Eugenia Chock, MD, MPH
Assistant Professor of Medicine (Rheumatology, Allergy & immunology)Cards
About
Research
Publications
2025
The relation between Down syndrome and co-occurring conditions in children and young adults: A population-based cohort in Denmark, 1977–2016
Yin C, Deng C, Crespi C, Bar S, Carey C, Brickner M, Chock E, Schafer E, Barjaktarevic I, Inoue K, Hansen J, Heck J. The relation between Down syndrome and co-occurring conditions in children and young adults: A population-based cohort in Denmark, 1977–2016. Research In Developmental Disabilities 2025, 167: 105167. PMID: 41274232, DOI: 10.1016/j.ridd.2025.105167.Peer-Reviewed Original ResearchConceptsCo-occurring conditionsPopulation-based retrospective cohort studyCommunity-based convenience sampleDanish national registersPopulation-based cohortDown syndromeYoung adultsYears of follow-upCerebral palsyPrevalence ratiosRetrospective cohort studyConvenience sampleCohort of childrenPrevalence differencesNational registersAbsolute riskSeptal defectHealthcare resourcesIncidence patternsAbsolute prevalenceCohort studyCongenital conditionSub-analysesPositive associationRisk of autoimmune diseasesExposure to nitrosatable drugs during pregnancy and childhood cancer: A cohort study in Taiwan
Deng C, Hu Y, Sirirungreung A, Chock E, Liew Z, Ritz B, Lee P, Heck J. Exposure to nitrosatable drugs during pregnancy and childhood cancer: A cohort study in Taiwan. International Journal Of Cancer 2025, 158: 2092-2101. PMID: 41203947, PMCID: PMC12683778, DOI: 10.1002/ijc.70240.Peer-Reviewed Original ResearchPopulation-based cohort studyChildhood cancer riskAssociated with higher riskCancer riskConfidence intervalsChildhood cancerCancer casesTaiwan Maternal and Child Health DatabaseChild Health DatabaseNitrosatable drug exposureNational Health Insurance programCox proportional hazards regression modelsRisk of neuroblastomaMother-child pairsProportional hazards regression modelsHealth Insurance ProgramDrug exposureHazards regression modelsCancer RegistryRisk of hepatoblastomaNitrosatable drugsWide confidence intervalsHealth databasesCohort studyHazard ratioApplying the small vulnerable newborns classification in the US context
Chock E, Rice T, Zhao T, Basile B, Rogne T. Applying the small vulnerable newborns classification in the US context. International Journal Of Gynecology & Obstetrics 2025, 172: 1261-1263. PMID: 40879134, PMCID: PMC12967255, DOI: 10.1002/ijgo.70479.Peer-Reviewed Original ResearchA Novel Prompt Engineering Framework of Large Language Models for Detecting Gout Flares
Qian L, Hu Q, Xie Q, Chock E, Xu H, Na H. A Novel Prompt Engineering Framework of Large Language Models for Detecting Gout Flares. 2025, 00: 343-351. DOI: 10.1109/ichi64645.2025.00047.Peer-Reviewed Original ResearchNatural language processingLanguage modelEngineering frameworkDomain-specific adaptationBERT modelDetection accuracyLanguage processingResource-scarce environmentsED visitsDatasetEmergency departmentAdequate continuity of careContinuity of careAdequate continuityGout flaresBERTTraditional modelsFrameworkPerformanceGout careDetection guidelinesABS0383 PREGNANCY OUTCOMES IN PATIENTS EXPOSED TO VOCLOSPORIN: A SUMMARY OF AVAILABLE DATA FROM CLINICAL TRIALS AND POST-MARKETING SOURCES
Chock E, Begum T, Dao K, Zhou C, Dardeno M. ABS0383 PREGNANCY OUTCOMES IN PATIENTS EXPOSED TO VOCLOSPORIN: A SUMMARY OF AVAILABLE DATA FROM CLINICAL TRIALS AND POST-MARKETING SOURCES. Annals Of The Rheumatic Diseases 2025, 84: 2199-2200. DOI: 10.1016/j.ard.2025.06.1840.Peer-Reviewed Original ResearchFemale patients of child-bearing ageReports of pregnancyClinical development programPatients of child-bearing ageSystemic lupus erythematosusFetal outcomesPost-marketing reportsActive LNPregnancy outcomesLupus nephritisFemale patientsChild-bearing ageClinical trialsLive birthsPregnant patientsMycophenolate mofetilPregnant womenElective abortionAdequate contraceptive precautionsIntrauterine growth retardationActive lupus nephritisHistory of LNPoor pregnancy outcomesDrug-associated risksPeriod of organogenesis
2024
Fetal Growth Associated with Maternal Rheumatoid Arthritis and Juvenile Idiopathic Arthritis
Chock E, Glintborg B, Liew Z, Pedersen L, Thunbo M. Fetal Growth Associated with Maternal Rheumatoid Arthritis and Juvenile Idiopathic Arthritis. Healthcare 2024, 12: 2390. PMID: 39685012, PMCID: PMC11641325, DOI: 10.3390/healthcare12232390.Peer-Reviewed Original ResearchJuvenile idiopathic arthritisEstimated Fetal WeightRheumatoid arthritisGestational ageIdiopathic arthritisMaternal RAWeeks of gestational ageFetal growth indicatorsFetal Medicine DatabasePregnancies of patientsEvaluate fetal growthInternational Classification of Diseases-10 codesAssociated with SGAFetal biometric measurementsAdverse pregnancy outcomesLow birth weightPopulation-based cohort studyFetal ultrasound scanOffspring of patientsNational Patient RegistrySingleton pregnanciesPregnant patientsZ-score differenceFetal weightPreterm birth
2023
Proteomic Profiling of Different Antiphospholipid Antibody-Positive Phenotypes: Results from Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Registry
