https://websites4-live-prod.ysmdevs.com/pharm/news-rss/?orgId=108864&title=Latest+News+from+the+Department+of+Pharmacology A selection of the latest research, academic, and other newsworthy developments at Pharmacology en-us Copyright 2026 Yale School of Medicine Mon, 18 May 2026 01:21:32 Z https://news.yale.edu/2026/05/07/yale-led-technology-receives-fda-approval-breast-cancer-treatment https://news.yale.edu/2026/05/07/yale-led-technology-receives-fda-approval-breast-cancer-treatment The biotech company Arvinas was originally founded based on pioneering research from Yale chemist Craig Crews into PROTAC protein degraders. Thu, 07 May 2026 04:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/perspectives-of-women-in-science-lectureship-on-may-19/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/perspectives-of-women-in-science-lectureship-on-may-19/ Please join us on Tuesday, May 19, at 4 pm., in the Mary S. Harkness Auditorium for the eighth annual Perspectives of Women in Science Lectureship hosted by the MD-PhD Program and the Office of the Dean of YSM. Thu, 16 Apr 2026 04:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/oncology/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/oncology/ Yale Cancer Center Experts to Present Latest Findings Mon, 06 Apr 2026 12:30:00 Z https://ctcase.org/connecticut-academy-science-engineering-elects-36-new-members-2026/ https://ctcase.org/connecticut-academy-science-engineering-elects-36-new-members-2026/ The Connecticut Academy of Science and Engineering (CASE), announces the election of thirty-six of Connecticut’s leading experts in science, technology, engineering, mathematics, and medicine to membership in the Academy. The new members will be introduced at the Academy’s 51st Annual Dinner to be held at the Aqua Turf Club in Plantsville on May 19, 2026. Thu, 26 Mar 2026 16:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/connecticut-academy-of-science-and-engineering-elects-eight-from-ysm/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/connecticut-academy-of-science-and-engineering-elects-eight-from-ysm/ Eight Yale School of Medicine faculty members are among the leading experts in science, technology, engineering, mathematics, and medicine newly elected to the Connecticut Academy of Science and Engineering. Fri, 13 Mar 2026 14:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/how-lungs-age-and-targets-for-preventing-disease/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/how-lungs-age-and-targets-for-preventing-disease/ Scientists created a cellular atlas of the lungs to pinpoint cells especially vulnerable to aging. They could be targets for preventing acute and chronic lung diseases. Tue, 03 Mar 2026 16:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/standout-research-clinical-care-and-staff-support-recognized/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/standout-research-clinical-care-and-staff-support-recognized/ A dozen awards honored 15 people at January's Yale Cancer Center Annual Awards for work in 2025. Wed, 28 Jan 2026 05:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/genetic-study-of-rare-endometrial-cancer-uncovers-potential-treatments/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/genetic-study-of-rare-endometrial-cancer-uncovers-potential-treatments/ Researchers uncovered potential treatment strategies for stromal sarcoma of the uterus by establishing a more detailed understanding of the aggressive tumors at the molecular level. Mon, 26 Jan 2026 20:00:00 Z https://www.nejm.org/doi/full/10.1056/NEJMe2514042 https://www.nejm.org/doi/full/10.1056/NEJMe2514042 Combination chemotherapy has long been a mainstay of cancer treatment, although early mechanism-based therapies showed little promise. More than 50 years later, this foundational principle — in which biologic rationale is used to guide the choice of treatment combinations — is being applied to the leading cause of cancer-related deaths: lung cancer. Today, genomic profiling, targeted agents, and strategies informed by resistance mechanisms are reshaping care for epithelial growth factor receptor (EGFR)–mutated non–small-cell lung cancer (NSCLC). Mon, 05 Jan 2026 05:00:00 Z https://news.yale.edu/2025/12/01/pioneering-drug-development-one-company-time https://news.yale.edu/2025/12/01/pioneering-drug-development-one-company-time In a Q&A, trailblazing chemist Craig Crews discusses the transformative science emerging from Yale—and why translating innovative ideas into real-world businesses is good for the