and finding out when they
  • 40:43might have opportunity to do that.
  • 40:45And then we did have some,
  • 40:47I know small to medium effect
  • 40:50size of in terms of sleeping.
  • 40:52So this is just sort of a highlight of,
  • 40:56of what we did.
  • 40:59The BED mantra that I was telling
  • 41:02you about what form it is,
  • 41:03that is the prescription
  • 41:07and this pilot was just looking at the
  • 41:10feasibility in the pilot data and I've
  • 41:12now turned have an R1 that will be
  • 41:15reviewed June 10th as a second submission
  • 41:18for this study to continue in multiple
  • 41:21New England Head Start association.
  • 41:23I'm sorry multiple head start
  • 41:25centers across New England.
  • 41:27So everyone keep their fingers
  • 41:28crossed for a good conversation.
  • 41:30June 10th.
  • 41:31And this is just a little highlight
  • 41:34of the teacher training.
  • 41:36So I told you about what the families get,
  • 41:39what the teachers get a training and sleep.
  • 41:42So before they start the intervention,
  • 41:44there's a 6th module training that
  • 41:48developed that is available online.
  • 41:51So they they're 15 minute modules
  • 41:53and my goal is to actually develop
  • 41:56those into CMD credit so that we
  • 41:59can use this also in primary care
  • 42:02because in addition to the RO one,
  • 42:04it's being discussed next week.
  • 42:07Recently with Karen ESA Koi submitted a
  • 42:12Pakori for a comparative effectiveness
  • 42:14trial looking at sleep well be
  • 42:17well will where if we're funded,
  • 42:19we will collaborate with a large
  • 42:22practice based network of primary care
  • 42:25clinics across the country who are
  • 42:28who trained PBS pediatric residents.
  • 42:30And so we will be very excited to
  • 42:32see if we can translate this right to
  • 42:35primary care and come full circle and
  • 42:37and help me get some of these concepts
  • 42:39of parent interaction in into primary care.
  • 42:44And then as I mentioned,
  • 42:45I did submit a grant.
  • 42:47I and I put the title there 'cause
  • 42:49I was just really thrilled with
  • 42:50my cleverness of my title here,
  • 42:52the sleep obesity risk and screen
  • 42:54to children and screens.
  • 42:56I came in second for that grant.
  • 42:58So I did not get funded,
  • 42:59but they gave me public feedback and
  • 43:01I hope to submit that in October.
  • 43:04So I just want to thank my mentors,
  • 43:07Nancy Medicare,
  • 43:08Lois Sandler and John Dion and take
  • 43:11care parties that director of the
  • 43:13sleep clinic and Megan O'Connell
  • 43:15for for their health and these
  • 43:17studies and of course a few doctoral
  • 43:20work both and then amaze.
  • 43:23And Lois Sandler,
  • 43:26thank you.
  • 43:32People have questions or if
  • 43:33we have time for questions or
  • 43:36yes, yes, I think we've got
  • 43:37plenty of time for for questions,
  • 43:38Questions for for Monica.
  • 43:42I want to start out from Sarah
  • 43:44Fitzpatrick too, although minding the
  • 43:46baby like old friends. Thank you.
  • 43:53You know, I would love to
  • 43:55collaborate with anyone too that's
  • 43:56thinking about adding sleep.
  • 43:58Sarah, if anyone's thinking about adding
  • 44:01sleep to their studies or you know,
  • 44:04please contact me. Happy to do help.
  • 44:09Maybe Monica just well,
  • 44:10people are collecting their thoughts.
  • 44:12I, you know, I was wondering if
  • 44:14any of your interventions or if
  • 44:16you've thought about incorporating
  • 44:18grandparents or alternative
  • 44:19caregivers into your interventions.
  • 44:21You know, I'm trying to think,
  • 44:22I'm thinking as someone who
  • 44:23has a nine month at home,
  • 44:24I'm thinking about all the
  • 44:26recommendations and advice that
  • 44:27you get as someone with a new,
  • 44:29with a new baby,
  • 44:30Obviously sleep recommendations
  • 44:31and how you put the child to bed.
  • 44:33They've changed across generations.
  • 44:35And sometimes there is a bit of
  • 44:37a battle of kind of fighting
  • 44:38back against advice that you're
  • 44:39getting from people that may not,
  • 44:41you know, be up to date with
  • 44:43the current best practices.
  • 44:44So I'm just wondering,
  • 44:45is that something that you
  • 44:46thought about or is that something
  • 44:47that's ongoing in the field?
  • 44:50Absolutely. And you know, I should have
  • 44:52said that when in the intervention,
  • 44:54we provide the materials to any
  • 44:56caregiver that has the child overnight
  • 44:58or is involved in night time.
