E. Jennifer Edelman, MD, MHS, AAHIVS
Professor of Medicine (General Medicine)Cards
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Associate Professor on Term, Social and Behavioral Sciences
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General Internal Medicine
PO Box 208056
New Haven, CT 06520-8025
United States
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Associate Professor on Term, Social and Behavioral Sciences
Contact Info
General Internal Medicine
PO Box 208056
New Haven, CT 06520-8025
United States
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Associate Professor on Term, Social and Behavioral Sciences
Contact Info
General Internal Medicine
PO Box 208056
New Haven, CT 06520-8025
United States
About
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Titles
Professor of Medicine (General Medicine)
Associate Professor on Term, Social and Behavioral Sciences
Biography
E. Jennifer Edelman, MD, MHS is a Professor of Medicine (General Internal Medicine) and Public Health (Social and Behavioral Sciences) at Yale University. Certified as an internist, HIV specialist, and in Addiction Medicine, she provides clinical care at the Yale New Haven Hospital Center for Infectious Disease treating individuals with HIV and substance use disorders. She is Director of the Yale Center for Interdisciplinary Research on AIDS Clinical and Health Services Research Core, co-Director of Education at the Yale Center for Clinical Investigation, and Associate Director of the National Institute on Drug Abuse (NIDA)-funded Research in Addiction Medicine Scholars (RAMS) Program. Funded by the National Institutes of Health, her research over the past 15+ years has focused on understanding and addressing harms of substance use among individuals with and at substantial risk for HIV. She has experience applying a range of methodologies – including observational, interventional and implementation science-based approaches – and collaborating with diverse clinical, community, and public health-based partners. She enjoys mentoring trainees and junior faculty.
Appointments
General Internal Medicine
ProfessorPrimarySocial and Behavioral Sciences
ProfessorSecondary
Other Departments & Organizations
- Addiction Medicine Fellowship Program
- AIDS Care Program
- Edelman Lab (Phoenix Lab)
- General Internal Medicine
- Internal Medicine
- Program in Addiction Medicine
- R3EDI Implementation Science Hub
- Social and Behavioral Sciences
- Yale Center for Health & Learning Games
- Yale Medicine
- Yale New Haven Health System
- Yale Ventures
- Yale-Drug use, Addiction, and HIV prevention Research Scholars (DAHRS)
- Yale-UPR Integrated HIV Basic and Clinical Sciences Initiative
Education & Training
- MHS
- Yale University
- Clinical Scholar
- Yale School of Medicine
- Chief Resident
- Yale-New Haven Hospital
- Residency
- Yale-New Haven Hospital
- Intern
- Yale-New Haven Hospital
- MD
- Columbia University
- BS
- Cornell University, Human Development and Family Studies; and Human Biology, Health
Research
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Overview
Medical Research Interests
ORCID
0000-0002-9375-0489
Research Projects
Prescription Stimulants for Attention-Deficit/Hyperactivity Disorder (ADHD)
General Internal Medicine / , parent organization of Edelman Lab (Phoenix Lab)Promoting Retention in Opioid Treatment among Women Experiencing Intimate Partner Violence: A Novel Stepped Care Model Targeting PTSD
General Internal Medicine / , parent organization of Edelman Lab (Phoenix Lab)Alcohol use and geriatric syndromes among specific minoritized groups living in socioeconomic disadvantage
General Internal Medicine / , parent organization of Edelman Lab (Phoenix Lab)Informing and promoting Shared decision making for HIV Prevention and Alcohol Reduction: Engaging Diverse Veterans to Refine and Pilot a Decision Aid (SHARE Study)
General Internal Medicine / , parent organization of Edelman Lab (Phoenix Lab)Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications, and CBT4CBT: A randomized clinical trial in a diverse patient population
General Internal Medicine / , parent organization of Edelman Lab (Phoenix Lab)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
David Fiellin, MD
Amy Justice, MD, PhD
Jeanette Tetrault, MD, FACP, FASAM
Gail D'Onofrio, MD, MS
Kathryn Hawk, MD, MHS
James Dziura, MPH, PhD
Publications
2026