university and New Haven. Mon, 01 Dec 2025 21:00:00 Z https://medicine.yale.edu/ysm/news/yale-medicine-magazine/article/sodium-channel-blockers/ https://medicine.yale.edu/ysm/news/yale-medicine-magazine/article/sodium-channel-blockers/ A new type of pain medication is here, delivering treatment without the side effects and potential for addiction that come with opioids. Mon, 01 Dec 2025 05:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/how-cancer-cells-tolerate-missing-chromosomes/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/how-cancer-cells-tolerate-missing-chromosomes/ Cancer cells often exhibit aneuploidy, or an abnormal number of chromosomes. Researchers uncovered a new mechanism that challenges predominant beliefs about how cells compensate for chromosomal imbalances. Wed, 26 Nov 2025 16:00:00 Z https://news.yale.edu/2025/11/13/soaking-anti-cancer-properties-south-korean-sea-sponge https://news.yale.edu/2025/11/13/soaking-anti-cancer-properties-south-korean-sea-sponge Yale researchers have completed a challenging synthesis of a molecule that may have potent anti-cancer effects. Fri, 14 Nov 2025 05:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/ysm-faculty-recognized-with-yale-faculty-innovation-awards/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/ysm-faculty-recognized-with-yale-faculty-innovation-awards/ Eight YSM faculty innovators received 2025 Yale Faculty Innovation Awards for translating breakthrough research into ventures that address some of the world’s most pressing challenges. Wed, 12 Nov 2025 20:00:00 Z https://ventures.yale.edu/news/lab-launch-eleven-faculty-innovators-recognized-turning-research-real-world-impact https://ventures.yale.edu/news/lab-launch-eleven-faculty-innovators-recognized-turning-research-real-world-impact The 2025 Yale Faculty Innovation Awards honor academic founders whose startups—rooted in Yale research—are advancing breakthroughs in health, sustainability, and engineering. Wed, 12 Nov 2025 16:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/unlocking-skins-natural-healing-power/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/unlocking-skins-natural-healing-power/ Researchers show that embryonic skin stem cells rely on a specialized mechanism to resist injury. The findings could lead to new strategies for repairing wounds and regenerating damaged tissues. Fri, 10 Oct 2025 09:00:00 Z https://www.hcplive.com/view/uncovering-drivers-possible-treatment-noonan-syndrome-heart-defects https://www.hcplive.com/view/uncovering-drivers-possible-treatment-noonan-syndrome-heart-defects Noonan syndrome with multiple lentigines (NSML) is a rare genetic disorder that causes short stature, distinctive facial features, and clusters of dark skin spots called lentigines. But its most serious impact is a dangerous thickening of the heart muscle, the onset of which is not well understood. Fri, 03 Oct 2025 04:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/yales-lung-cancer-spore-grant-renewed-by-national-cancer-institute/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/yales-lung-cancer-spore-grant-renewed-by-national-cancer-institute/ Yale Cancer Center's Specialized Program of Research Excellence (SPORE) in Lung Cancer has been awarded a renewal grant from the National Cancer Institute (NCI) for year 11 of the program. The prestigious grant, totaling $12M over five years, will provide critical funding to advance groundbreaking lung cancer research and accelerate progress in the prevention, detection, and treatment of this disease. Thu, 18 Sep 2025 04:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/uncovering-drivers-ofand-treatment-fornoonan-syndrome-heart-defects/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/uncovering-drivers-ofand-treatment-fornoonan-syndrome-heart-defects/ Yale researchers identified the molecular drivers of a heart condition tied to Noonan syndrome—and they may have found a treatment. Mon, 15 Sep 2025 16:00:00 Z https://ventures.yale.edu/news/yales-colton-center-autoimmunity-announces-2025-awardees-advancing-innovation-autoimmune https://ventures.yale.edu/news/yales-colton-center-autoimmunity-announces-2025-awardees-advancing-innovation-autoimmune The Colton Center for Autoimmunity at Yale University announces the recipients of its 2025 awards, recognizing outstanding, translationally focused research projects that aim to accelerate novel diagnostics, therapeutics, vaccines and technological innovations in autoimmunity. Wed, 16 Jul 2025 12:00:00 Z