  • 45:00So we always, we ask that and we offer
  • 45:02the materials so that if they're multiple
  • 45:04parents or grandparents involved,
  • 45:06that they're all getting sort
  • 45:08of similar materials.
  • 45:10You know, something clinically that
  • 45:12I do that I think is important
  • 45:14as when I work and sleep,
  • 45:15when I was working at a sleep clinic,
  • 45:17I were giving advice.
  • 45:18I, I listened to what the families,
  • 45:20you know, what they,
  • 45:22what they described to me in a
  • 45:24sleep concern and then have an
  • 45:26idea of what would work and then
  • 45:28would present that to the family.
  • 45:29But I always say to them that
  • 45:32this is one idea.
  • 45:33Do you think this is something
  • 45:35that would work for your family?
  • 45:37Because if not,
  • 45:37pretend like I have a little bag of
  • 45:40tricks next to me and I'll just reach
  • 45:42into my bag and I'll pull out another trick.
  • 45:44I said that because the worst thing
  • 45:46you can do is give you advice that
  • 45:48you will walk out with and be like,
  • 45:50that woman doesn't know what
  • 45:51she's talking about.
  • 45:52That's not going to be helpful
  • 45:54to you and or your child.
  • 45:55So there I,
  • 45:56I don't think it's A1 size fits all.
  • 45:59And I think that some of it is, you know,
  • 46:01we can develop these introversions.
  • 46:03I'll tell you what's evidence based,
  • 46:04but we have to do a better job
  • 46:06of hearing from the families.
  • 46:07What are the limitations or the
  • 46:10cultural beliefs or backgrounds?
  • 46:12Like I said,
  • 46:13we don't have a good questionnaire that
  • 46:16asks about why families are Co sleeping,
  • 46:20because if they're Co sleeping for
  • 46:23reaction as a reactional Co sleeping
  • 46:25or intentional or cultural or SDS,
  • 46:28those are those are different.
  • 46:30You know that the background is
  • 46:32important before we understand it.
  • 46:34And so these studies that
  • 46:36talk about closely things,
  • 46:37but they haven't really asked why.
  • 46:40I think it's it's not really
  • 46:42appropriate to make any judgments,
  • 46:45you know, or that we can really
  • 46:47determine what's what's healthy or not.
  • 46:50So I don't know if that didn't,
  • 46:52I would just say that got
  • 46:53to answer your question,
  • 46:54very open to that.
  • 46:55But I think a lot of it's going
  • 46:57to come in training that putting
  • 46:58that into the training materials
  • 47:00for whether it's the teachers
  • 47:01that are delivering the materials
  • 47:03or the healthcare providers that
  • 47:05are delivering the materials.
  • 47:06And even though I used a little
  • 47:08prescription pad not being so
  • 47:09prescriptive in our advice.
  • 47:12Yeah, makes good sense.
  • 47:14And have you noticed something
  • 47:15I've been very surprised about
  • 47:17is seeing advertisements for
  • 47:19sleep aids for children.
  • 47:21And so melatonin based sleep aids.
  • 47:23It is something that you're
  • 47:24seeing an increase in.
  • 47:25Is this something that you're
  • 47:27assessing and what's your advice
  • 47:28and feedback on on these aids?
  • 47:31Oh, melatonin right now is a huge
  • 47:34topic of of I know, you know,
  • 47:35very unregulated, very commonly
  • 47:39used in any to send to a pharmacy.
  • 47:42And it's always like at the end cap
  • 47:44of all these sleep aids and they
  • 47:47market them to you know quality sleep.
  • 47:49And I think we we definitely
  • 47:51don't know enough.
  • 47:52We are coming out the IPSA that I
  • 47:55mentioned International Pediatric
  • 47:56Sleep Association on the board there.
  • 47:59We're coming out with a statement
  • 48:01about melatonin use,
  • 48:02but the statement is not going
  • 48:04to include we don't have good
  • 48:07evidence about the use of them.
  • 48:09I think they are very useful
  • 48:11and we commonly use them and
  • 48:14neurodiverse patient, but I,
  • 48:16I think that we want to move
  • 48:19away from just sort of a blanket
  • 48:21recommendation as a Band-Aid and not as
  • 48:26really picking up and following up.
  • 48:28Was that effective?
  • 48:28So if you're talking about
  • 48:30melatonin in particular,
  • 48:31that's, that's one that,
  • 48:34and then there's the, you know,
  • 48:36$1800 new bassinet that, you know,
  • 48:43these are great and if you
  • 48:44can afford them, but it's,
  • 48:45I don't think that's the only answer.
  • 48:47And I think we have some work to do on
  • 48:50avoiding shaming families on social media.
