Voluntary Faculty
Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsMary Lou (Maria Lucia) Gaeta, MD, JD
Assistant Clinical ProfessorDownloadHi-Res Photo
About
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Appointments
Pediatric Critical Care Medicine
Assistant Clinical ProfessorPrimary
Other Departments & Organizations
- Pediatric Critical Care Medicine
- Pediatric Hospitalist Program
- Pediatric Intensive Care Unit
- Program for Biomedical Ethics
- Yale Medicine
Education & Training
- JD
- University of Connecticut School of Law (2015)
- MD
- University of Torino (1993)
Research
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Mary Lou (Maria Lucia) Gaeta's published research.
Publications Timeline
A big-picture view of Mary Lou (Maria Lucia) Gaeta's research output by year.
Jordan Pober, MD, PhD
7Publications
250Citations
Publications
2004
Octreotide and low-fat breast milk in postoperative chylothorax
Hamdan M, Gaeta M. Octreotide and low-fat breast milk in postoperative chylothorax. The Annals Of Thoracic Surgery 2004, 77: 2215-2217. PMID: 15172311, DOI: 10.1016/s0003-4975(03)01464-4.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
2003
Histamine Antagonizes Tumor Necrosis Factor (TNF) Signaling by Stimulating TNF Receptor Shedding from the Cell Surface and Golgi Storage Pool*
Wang J, Al-Lamki RS, Zhang H, Kirkiles-Smith N, Gaeta ML, Thiru S, Pober JS, Bradley JR. Histamine Antagonizes Tumor Necrosis Factor (TNF) Signaling by Stimulating TNF Receptor Shedding from the Cell Surface and Golgi Storage Pool*. Journal Of Biological Chemistry 2003, 278: 21751-21760. PMID: 12646554, DOI: 10.1074/jbc.m212662200.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsADAM ProteinsADAM17 ProteinAnimalsBrefeldin ACell MembraneCell SeparationCells, CulturedDose-Response Relationship, DrugEndothelium, VascularEnzyme InhibitorsEnzyme-Linked Immunosorbent AssayFlow CytometryGolgi ApparatusHistamineHumansI-kappa B ProteinsImmunoblottingImmunohistochemistryMetalloendopeptidasesMiceMicroscopy, ConfocalMicroscopy, ElectronMicroscopy, FluorescenceMitogen-Activated Protein Kinase 3Mitogen-Activated Protein KinasesNF-KappaB Inhibitor alphaNitric Oxide SynthaseRecombinant Fusion ProteinsReverse Transcriptase Polymerase Chain ReactionSignal TransductionSkinTime FactorsTumor Necrosis Factor-alphaConceptsTumor necrosis factorEndothelial cellsNecrosis factorNovel anti-inflammatory activityPro-inflammatory functionsAnti-inflammatory activityTNF-alpha-converting enzymeEndothelial adhesion moleculesCultured human endothelial cellsTNF-alpha protease inhibitorVascular endothelial cellsCultured endothelial cellsHuman endothelial cellsHistamine injectionH1 receptorsReceptor lossCell surfaceImmunodeficient miceMitogen-activated protein kinase pathwaySurface TNFR1TNF receptorShed receptorCell surface receptorsTNF actionTransient loss
2000
Caveolin-1 Associates with TRAF2 to Form a Complex That Is Recruited to Tumor Necrosis Factor Receptors*
Feng X, Gaeta M, Madge L, Yang J, Bradley J, Pober J. Caveolin-1 Associates with TRAF2 to Form a Complex That Is Recruited to Tumor Necrosis Factor Receptors*. Journal Of Biological Chemistry 2000, 276: 8341-8349. PMID: 11112773, DOI: 10.1074/jbc.m007116200.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCaveolin-1Confocal fluorescence microscopyIntracellular regionNecrosis factor receptor-associated factor 2TNF receptor 2Receptor-associated factor 2TNF receptor 1Promoter-reporter geneCaveolin-1 associatesFluorescence microscopyProtein caveolin-1Caveolin-1 proteinHuman embryonic kidney 293 cellsIntracellular adapter proteinEmbryonic kidney 293 cellsAbsence of ligandRegions of enrichmentKidney 293 cellsEndogenous TRAF2HEK-293 cellsAdapter proteinCultured human umbilical vein endothelial cellsHuman umbilical vein endothelial cellsPlasma membraneUmbilical vein endothelial cellsThe Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention of the Receptor and Mediates Receptor Desensitization
Gaeta M, Johnson D, Kluger M, Pober J. The Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention of the Receptor and Mediates Receptor Desensitization. Laboratory Investigation 2000, 80: 1185-1194. PMID: 10950109, DOI: 10.1038/labinvest.3780126.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsDeath domainGolgi retentionPlasma membraneC-terminal death domainGolgi apparatusNF-kappaBDominant negative inhibitorWild-type receptorDisparate localizationTNF responseIntracellular domainC-terminusEndothelial cellsNegative inhibitorTNF signalsWild typeTumor necrosis factor receptor 1Chimeric receptorsFactor receptor 1Necrosis factor receptor 1Endogenous receptorsBasal expressionReceptor moleculesType receptorTNF action
1999
The Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention in Endothelial Cells
Gaeta M, Johnson D, Pober J. The Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention in Endothelial Cells. Pediatric Research 1999, 45: 39-39. DOI: 10.1203/00006450-199904020-00238.Peer-Reviewed Original ResearchCitations
1998
Treatment of traumatic brain injury with hypothermia
Biagas K, Gaeta M. Treatment of traumatic brain injury with hypothermia. Current Opinion In Pediatrics 1998, 10: 271-277. PMID: 9716889, DOI: 10.1097/00008480-199806000-00009.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsTraumatic brain injuryBrain injuryAttenuation of injuryEffects of hypothermiaNew effective therapiesSystemic hypothermiaHypothermic therapyClinical trialsEffective therapySuch injuriesLaboratory evidenceHypothermiaInjuryMild formNitric oxideTherapyPutative mechanismsPatientsMolecular mechanismsSustained applicationTreatmentFree radicalsChildrenComplicationsInflammationLocalization of Epitope-tagged Tumor Necrosis Factor Receptors 1 and 2 in Transfected Endothelial Cells • 196
Gaeta M, Johnson D, Kluger M, Pober J. Localization of Epitope-tagged Tumor Necrosis Factor Receptors 1 and 2 in Transfected Endothelial Cells • 196. Pediatric Research 1998, 43: 36-36. DOI: 10.1203/00006450-199804001-00217.Peer-Reviewed Original Research
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