https://ventures.yale.edu/news/eight-translational-biotech-projects-selected-2025-blavatnik-accelerator-awards https://ventures.yale.edu/news/eight-translational-biotech-projects-selected-2025-blavatnik-accelerator-awards The mid-cycle Blavatnik Accelerator Awards recognize eight Yale early-stage innovations tackling cancer, rare disease, and neurodegeneration through digital platforms, RNA therapies, and next-gen molecules. Tue, 08 Jul 2025 12:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/dr-stefania-nicoli-elected-fellow-of-the-american-heart-association/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/dr-stefania-nicoli-elected-fellow-of-the-american-heart-association/ Dr. Stefania Nicoli, PhD, Associate Professor at Yale School of Medicine was elected as a Fellow of the American Heart Association (FAHA), an honor that recognizes her outstanding scientific achievements and her continued commitment to advancing cardiovascular research. Mon, 07 Jul 2025 04:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/ai-helps-researchers-understand-lung-disease-and-proposes-treatment/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/ai-helps-researchers-understand-lung-disease-and-proposes-treatment/ Yale researchers developed an AI model that illuminates critical details about—and possible treatments for—idiopathic pulmonary fibrosis. It could do so for many other diseases. Fri, 20 Jun 2025 09:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/advancing-neuroscience-research-with-high-speed-automated-electrophysiology/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/advancing-neuroscience-research-with-high-speed-automated-electrophysiology/ In a major advancement, Yale researchers have unveiled a high-throughput automated method that captures the electrical activity of large numbers of neurons simultaneously. Fri, 13 Jun 2025 14:00:00 Z https://news.yale.edu/2025/05/01/five-yale-professors-elected-national-academy-sciences https://news.yale.edu/2025/05/01/five-yale-professors-elected-national-academy-sciences Steven Berry, Gary Brudvig, Jonathan Ellman, Leonid Glazman, and Mark Hochstrasser were elected to the academy, one of the highest honors bestowed on a U.S. scientist or engineer. Thu, 01 May 2025 17:00:00 Z https://www.hypothesisfund.org/portfolio https://www.hypothesisfund.org/portfolio Assistant Professor Moitrayee Bhattacharyya has been awarded a seed grant from the Hypothesis Fund, which supports early stage high-risk high-reward projects. With support from this award, Dr. Bhattacharyya's group will develop a "molecular scalpel" approach to isolate intact membrane contact sites for biophysical, biochemical, and structural analysis. Fri, 18 Apr 2025 12:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/protein-turnover-mapping-may-offer-clues-for-alzheimers-cancer-treatment/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/protein-turnover-mapping-may-offer-clues-for-alzheimers-cancer-treatment/ Protein turnover is essential for cellular health. Yale researchers have now determined protein turnover across several tissue types, uncovering potential targets for treating Alzheimer’s disease and cancer. Thu, 20 Mar 2025 15:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/connecticut-academy-of-science-and-engineering-elects-12-from-ysm/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/connecticut-academy-of-science-and-engineering-elects-12-from-ysm/ Twelve Yale School of Medicine faculty members are among the leading experts in science, technology, engineering, mathematics, and medicine newly elected to the Connecticut Academy of Science and Engineering. Tue, 18 Mar 2025 22:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/picciotto-elected-president-of-american-association-for-the-advancement-of-science/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/picciotto-elected-president-of-american-association-for-the-advancement-of-science/ Marina Picciotto, PhD, Charles B. G. Murphy Professor of Psychiatry and professor in the Child Study Center, of neuroscience and of pharmacology, has been elected president of the American Association for the Advancement of Science (AAAS). Fri, 07 Mar 2025 05:00:00 Z https://ventures.yale.edu/news/blavatnik-fund-innovation-yale-support-15-breakthrough-interventions-cardiometabolic https://ventures.yale.edu/news/blavatnik-fund-innovation-yale-support-15-breakthrough-interventions-cardiometabolic This year’s awardees are tackling some of the most urgent life science challenges with projects spanning novel therapeutics to AI-powered