For many years, inflammation was considered one of medicine’s chief enemies. Experts viewed it as a side effect of illness and injury, a negative byproduct of the body’s efforts to heal. One managed and banished it whenever possible.
Throughout his career at Yale, Joseph E. Craft, MD, HS ’80, FW ’85, has studied autoimmunity, specifically systemic lupus erythematosus.
For followers of popular science news—or of the latest diet craze—the term “intermittent fasting” is decidedly trending. Each new mention of the eating plan brings with it more revelations about the health benefits it could offer.
In ancient times physicians extracted from the bark of the willow tree a substance—salicylic acid—that reduced fevers, inflammation, and pain. By the mid-19th century, a French chemist had mixed the acid with acetyl chloride to form acetylsalicylic acid, the compound that Bayer marketed in 1899..
Autoimmune diseases—such as Sjögren’s, lupus, and rheumatoid arthritis—can occur together. Here’s what this means for treatment.
The body survives infection in one of two ways: resistance or tolerance. In resistance, the body uses its resources to mount an all-out war against the invading threat and eliminate it.
When it comes to inflammation, not all organs are created equal. Some—including the brain and the spinal cord—are what’s known as “privileged.”By that, immunologists mean that it is very hard to produce inflammation in them, because these organs have very few immune cells. First, it is difficult for the immune cells to enter them to get in, and then the organs also have inhibitors that turn off the immune cells that do manage to gain entry.
Long considered one of the worst abdominal injuries, intestines damaged by trauma or illness are almost impossible to heal, and the injuries are fatal under certain circumstances. New technology may change that: 3D printing intestines from a subject’s own cells is fast approaching commercial..
TAM receptors tellimmune cells when it's time to switch from inflammation to tissue repair. More on this discovery fromYale’s Rothlin Ghosh Lab.
Rubor, calor, tumor, dolor: Dating from the early first century CE, these Latin words form an incantation that medical students recite to this day. They come from the Western world’s first known description of inflammation, authored by one Aulus Cornelius Celsus, a Roman who observed that the..
On one of the colder evenings of an unusually warm winter, dozens of faculty, faculty emeriti, and department chairs gathered in Yale School of Medicine (YSM)’s Medical Historical Library to shake hands with the new dean and raise their glasses to the former dean. The affair was comfortable and..
A devastating seizure disorder called new-onset refractory status epilepticus is better understood as Yale neurologists and affected families join forces.
In December 2019, Merck received FDA approval for the Ebola vaccine trademarked Ervebo. Merck had distributed this vaccine for free in the Democratic Republic of the Congo over the last year and a half.
Twice a month, the “Diagnosis” column appears in The New York Times Magazine. In 1,300 words, Lisa Sanders, MD ’97, HS ’00, associate professor of medicine at Yale School of Medicine (YSM), untangles a case that has had doctors scratching their heads as they sort through a patient’s symptoms for..
According to the lead author of a recent study, the keto diet’s effectiveness derives from its ability to trick the body into burning fat. Vishwa Deep Dixit, DVM, PhD, the Waldemar Von Zedwitz Professor of Comparative Medicine and professor of immunology, evaluated the mechanisms by which the..
Due to underlying disease, estimates of preventable deaths of hospitalized patients may be two to four times too high. The YSM and VA Connecticut study extrapolated likely numbers for the United States from results in European and Canadian hospitals.
A study co-authored by Yale sociologist Grace Kao, PhD, concludes that first grade teachers’ racial and gender biases about the abilities of their students affects how those students perform academically, as well as how those students view themselves and their abilities. Kao’s study was published..
A new alumni health group, co-founded by Christine Walsh, MD ’73, and Jamie Wells, MD, held its inaugural meeting at the Yale Club of NYC this winter. The Yale Alumni Health Network (YAHN) hopes to bring Yale alumni leaders together from all sectors that touch on health and health care: medical..
After COVID-19 struck, elderly patients at the VA Connecticut Healthcare System in West Haven were making difficult decisions about accessing care and trying to stay infection-free at the same time. A group of Yale undergraduates decided to do something about it.
Toward the end of January, face masks and other personal protective equipment (PPE) donated by people at Yale started leaving for Hunan, China. In the midst of its coronavirus outbreak, the country was in need.
Inflammation plays a key role in lupus. Research to unravel this complex aspect of the autoimmune disease is underway at the Yale School of Medicine.
Growing up in La Rioja, Spain—wine country—Judit Jimenez Sainz, PhD, was surrounded by people involved with the production of its famous red. Her grandfather made wine; both of her uncles own vineyards; and as a little girl, she picked grapes from the vines.
Chronic disability casts a shadow over the lives of people who live with it. One can never be sure when the condition or illness will flare up or be permanently exacerbated.
Just weeks into her tenure as the 19th dean of Yale School of Medicine, Nancy J. Brown, MD, found herself thrust into the center of a global pandemic.
For many years, this section was a space for readers’ feedback to a particular issue, or story. It is still that, and will continue to be so long as the U.
Our vocabulary for emotion is impoverished. We’re stressed or we’re good; we’re bummed or we’re okay.