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Yale School of Medicine researchers explore the many functions of mitochondria—and how their malfunction can contribute to a broad range of diseases.

People who got the injection, retatrutide, lost 28 percent of their body weight on average after 80 weeks, Eli Lilly said.

In a clinical trial, the new weight-loss medication retatrutide led to "clinically meaningful weight reduction," with the highest dose linked to a 30% reduction in average body weight.

Identifying children with early signs of type 1 diabetes makes a difference to their health. A new study suggests wider screening is effective.

Jennifer Sherr, MD, PhD, professor of pediatrics (endocrinology), will be recognized at the kickoff of the 2026 American Diabetes Association annual meeting with the W!LD Inspire Award.

Before the new obesity drugs came on the market, almost no one used the term food noise. If researchers can clarify the source of this inner buzz and what makes it go away, that could lead to a clearer understanding of what causes obesity in the first place.

It is an epidemic,” said Jennifer Sherr, MD, professor of pediatrics and medical director of the pediatric diabetes program at Yale University School of Medicine, New Haven, Connecticut. When asked to explain what makes it an epidemic — uncontrolled glycemic levels, more youngsters being diagnosed — she replied with “All of the above.”

“We’ve never seen weight loss at this level before,” says Ania Jastreboff, MD, PhD, the director of the Yale Obesity Research Center at the Yale School of Medicine, who has been involved in research on the drug.