  • 48:54I, I've had many conversations with
  • 48:58families who are parents that talk
  • 49:00to me about how awful it is to,
  • 49:03to do a cried out method and
  • 49:06how babies could not cry.
  • 49:08I recently had someone tell
  • 49:09me that they shouldn't,
  • 49:11babies shouldn't cry for even a minute,
  • 49:12but it does brain damage to them.
  • 49:15It increases their cortisol levels.
  • 49:17And he writes books on this and that.
  • 49:21It's all about attachment.
  • 49:23And I'm breaking attachment.
  • 49:25And she speaks internationally
  • 49:27and nationally on top of this.
  • 49:29So it was an interesting conversation
  • 49:30at my son's graduation with a
  • 49:32mother that caused graduation with
  • 49:34a mother that my son thought, well,
  • 49:35you two are gonna have so much in common.
  • 49:37I really.
  • 49:39Oh, I thought you were talking to so and so.
  • 49:41I knew you guys would get along.
  • 49:42I said maybe we'll talk about that later.
  • 49:46You're a little different in our opinion.
  • 49:53Maybe leave that there. Oh, please, Ansley.
  • 49:58So just a quick question.
  • 50:02I love it. But the, the, the main,
  • 50:04the main question that I have is I
  • 50:07know that you focused on families and,
  • 50:10and young children.
  • 50:12For the longest time, I,
  • 50:13I identified as a parent of young children,
  • 50:16but now I have to bite the
  • 50:18bullet and acknowledge that my
  • 50:19kids are becoming teenagers.
  • 50:21So, but that being said,
  • 50:26would this be something that
  • 50:29could be feasibly done with
  • 50:31adolescent or teen population?
  • 50:33And I'm thinking what the,
  • 50:36the thought that's coming to
  • 50:38my mind is mood disorders.
  • 50:41Usually one of the core symptoms is
  • 50:45alterations in their sleep patterns.
  • 50:48And we know that for a fact,
  • 50:50adolescents start to have changes
  • 50:52in their sleep patterns just
  • 50:54because they're adolescents,
  • 50:55right, developmentally.
  • 50:56So it would be really,
  • 50:58really interesting to kind of
  • 51:01map out kind of like the sleep
  • 51:04patterns of depressed kids
  • 51:06versus the sleep patterns of non
  • 51:09depressed kids kind of coping for,
  • 51:11for, you know,
  • 51:13different things.
  • 51:15And one of the things that we've
  • 51:17been seeing in our in our adolescent
  • 51:20population is that a lot of them are
  • 51:23self medicating for sleep issues.
  • 51:26So either using marijuana or actually
  • 51:30even using alcohol to help sleep.
  • 51:33And you're talking about 1415 year olds,
  • 51:36so I don't know if if that would be
  • 51:39something I can send you an e-mail and
  • 51:41we can try to figure something out.
  • 51:44But
  • 51:44Oh yeah, I mean,
  • 51:46you definitely are speaking my language.
  • 51:48I would say the answer for the first
  • 51:50part with Doctor Owens at Harvard.
  • 51:52I'm consulting on a intervention she's
  • 51:55developing for school age children.
  • 51:57And so she and I are talking about
  • 51:59what I'd love to do is I actually want
  • 52:01to create the program from prenatal.
  • 52:03So just like we have breastfeeding
  • 52:06classes for prenatal families,
  • 52:07I think we should have sleep
  • 52:09preparation and talk about the 1st.
  • 52:12I mean, I feel like it would be very
  • 52:14empowering to talk to a new parent
  • 52:16and help them and let them know that
  • 52:18there's only two stages of sleep and
  • 52:19for the first two or three months.
  • 52:21So actually the whole confusion
  • 52:22the night and they hear these
  • 52:24things about confusing their night
  • 52:25and the day it it doesn't it.
  • 52:28That's powerful information.
  • 52:29So I'd love to do it from
  • 52:31prenatal through school aid.
  • 52:32Adolescence are a unique set of
  • 52:36other set of circumstances and
  • 52:40it'd be a whole nother talk.
  • 52:41But I will just highlight a couple things.
  • 52:43You really hit the nail on the head when
  • 52:45you said about the the change in pattern.
  • 52:48And a lot of families don't
  • 52:50understand that adolescence,
  • 52:52their Physiology changes that they
  • 52:55become their bedtime if their
  • 52:58circadian rhythm shifts to a bedtime
  • 53:00that would be closer to 10:50 PM.
  • 53:04And so that becomes very challenging
  • 53:07when schools are starting at
  • 53:107:15 AM and they're expected to
  • 53:12be in the classroom at 7:15 AM.
  • 53:15And which means like in my neighborhood,
  • 53:17they were picking up for school
  • 53:18at 6:00 AM on the bus.
