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COVID virus clears from placenta weeks after maternal infection, study suggests

The virus that causes COVID-19 does not appear to linger in placental tissue after a pregnant patient recovers from acute infection, according to a case-control study published this week in JAMA Network Open. The findings suggest that placental infection is unlikely in the weeks and months after illness, even in cases with adverse outcomes. “Our motivation for doing the study was to see if there was 'long COVID' in the placenta,” Harvey J. Kliman, MD, PhD, director of the Reproductive and Placental Research Unit at Yale School of Medicine and senior study author, told CIDRAP news in an email. “This is one of the scariest aspects of COVID: long COVID leading to chronic brain issues.” “We just didn’t know if this could also happen in the placenta, which is a magnet for the SARS-CoV-2 virus (because the placenta is covered with ACE2 [angiotensin-converting enzyme 2], the receptor for the spike protein of the virus),” he added. “So we thought it was necessary to look at this issue.”

Source: Center for Infectious Disease Research and Policy
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