Neuroinfectious Diseases

The Yale School of Medicine brings together faculty dedicated to the study of neuroinfectious diseases. This multidisciplinary team works to advance understanding of infections that impact the nervous system. Our group conducts a wide range of basic science, clinical, and epidemiologic research, often in collaboration with other institutions. In addition to research, we provide specialized consultation and clinical care for patients with complex neurological infections.

Yale investigators are involved in many NIH-funded studies focused on neuroinfectious diseases. Current research explores the neurological effects of conditions such as HIV, COVID-19, tick-borne illnesses, and malaria. These programs offer robust research training opportunities for both predoctoral and postdoctoral trainees interested in this evolving field. We are actively enrolling participants in translational research studies examining HIV, COVID-19, syphilis, and other conditions that affect the brain.

Faculty specializing in Neuro-HIV are internationally recognized leaders in understanding how HIV affects the brain. Our team has made important contributions to the field of HIV neurology, with the ultimate goal of improving the quality of life and neurological health of individuals living with HIV.

Physicians at the Yale Neuro-Infectious Diseases Clinic treat patients with neurological complications related to systemic infections such as HIV, tuberculosis, and syphilis, as well as those with primary neurological infections like meningitis and brain abscesses. The clinic is staffed by infectious disease specialists and neurologists with advanced training in infectious diseases and operates within the Yale Center for Infectious Diseases. Patients may also have opportunities to participate in ongoing clinical research studies.

Our team is dedicated to delivering compassionate and comprehensive care to individuals living with HIV who develop neurological complications, such as cognitive impairment, neuropathy, brain infections, and conditions involving the spinal cord or muscles.

Second year fellows in infectious disease may choose to concentrate in neuro-infectious diseases. The primary goal of this program is to provide second year ID fellows with opportunities for academic development and research in neurological infections, and to provide exposure to clinical neuroinfectious diseases. Faculty from Yale Neuro-Infectious Diseases also provide teaching lectures to medical students and residents on topics related to neurological infections.