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Titles
Chief Resident
Departments & Organizations
Education & Training
- PhD
- Washington University School of Medicine, Neuroscience (2022)
- MD
- Washington University School of Medicine, Neuroscience (2022)
- BS
- University of Puerto Rico - Rio Piedras, Molecular and Cell Biology (2012)
Research
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Overview
Medical Research Interests
Neurobiology; Neurosciences; Pain
Research at a Glance
Publications Timeline
A big-picture view of Jose G Grajales's research output by year.
17Publications
Publications
2023
Cell type-specific dissection of sensory pathways involved in descending modulation.
Nguyen E, Grajales-Reyes JG, Gereau RW 4th, Ross SE. Cell type-specific dissection of sensory pathways involved in descending modulation. Trends Neurosci 2023, 46: 539-550. PMID: 37164868, DOI: 10.1016/j.tins.2023.04.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2021
Wireless multilateral devices for optogenetic studies of individual and social behaviors.
Yang Y, Wu M, Vázquez-Guardado A, Wegener AJ, Grajales-Reyes JG, Deng Y, Wang T, Avila R, Moreno JA, Minkowicz S, Dumrongprechachan V, Lee J, Zhang S, Legaria AA, Ma Y, Mehta S, Franklin D, Hartman L, Bai W, Han M, Zhao H, Lu W, Yu Y, Sheng X, Banks A, Yu X, Donaldson ZR, Gereau RW, Good CH, Xie Z, Huang Y, Kozorovitskiy Y, Rogers JA. Wireless multilateral devices for optogenetic studies of individual and social behaviors. Nature Neuroscience 2021, 24: 1035-1045. PMID: 33972800, PMCID: PMC8694284, DOI: 10.1038/s41593-021-00849-x.Peer-Reviewed Original ResearchSurgical implantation of wireless, battery-free optoelectronic epidural implants for optogenetic manipulation of spinal cord circuits in mice.
Grajales-Reyes JG, Copits BA, Lie F, Yu Y, Avila R, Vogt SK, Huang Y, Banks AR, Rogers JA, Gereau RW, Golden JP. Surgical implantation of wireless, battery-free optoelectronic epidural implants for optogenetic manipulation of spinal cord circuits in mice. Nature Protocols 2021, 16: 3072-3088. PMID: 34031611, PMCID: PMC9273129, DOI: 10.1038/s41596-021-00532-2.Peer-Reviewed Original ResearchCellular, circuit and transcriptional framework for modulation of itch in the central amygdala.
Samineni VK, Grajales-Reyes JG, Grajales-Reyes GE, Tycksen E, Copits BA, Pedersen C, Ankudey ES, Sackey JN, Sewell SB, Bruchas MR, Gereau RW. Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala. ELife 2021, 10 PMID: 34032210, PMCID: PMC8172243, DOI: 10.7554/eLife.68130.Peer-Reviewed Original Research
2020
A Potential Role for Stress-Induced Microbial Alterations in IgA-Associated Irritable Bowel Syndrome with Diarrhea.
Rengarajan S, Knoop KA, Rengarajan A, Chai JN, Grajales-Reyes JG, Samineni VK, Russler-Germain EV, Ranganathan P, Fasano A, Sayuk GS, Gereau RW, Kau AL, Knights D, Kashyap PC, Ciorba MA, Newberry RD, Hsieh CS. A Potential Role for Stress-Induced Microbial Alterations in IgA-Associated Irritable Bowel Syndrome with Diarrhea. Cell Reports Medicine 2020, 1 PMID: 33196055, PMCID: PMC7659537, DOI: 10.1016/j.xcrm.2020.100124.Peer-Reviewed Original Research
2019
Cell type-specific modulation of sensory and affective components of itch in the periaqueductal gray.
Samineni VK, Grajales-Reyes JG, Sundaram SS, Yoo JJ, Gereau RW. Cell type-specific modulation of sensory and affective components of itch in the periaqueductal gray. Nature Communications 2019, 10: 4356. PMID: 31554789, PMCID: PMC6761157, DOI: 10.1038/s41467-019-12316-0.Peer-Reviewed Original ResearchBattery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves.
Zhang Y, Mickle AD, Gutruf P, McIlvried LA, Guo H, Wu Y, Golden JP, Xue Y, Grajales-Reyes JG, Wang X, Krishnan S, Xie Y, Peng D, Su CJ, Zhang F, Reeder JT, Vogt SK, Huang Y, Rogers JA, Gereau RW. Battery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves. Science Advances 2019, 5: eaaw5296. PMID: 31281895, PMCID: PMC6611690, DOI: 10.1126/sciadv.aaw5296.Peer-Reviewed Original ResearchUntangling a canopy of spinal itch circuits.
Grajales-Reyes JG, Samineni VK. Untangling a canopy of spinal itch circuits. Pain 2019, 160: 987-988. PMID: 30817439, PMCID: PMC7386460, DOI: 10.1097/j.pain.0000000000001537.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2018
The alpha7-nicotinic receptor contributes to gp120-induced neurotoxicity: implications in HIV-associated neurocognitive disorders.
Capó-Vélez CM, Morales-Vargas B, García-González A, Grajales-Reyes JG, Delgado-Vélez M, Madera B, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. The alpha7-nicotinic receptor contributes to gp120-induced neurotoxicity: implications in HIV-associated neurocognitive disorders. Scientific Reports 2018, 8: 1829. PMID: 29379089, PMCID: PMC5788855, DOI: 10.1038/s41598-018-20271-x.Peer-Reviewed Original ResearchMiniaturized, Battery-Free Optofluidic Systems with Potential for Wireless Pharmacology and Optogenetics.
Noh KN, Park SI, Qazi R, Zou Z, Mickle AD, Grajales-Reyes JG, Jang KI, Gereau RW, Xiao J, Rogers JA, Jeong JW. Miniaturized, Battery-Free Optofluidic Systems with Potential for Wireless Pharmacology and Optogenetics. Small (Weinheim An Der Bergstrasse, Germany) 2018, 14 PMID: 29215787, PMCID: PMC5912318, DOI: 10.1002/smll.201702479.Peer-Reviewed Original Research
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May 202622Friday
Everyone Jose G Grajales, MD, PhD - Tilman Chambers