Best Practices for Hospital-Based Initiation of Medications for Opioid Use Disorder
Cohen S, Straus E, Fiellin D, Pomeranz J, Suzuki J, Tetrault J, Weimer M, Edelman E, Joudrey P. Best Practices for Hospital-Based Initiation of Medications for Opioid Use Disorder. JAMA Network Open 2026, 9: e2611514. PMID: 42096208, DOI: 10.1001/jamanetworkopen.2026.11514.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHospital-based initiativesOpioid use disorderSurvey studyMethadone initiationAdvanced practice cliniciansHospital-based physiciansRAND/UCLA Appropriateness MethodOpioid withdrawalUse disorderBuprenorphine initiationHospitalized patientsInitiation of medicationPractice locationTreatment of opioid withdrawalSpecialty cliniciansMain OutcomesDelphi processLow-dose initiationAddiction cliniciansSynthetic opioidsRobust researchBoard certificationNational expertsExpert consensusAddiction medicinePeer Support for Whole Health: R esults from a mixed methods two phase pilot study
Johnson E, Possemato K, True G, Edelman E, Wade M, Sedotto R, Maisto S, Chinman M. Peer Support for Whole Health: R esults from a mixed methods two phase pilot study. Journal Of Behavioral Medicine 2026, 1-12. PMID: 41961357, DOI: 10.1007/s10865-026-00656-4.Peer-Reviewed Original ResearchConceptsWhole healthVeterans Health AdministrationPeer supportPsychosocial functioningRandomized clinical trialsEligible veteransPatient satisfactionPilot randomized clinical trialFunctions of peer supportPrimary care settingBehavioral health screeningWaitlist control armBehavioral health concernsPatient satisfaction scoresStudy related adverse eventsConclusionsPeer supportLarger-scale trialsPrimary careWellness goalsIntervention retentionIntervention adaptationIntervention armCare settingsPermuted block randomizationWaitlist armClinicians’ Perspectives on Implementing Contingency Management to Promote Parental Smoking Cessation in Routine Infant Care
Flom J, Camenga D, Shabanova V, McCollum S, Sandoval J, Chairuengjitjaras P, Forray A, Ledgerwood D, Edelman E, Sharifi M. Clinicians’ Perspectives on Implementing Contingency Management to Promote Parental Smoking Cessation in Routine Infant Care. Academic Pediatrics 2026, 103301. PMID: 41871754, DOI: 10.1016/j.acap.2026.103301.Peer-Reviewed Original ResearchAltmetricConceptsFramework analysisSmoking cessationEvidence-based smoking cessation interventionsPediatric cliniciansImplementation strategiesCaregiver behavior changePediatric primary careQualified health centersAnalysis of interview transcriptsParental smoking cessationAwareness of CMSecondhand smoke exposureSmoking cessation interventionsPersonal smoking historyViews of caregiversContingency managementRoutine infant carePositive viewPrimary careSupport caregiversThematic saturationCessation interventionsClinicians' attitudesImplementation researchClinician perspectivesEmergency Department–Initiated Buprenorphine for Opioid Use Disorder
D’Onofrio G, Herring A, Hawk K, Perrone J, Cowan E, McCormack R, Dziura J, Matthews A, Pantalon M, Owens P, Martel S, Coupet E, Lofwall M, Walsh S, Edelman E, Carpenter J, Strout T, Baumann M, Anderson E, Barrett T, Dorey A, Taillac P, Cochran G, Crandall C, Wilson J, Manteuffel J, Cole J, Whiteside L, Jones C, Samuels E, Huntley K, Fiellin D, Schwarz E, Williamson B, Lee J, Lanter P, Pope J, King A, Stolbach A, Jennings L, Chang B, Kim H, Ketcham E, Wightman R, D’Orazio J, Moore P, Lynch M, Sullivan R, O'Connor P. Emergency Department–Initiated Buprenorphine for Opioid Use Disorder. JAMA: The Journal Of The American Medical Association 2026, 335: 948-960. PMID: 41670966, PMCID: PMC12895321, DOI: 10.1001/jama.2025.27019.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdministration, SublingualAdultBuprenorphineDelayed-Action PreparationsEmergency Room VisitsFemaleFentanylHumansInjections, SubcutaneousMaleMiddle AgedNarcotic AntagonistsOpiate OverdoseOpiate Substitution TreatmentOpioid-Related DisordersPatient SatisfactionSelf AdministrationSubstance Withdrawal SyndromeConceptsClinical Opiate Withdrawal ScaleClinical Opiate Withdrawal Scale scoreExtended-release buprenorphineOpioid use disorderUse disorderIllicit opioid useSublingual buprenorphineDays of illicit opioid useOpioid use disorder treatmentCraving scoresTreatment engagementDisorder treatmentExtended-releaseOpiate Withdrawal ScaleLevels of withdrawalEmergency departmentInjectable buprenorphineUntreated opioid use disorderOpioid useSelf-AdministrationPrecipitated withdrawalWithdrawal ScaleEmergency department-initiated buprenorphineDay 7Multicenter Randomized Clinical TrialFood insecurity and COVID-19-related experiences among people with HIV: A mixed methods analysis and conceptual framework