  • 53:20We recommend the American Academy
  • 53:23Pediatrics that and sleep society that that
  • 53:26I'm sorry that school starts to be 8:30.
  • 53:29And in Colorado they've done some
  • 53:30great work where they have shifted
  • 53:32the school start time and they have
  • 53:35seen a reduction in adolescent
  • 53:37depression and in suicidality.
  • 53:40And so this is what so I think
  • 53:43we all would say,
  • 53:44but then we why we should
  • 53:45just be changing this.
  • 53:47It becomes a very complex because in
  • 53:49New Haven the issue is that to have
  • 53:52the younger children go into school
  • 53:54earlier means they get off the bus
  • 53:57earlier and they don't have families,
  • 53:59don't have the child care,
  • 54:00so the older children have
  • 54:01to get off the bus earlier.
  • 54:03And Greenwich,
  • 54:04the issue that they've been resistant
  • 54:06about late school start time is
  • 54:08because the teachers can't afford
  • 54:10to live in Greenwich and so they
  • 54:12have resisted it because they
  • 54:13don't want to be in the traffic.
  • 54:15It would change the traffic pattern.
  • 54:16So the the reasons for each town
  • 54:18and why they don't want to do the
  • 54:21delayed school start time becomes
  • 54:23is very unique and challenging.
  • 54:25But the literature and the
  • 54:27evidence is there that these kids,
  • 54:29you can't get the adequate amount
  • 54:31of sleep if your bedtime Physiology
  • 54:34is 10:50 PM and you have to get
  • 54:37up at 5:30 to do your hair,
  • 54:40eat your breakfast and get ready
  • 54:42for school.
  • 54:44So there's a lot of important work.
  • 54:46And oh, and one last thing,
  • 54:47sorry about the alcohol marijuana.
  • 54:49The keynote address here at the
  • 54:51sleep conference was actually
  • 54:53I was took a picture of it
  • 54:55because alcohol and marijuana,
  • 54:56both marijuana has not been tested.
  • 54:59We don't have a lot of studies on it,
  • 55:01but it's we know for a fact that alcohol
  • 55:04actually makes your sleep worse.
  • 55:07So while it might help them fall asleep,
  • 55:08their sleep quality is very
  • 55:11reduced and they it's a reduction
  • 55:13in flow wave sleep and REM sleep.
  • 55:15And it looks like marijuana is also the same,
  • 55:18which I was a little surprised about
  • 55:20because you hear a lot of people
  • 55:21talking about taking gummies and
  • 55:23things like that to help them to sleep.
  • 55:24But we definitely need more data on
  • 55:31my son during COVID had a his first job.
  • 55:35When I feel you, by the way,
  • 55:36because my kids are now adults.
  • 55:38They're 19 and 22, which is going to
  • 55:40make Nancy fall off her chair and Sarah,
  • 55:43but like they're they're now adults.
  • 55:45But when he was 16 was during COVID
  • 55:48working at CVS and I found a bottle
  • 55:51of 10 milligram melatonin CVS brand
  • 55:53on his night stand and I lost my mind.
  • 55:56And then I called myself
  • 55:58and mentalized and said,
  • 55:59tell me what you're doing this.
  • 56:01And I said it would never recommend
  • 56:0310 milligrams, never CVS brand.
  • 56:05What were you thinking?
  • 56:06So with the bottle said it
  • 56:07will help you sleep better.
  • 56:08So since he was only going to
  • 56:10sleep for five or six hours,
  • 56:11he thought he could stay up later,
  • 56:13have a shorter period of time
  • 56:15to have better quality sleep
  • 56:16and but totally misunderstood.
  • 56:18And then went on to tell me that
  • 56:20the bottle was returned by a
  • 56:21customer and they are not allowed
  • 56:23to put it back on the shelf.
  • 56:24And so he, he didn't buy it, he just took it.
  • 56:27So now I was dealing with taking 10
  • 56:30milligrams CVS brand returned bottle.
  • 56:33Smart kid and Nancy will know
  • 56:34exactly which fun I'm talking about.
  • 56:40Adolescent risk taking. Yes.
  • 56:43Yeah. The way they think is a
  • 56:44whole different, you know it,
  • 56:46it just surprises you every time.
  • 56:48I'm like, what
  • 56:48did you think?
  • 56:51Monica? Thank you again
  • 56:52for joining us today.
  • 56:53For Grand Rat especially,
  • 56:54it's just such short notice.
  • 56:56That was a really interesting talk
  • 56:57and I guess probably sparked a
  • 56:58lot of ideas for our community.
  • 57:00So anyone who is interested
  • 57:01in collaborating with Monica,
  • 57:02please feel free to reach out
  • 57:04and thank you once again.
  • 57:06Thank you, Sir. Thanks for
  • 57:08having me everyone. Bye bye.