Jim Ho, MD
Clinical FellowCards
About
Research
Publications
2025
Challenges and strategies in the care of older adults across the continuum of intensive and post-intensive care medicine
Ferrante L, Vallet H, Ho J, Brummel N. Challenges and strategies in the care of older adults across the continuum of intensive and post-intensive care medicine. Intensive Care Medicine 2025, 52: 63-75. PMID: 41428207, DOI: 10.1007/s00134-025-08253-w.Peer-Reviewed Original ResearchReply to: Reevaluating Functional Recovery Post‐COVID‐19: A Call for Broader Considerations
Ho J, McAvay G, Murphy T, Acampora D, Araujo K, Geda M, Gill T, Hajduk A, Cohen A, Ferrante L. Reply to: Reevaluating Functional Recovery Post‐COVID‐19: A Call for Broader Considerations. Journal Of The American Geriatrics Society 2025, 73: 3281-3282. PMID: 40390544, PMCID: PMC12353894, DOI: 10.1111/jgs.19534.Peer-Reviewed Original ResearchFunctional Trajectories After COVID‐19 Hospitalization Among Older Adults
Ho J, McAvay G, Murphy T, Acampora D, Araujo K, Geda M, Gill T, Hajduk A, Cohen A, Ferrante L. Functional Trajectories After COVID‐19 Hospitalization Among Older Adults. Journal Of The American Geriatrics Society 2025, 73: 1733-1741. PMID: 40096163, PMCID: PMC12213203, DOI: 10.1111/jgs.19420.Peer-Reviewed Original ResearchConceptsIn-hospital deliriumFunction trajectoriesFactors associated with trajectory membershipTrajectory membershipAssociation of potential risk factorsCommunity-dwelling adultsRisk factorsModifiable risk factorsMedical decision-makingOlder survivorsPotential risk factorsOlder adultsSeverity of illnessAssociated with membershipYears of ageCOVID-19 hospitalizationModerate trajectoryLatent class analysisMultinomial regressionSurvive hospitalizationCOVID-19DisabilitySeverity trajectoriesHospitalClass analysisChapter 1 What is immunoengineering?
Bakhshi P, Webster T, Ho J, Zaer N, Zanganeh S. Chapter 1 What is immunoengineering? 2025, 1-20. DOI: 10.1016/b978-0-443-21521-6.00001-6.Peer-Reviewed Original ResearchChapter 11 Cytokine engineering for targeted immunotherapy
Bakhshi P, Ho J, Zaer N, Webster T, Zanganeh S. Chapter 11 Cytokine engineering for targeted immunotherapy. 2025, 335-370. DOI: 10.1016/b978-0-443-21521-6.00011-9.Peer-Reviewed Original ResearchChapter 10 Chemistry of immunoengineering biomaterials
Bakhshi P, Ho J, Zaer N, Webster T, Zanganeh S. Chapter 10 Chemistry of immunoengineering biomaterials. 2025, 313-334. DOI: 10.1016/b978-0-443-21521-6.00010-7.Peer-Reviewed Original ResearchBiomaterial chemistryCreation of scaffoldsCombination of biomaterialsHydrogel fabricationScaffold designTissue engineeringFabrication techniquesFunction engineeringZwitterionic materialsChemistry of biomaterialsNative tissueNanoscale modificationSurface chemistryDrug delivery platformTissue regenerationPatient-specific implantsFabricationBiomaterialsSurface chargeHost immune systemImmune response modulationMaterials scienceEngineeringMaterialsSurface
2024
Peak expiratory flow predicts motoric cognitive risk syndrome: A cohort study
Ho J, Kuschner W, Verghese J. Peak expiratory flow predicts motoric cognitive risk syndrome: A cohort study. Journal Of The American Geriatrics Society 2024, 73: 887-893. PMID: 39382106, PMCID: PMC11908954, DOI: 10.1111/jgs.19210.Peer-Reviewed Original ResearchConceptsMotoric cognitive risk syndromeIncident MCRNational Health and Aging Trends StudyLow peak expiratory flowAssociated with higher prevalencePeak expiratory flowIncidence of MCRPrevalence of motoric cognitive risk syndromeRisk syndromePercentile groupHealth-related covariatesDiscrete-time proportional hazards modelsRisk factorsModifiable risk factorsCohort of adultsSubjective cognitive complaintsPoor respiratory functionYears of follow-upSlow gaitPredementia syndromesProportional hazards modelTrends StudyLongitudinal associationsYears of ageCognitive complaintsSex-specific outcomes in cancer therapy: the central role of hormones
Bakhshi P, Ho J, Zanganeh S. Sex-specific outcomes in cancer therapy: the central role of hormones. Frontiers In Medical Technology 2024, 6: 1320690. PMID: 38362126, PMCID: PMC10867131, DOI: 10.3389/fmedt.2024.1320690.Peer-Reviewed Original ResearchHormone replacement therapyHormone-sensitive cancersSex hormonesTreatment outcomesCancer therapyCancer progressionEstrogen receptor-negativeEstrogen receptor-positiveAndrogen receptor signalingSex-specific outcomesInhibit cancer progressionReceptor-negativeReceptor-positiveAromatase inhibitorsReplacement therapyTreatment responseAnti-androgenHormone levelsTherapeutic outcomesPersonalized therapyHormonal profileReceptor signalingTherapyCancer treatmentCancer
2023
PEAK EXPIRATORY FLOW AND MOTORIC COGNITIVE RISK SYNDROME
HO J, VERGHESE J. PEAK EXPIRATORY FLOW AND MOTORIC COGNITIVE RISK SYNDROME. Chest 2023, 164: a5817. DOI: 10.1016/j.chest.2023.07.3750.Peer-Reviewed Original ResearchFerroptosis: Environmental causes, biological redox signaling responses, cancer and other health consequences
Sepand M, Bigdelou B, Maghsoudi A, Sanadgol N, Ho J, Chauhan P, Raoufi M, Kermanian A, Esfandyarpour R, Hajipour M, Zanganeh S. Ferroptosis: Environmental causes, biological redox signaling responses, cancer and other health consequences. Coordination Chemistry Reviews 2023, 480: 215024. DOI: 10.1016/j.ccr.2023.215024.Peer-Reviewed Original ResearchReactive oxygen speciesCell deathPyridine nucleotide redox systemsRegulation of cell fateReactive oxygen species signalingIron-mediated cell deathTrigger cell deathCellular redox signalingCell fateEffects of environmental chemical exposureProtein activityRedox messengersRedox signalingCell metabolismHuman diseasesROS amountsImpact of ferroptosisIntracellular levelsChemical stressorsExposure to xenobioticsOxygen speciesRedox statusFerroptosisNormal metabolismCell status
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