Non-Hodgkin's Lymphoma, Phase III
A Phase 3 Randomized Double-Blind Multicenter Study of Sonrotoclax Plus Zanubrutinib Versus Placebo Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma
Volunteers
Health Professionals
What is the purpose of this trial?
The goal of this study is to compare how well sonrotoclax plus zanubrutinib works versus zanubrutinib plus placebo in treating adults with relapsed/refractory (R/R) mantle cell lymphoma (MCL). This study will also look at the safety of sonrotoclax plus zanubrutinib versus zanubrutinib plus placebo.
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Principal Investigator
Sub-Investigators
- Agatha Hecht
- Alessia Donadio, MD
- Alexis Walker, PA
- Armand Russo, MD
- Catherine Wei, MD
- Clarice Grens, APRN
- D. Barry Boyd, MD, MS
- Daniel Boxer, MD
- Elizabeth Gaa, APRN
- Emily Kopas, APRN, OCN
- Ethan Kohn, PA
- Francine Foss, MD
- Iris Isufi, MD
- Jadwiga Kretowicz, APRN
- Jose Morales-Marin
- Justine Boulanger-Parzych, APRN
- Kayla Martello
- Kristen Hoxie, PA
- Larisa Fleysher, APRN
- Laura Sabourin
- M. Sung Lee, MD
- Madeline Santiago
- Sara Anastasio, APRN, RN
- Scott Huntington, MD, MPH, MSc
- Stuart Seropian, MD
- Syed Ali
- Tarsheen Sethi, MD, MSc
- Vidya Kesavan
- Virginia Syombathy, APRN
- Yifei Zhang, MD
- Last Updated05/17/2026
- Study IRB#2000039878