Harsono D, Sklar K, Silver M, Frederick M, Villanueva M, Edelman E, Yager J. Food insecurity and COVID-19-related experiences among people with HIV: A mixed methods analysis and conceptual framework. PLOS ONE 2026, 21: e0342667. PMID: 41678510, PMCID: PMC12900320, DOI: 10.1371/journal.pone.0342667.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsExperiences of food insecurityFood insecurity experiencesFood insecurityFree-text survey responsesHIV care engagementPoor health outcomesLikelihood of chronic diseaseHIV care settingsFocus group transcriptsEvidence-based interventionsLevels of food insecurityCOVID-19-related experiencesCOVID-19 pandemicSocial-ecological frameworkEthnic minority groupsCare engagementHealth disparitiesReceive careCare settingsGroup transcriptsHealth outcomesClinical staffSociodemographic factorsHIV clinicFocus groupsClinical Pharmacists, Medications, and Contingency Management for Targeting Smoking in HIV Clinics
Edelman E, Deng Y, Dziura J, Nahum-Shani I, Weiss J, Aoun-Barakat L, Bold K, Harsono D, Mistler C, Payne E, Aiudi S, Sigel K, Yager J, Ledgerwood D, Bernstein S. Clinical Pharmacists, Medications, and Contingency Management for Targeting Smoking in HIV Clinics. JAMA Network Open 2026, 9: e2560593. PMID: 41758512, PMCID: PMC12949440, DOI: 10.1001/jamanetworkopen.2025.60593.Peer-Reviewed Original ResearchThis study investigates clinical pharmacist-led nicotine replacement therapy (NRT) with contingency management (CM) for reducing smoking in people with HIV, showing CM significantly improved abstinence at 12 weeks and reduced smoking when added after NRT nonresponse.The association between long-term opioid therapy and composite infection-related dental outcomes
Black A, Gordon K, Dziura J, Barry D, Crystal S, Edelman E, Gibson G, Hamilton M, Jurasic M, Li Y, Marshall B, Skanderson M, Suda K, Becker W. The association between long-term opioid therapy and composite infection-related dental outcomes. PLOS ONE 2026, 21: e0341361. PMID: 41628103, PMCID: PMC12863492, DOI: 10.1371/journal.pone.0341361.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsFood and Drug AdministrationDental coverageDental outcomesLong-term opioid therapyComprehensive dental coveragePartial opioid agonistFollow-up timeCox regression modelsOpioid use disorderAssociated with riskNational cohort studyPatient-provider discussionsOpioid therapyOpioid agonistsOpioid analgesicsChronic painDental diseaseMultivariate regression modelCohort studyDrug AdministrationPatientsUse disorderRegression modelsUnclear generalizabilityResidual confoundingInvestigator- and Site-Level Outcomes of Participation in an ED-Based Clinical Trial
Carpenter J, Hawk K, Herring A, Cowan E, McCormack R, Owens P, Martel S, Edelman E, Huntley K, Perrone J, D’Onofrio G, Schwarz E, Williamson B, Lee J, Jones C, Lanter P, Pope J, King A, Carpenter J, Whiteside L, Duber H, Miner J, Cole J, Manteuffel J, Miller J, Herring A, Stolbach A, Baumann M, Strout T, Jennings L, Chang B, Kim H, Perrone J, Jang D, Ketcham E, Samuels E, Wightman R, Anderson E, Wilson J, D’Orazio J, Moore P, Crandall C, Cotton J, Lynch M, Cochran G, Madsen T, Taillac P, Dorey A, Sullivan R, Barrett T, Wilson A, Hawk K. Investigator- and Site-Level Outcomes of Participation in an ED-Based Clinical Trial. JAMA Network Open 2026, 9: e2555847. PMID: 41661598, PMCID: PMC12887738, DOI: 10.1001/jamanetworkopen.2025.55847.Peer-Reviewed Original ResearchCitationsAltmetricPenicillin Allergy Labels are Associated with Carbapenem/Monobactam Antibiotic Utilization among Patients Undergoing Hematopoietic Stem Cell Transplants
Belmont A, Reynolds J, Stone C, Valente M, Dziura J, Gehan D, Malinis M, Phillips E, Sarpong D, Seropian S, Edelman E. Penicillin Allergy Labels are Associated with Carbapenem/Monobactam Antibiotic Utilization among Patients Undergoing Hematopoietic Stem Cell Transplants. The Journal Of Allergy And Clinical Immunology 2026, 157: ab108. DOI: 10.1016/j.jaci.2025.12.320.Peer-Reviewed Original Research
2025
Implementation facilitation improves readiness for emergency department-initiated buprenorphine to treat opioid use disorder