Pine A, Butt A, Garcia-Milian R, Gu S, Restrepo V, Chock Y, Hwa J, Tormey C, Rinder H, Goshua G, Belmont H, Bertolaccini M, Branch D, Erhan D, Kello N, Knight J, Petri M, Willis R, Lee A, Sharda A. Proteomic Profiling of Different Antiphospholipid Antibody-Positive Phenotypes: Results from Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Registry. Blood 2023, 142: 2575. DOI: 10.1182/blood-2023-185232.Peer-Reviewed Original ResearchNeutrophil extracellular trapsAntiphospholipid syndromeHumoral immune responseImmune responseClinical phenotypePathophysiology of APSPathogenesis of APSSapporo classification criteriaAPL-positive patientsPathway enrichment analysisEffector cell differentiationAntiPhospholipid Syndrome AllianceDifferent clinical phenotypesProteomic profilingPlasma proteomic profilingPatient plasma samplesAPL antibodiesAPS pathogenesisAntiphospholipid antibodiesObstetric complicationsPositive aPLCytokine stormMedian ageMicrovascular disordersConcurrent diagnosisPatient perspectives on telemedicine use in rheumatology during the COVID-19 pandemic: survey results from the COVID-19 Global Rheumatology Alliance
Maheswaranathan M, Miller B, Ung N, Sinha R, Harrison C, Egeli B, Degirmenci H, Sirotich E, Liew J, Grainger R, Chock E. Patient perspectives on telemedicine use in rheumatology during the COVID-19 pandemic: survey results from the COVID-19 Global Rheumatology Alliance. Clinical Rheumatology 2023, 43: 543-552. PMID: 37552351, DOI: 10.1007/s10067-023-06717-2.Peer-Reviewed Original ResearchConceptsRheumatic diseasesPerson visitsTelemedicine useMedication changesCOVID-19 pandemicCare of patientsPerspectives of patientsMethodsAn anonymous online surveyPerspectives of telemedicineDisease activityComplete responseMost patientsPatient's perspectiveTelemedicine effectivenessPatientsAnonymous online surveyFree-text responsesSimilar effectivenessDiseaseVisitsTelemedicine usersRheumatologyYounger participantsTelemedicineClinical tasksEfforts to Better Characterize "Antiphospholipid Antibody Nephropathy" for the 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria: Renal Pathology Subcommittee Report.
Barbhaiya M, Taghavi M, Zuily S, Domingues V, Chock E, Tektonidou M, Erkan D, Seshan S. Efforts to Better Characterize "Antiphospholipid Antibody Nephropathy" for the 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria: Renal Pathology Subcommittee Report. The Journal Of Rheumatology 2023, 51: 150-159. PMID: 37399462, DOI: 10.3899/jrheum.2022-1200.Peer-Reviewed Original ResearchConceptsAntiphospholipid syndromeRenal Pathology SocietyAntiphospholipid syndrome classification criteriaAmerican College of Rheumatology/European Alliance of AssociationsAmerican CollegeDelphi surveyClassification criteriaRenal biopsy reportsAssociation of nephropathyChronic pathological lesionsInternational patient registriesAntiphospholipid antibodiesBiopsy reportsHistopathological diagnosisRenal biopsyHistopathologic terminologyPathological featuresPatient RegistryDiagnostic criteriaLiterature reviewNephropathySurvey respondentsAntiphospholipidPathology SocietyPathological lesionsOffspring neurodevelopmental outcomes born to parents with chronic inflammatory arthritis using antirheumatic therapies: A scoping review
Chock E, Dahal S, Grimshaw A, Suter L, Liew Z, Felson D. Offspring neurodevelopmental outcomes born to parents with chronic inflammatory arthritis using antirheumatic therapies: A scoping review. Seminars In Arthritis And Rheumatism 2023, 61: 152230. PMID: 37295300, PMCID: PMC10521166, DOI: 10.1016/j.semarthrit.2023.152230.Peer-Reviewed Original ResearchConceptsChronic inflammatory arthritisOffspring neurodevelopmental outcomesAntirheumatic therapyNeurodevelopmental outcomesInflammatory arthritisTumor necrosis factor-alpha inhibitorsNecrosis factor-alpha inhibitorsNonsteroidal anti-inflammatory drugsEarly first trimesterOffspring health outcomesAnti-inflammatory drugsMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsWeb of ScienceAttention deficit hyperactive disorderCorticosteroid useRheumatic diseasesFirst trimesterCochrane LibraryAlpha inhibitorsStudy qualityMedication safetyFetal wellbeingIndependent reviewersMost women
Academic Achievements & Community Involvement
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Overview
Eugenia Chock, MD, MPH, is a physician and clinical researcher investigating maternal-child health among patients with rheumatic diseases. She has strong interests in reproductive rheumatology and utilizing large datasets to support her research. Dr. Chock passionately cares for patients with rheumatic diseases with reproductive health needs in a collaborative model with reproductive health specialists.
Clinical Specialties
Rheumatology
Fact Sheets
Lupus
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Yale Medicine News
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- March 31, 2026
Four In Five: Women Carry the Burden of Autoimmune Disorders in America
- May 27, 2025Source: Yale News
Yale Planetary Solutions Announces a New ‘Constellation’ of Grants
- September 10, 2024
Using AI to Detect Autoimmune Diseases in Women
- January 23, 2024
Investigating Maternal Inflammatory Arthritis and Pregnancy Outcomes
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