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TZID:America/New_York
X-LIC-LOCATION:America/New_York
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DTSTART:20241103T020000
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TZNAME:EST
TZOFFSETFROM:-0400
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DESCRIPTION:Abstract: This talk presents our approach to virtual cell mode
 ling by building computational representations of core cellular processes
 —transcription\, translation\, and cell state dynamics—using specialized 
 models: Epinet for transcription\, NVCell for single-cell multiomic state
  modeling\, and CodonFM for translation. In this talk\, we focus on Codon
 FM and introduce a suite of codon-resolution language models trained on o
 ver 120 million coding sequences from 22\,000 species. Unlike traditional
  protein models that ignore synonymous codon variation\, cdsFM captures t
 he functional and regulatory impact of codon choice\, learning the struct
 ure of the genetic code and offering new insights into how coding sequenc
 es shape protein expression in the cell.\n\nSpeaker:\nLaksshman Sundaram\
 n\nAdmission:\nFree\n\nFood:\nYou must register to receive a boxed lunch 
 at the event.\nA registration sheet will be utilized at the event.\n\nDet
 ails URL:\nhttps://medicine.yale.edu/event/laksshman-sundaram-gives-speci
 al-ycccsei-seminar/\n
DTEND;TZID=America/New_York:20250807T131500
DTSTAMP:20260514T221113Z
DTSTART;TZID=America/New_York:20250807T120000
GEO:41.304215;-72.931754
LOCATION:1116\, 100 College Street\, New Haven\, CT\, United States
SEQUENCE:0
STATUS:Confirmed
SUMMARY:AT CAPACITY - Laksshman Sundaram gives Special YCC/CSEI Seminar- R
 EGISTRATION CLOSED
UID:079de71e-b159-4fab-bbac-dbcb011e769d
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