Strout T, Dziura J, Barrett T, Cowan E, Hawk K, Herring A, Manteuffel J, Martel S, Owens P, McCormack R, Perrone J, Fiellin D, D'Onofrio G, Edelman E. Implementation facilitation improves readiness for emergency department-initiated buprenorphine to treat opioid use disorder. Journal Of Substance Use And Addiction Treatment 2025, 209845. PMID: 41354305, PMCID: PMC12826104, DOI: 10.1016/j.josat.2025.209845.Peer-Reviewed Original ResearchConceptsImplementation facilitatorsEmergency department-initiated buprenorphineOpioid use disorderED readinessRandomized clinical trialsMedical directorsED medical directorsSite principal investigatorsUse disorderTreatment of opioid use disorderNursing supportAddress barriersLikert scale ratingsPost-enrollmentLinear regression modelsPre-enrollmentInsurance coverageTreatment availabilityClinical trialsRegression modelsFacilitationBuprenorphineReadinessTime pointsScale ratings
Clinical Trials
Current Trials
Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE)
IRB ID2000030586RolePrincipal InvestigatorPrimary Completion Date02/28/2023Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
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Activities
activity Yale Diversity Committee
07/01/2021 - PresentCommitteesChairpersonDetailsCo-chair of the Department of Medicine's Diversity Committee Funding and Resource subcommittee
Honors
honor Dr. Robert A. Savitt & Dr. George D. McCormack Award
01/01/2022Regional AwardColumbia University, New York, New YorkDetailsUnited Stateshonor Lipkin Award Finalist*, Society of General Internal Medicine National Annual Meeting, Oral Presentation
04/21/2021National AwardSociety of General Internal Medicine (SGIM), Virtual (*Mentor)DetailsUnited Stateshonor Lipkin Award Finalist*, Society of General Internal Medicine National Annual Meeting, Oral Presentation
05/08/2019National AwardSociety of General Internal Medicine (SGIM), Washington, DC (*Mentor)DetailsUnited Stateshonor Veterans Affairs Locally-Initiated Project Funding Award (“Prescription Opioid Tapering: Trajectories Among Men and Women Veterans”)
01/01/2019Yale University AwardUS Department of Veterans Affairs, West Haven, CTDetailsUnited States
Clinical Care
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Overview
E. Jennifer Edelman, MD, MHS, specializes in HIV and addiction medicine. She provides patient care for HIV/AIDS and its associated complications, such as HIV-associated myopathy, dementia, and neurocognitive disorder.
In addition to her clinical work in HIV care, Dr. Edelman’s research examines substance use disorder treatment in HIV clinics, emergency department-initiated buprenorphine programs, and alcohol reduction interventions for people with HIV.
A recipient of the New England Society of General Internal Medicine Award for Excellence in Clinical Investigation and the Society of General Internal Medicine Lawrence Linn Award, her research has been supported by grants from the National Institutes of Health, the National Institute on Alcohol Abuse and Alcoholism, and the National Cancer Institute.
Dr. Edelman is a professor of medicine at Yale School of Medicine.
Clinical Specialties
Fact Sheets
Human Immunodeficiency Virus (HIV)
Learn More on Yale MedicineOpioid Use Disorder
Learn More on Yale MedicineStimulant Use Disorder
Learn More on Yale MedicineAlcohol Use Disorder
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Board Certifications
Addiction Medicine (Internal Medicine)
- Certification Organization
- AB of Addiction Medicine
- Latest Certification Date
- 2024
- Original Certification Date
- 2014
HIV Specialist
- Certification Organization
- American Academy of HIV Medicine
- Latest Certification Date
- 2021
- Original Certification Date
- 2013
Yale Medicine News
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News
- May 28, 2026
A Researcher’s Perspective: How YCCI Supports High-Quality Clinical Research
- May 07, 2026
Addiction Experts Develop Best Practices for Treating Opioid Use Disorder in the Hospital
- May 06, 2026
Michelle Colon and June Weiss Honored with 2026 Internal Medicine Service Excellence Awards
- March 02, 2026
Integrating Tobacco Treatment in HIV Care
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Contacts
General Internal Medicine
PO Box 208056
New Haven, CT 06520-8025
United States
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.