Latest Research Findings

This study investigates how PI3K enables pancreatic cancer cells to resist KRAS inhibitors by activating wild-type RAS signaling, suggesting combined PI3K-KRAS targeting as a therapeutic strategy.

This study investigates how dietary fat composition influences pancreatic cancer, showing that monounsaturated fats promote tumor growth while polyunsaturated fats reduce risk by enhancing ferroptosis sensitivity.

This study investigates biomarkers in renal cell carcinoma, showing tumor PD-L1 expression predicts better survival with immunotherapy, while neutrophil markers highlight sarcomatoid/rhabdoid tumor immune environments.

This study investigates advances in minimally invasive therapies for lung cancer, showing improved tumor targeting, safety, and potential benefits when combined with immunotherapy and chemotherapy.

This study investigates PF-08634404, a dual-action antibody targeting PD-1 and VEGF, combined with chemotherapy for extensive-stage small cell lung cancer to improve survival outcomes.

This study investigates sotorasib's real-world effectiveness in KRAS G12C-mutated lung cancer with brain metastases, showing intracranial activity and survival outcomes consistent with clinical trials.