medical solutions. Fri, 28 Feb 2025 05:00:00 Z https://www.washingtonpost.com/health/2025/01/13/non-opioid-pain-pill/ https://www.washingtonpost.com/health/2025/01/13/non-opioid-pain-pill/ If successful, the drug developed by Vertex Pharmaceuticals would offer a possible alternative to potent prescription painkillers such as oxycodone, which was once heavily marketed by drug companies and fueled an epidemic of dependency and death. Mon, 13 Jan 2025 05:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/dr-joseph-contessa-on-yale-cancer-answers/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/dr-joseph-contessa-on-yale-cancer-answers/ Dr. Joseph Contessa on Yale Cancer Answers. Mon, 11 Nov 2024 05:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/peripheral-sodium-channel-blocker-could-revolutionize-treatment-for-nerve-pain/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/peripheral-sodium-channel-blocker-could-revolutionize-treatment-for-nerve-pain/ Better pain medications, known as Nav1.8 inhibitors, could be the first new drugs in decades for chronic pain conditions that don’t respond to existing treatments. Thu, 07 Nov 2024 05:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/a-promising-injectable-for-hiv-prevention-yales-onyema-ogbuagu-explains-the-research/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/a-promising-injectable-for-hiv-prevention-yales-onyema-ogbuagu-explains-the-research/ Lenacapavir could be a revolutionary tool for HIV prevention, an interim analysis shows. Thu, 03 Oct 2024 21:00:00 Z https://edition.cnn.com/2024/09/12/health/gilead-hiv-prep-lenacapavir/index.html https://edition.cnn.com/2024/09/12/health/gilead-hiv-prep-lenacapavir/index.html A drug currently used to treat HIV has also been found to dramatically reduce the risk of infection, significantly more than the primary option available for pre-exposure prophylaxis or PrEP. “The difficulty some people can experience with taking an oral pill every day, including challenges with adherence and stigma, have hindered uptake and persistence of the standard of care for too long, thus blunting PrEP’s impact on HIV prevention,” said Onyema Ogbuagu, principal investigator for the trial and director of the Yale Antivirals and Vaccines Research Program. Thu, 12 Sep 2024 04:00:00 Z https://www.asbmb.org/asbmb-today/people/082024/asbmb-names-2025-award-winners https://www.asbmb.org/asbmb-today/people/082024/asbmb-names-2025-award-winners Herbert Tabor Research Award from the ASBMB is awarded to Joseph Schlessinger. Wed, 21 Aug 2024 12:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/botanical-medicine-reduces-rectal-cancer-treatment-side-effects-that-can-sideline-surgeries/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/botanical-medicine-reduces-rectal-cancer-treatment-side-effects-that-can-sideline-surgeries/ The positive news about the botanical medicine results from a new study led by Yale Cancer Center (YCC) researchers at Yale School of Medicine (YSM) that was published in the Journal of Gastrointestinal Oncology on June 30. Fri, 09 Aug 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/yale-researchers-target-autoimmune-disease-associated-gene-variant/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/yale-researchers-target-autoimmune-disease-associated-gene-variant/ In a new study, Yale researchers identified a molecule that binds to a disease-associated macrophage migration inhibitory factor (MIF) gene variant. The discovery, they say, could lead to the development of a new generation of precision medicine-based therapies that address diverse autoimmune and inflammatory conditions. Tue, 09 Jul 2024 14:15:00 Z https://news.yale.edu/2024/05/31/well-timed-chameleon-sneaks-drug-resistant-brain-cancers https://news.yale.edu/2024/05/31/well-timed-chameleon-sneaks-drug-resistant-brain-cancers Yale scientists say KL-50, their lead “chameleon” compound, effectively targets tumors without harming healthy surrounding tissue. Fri, 31 May 2024 19:00:00 Z https://news.yale.edu/2024/05/08/getting-know-enzymes-behind-cell-communication-and-tumor-growth https://news.yale.edu/2024/05/08/getting-know-enzymes-behind-cell-communication-and-tumor-growth In the body, certain enzymes are key to cell communication and their dysfunction can lead to cancer. A new study begins to uncover how they signal and when. Wed, 08 May 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/a-better-covid-treatment-for-the-immunocompromised/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/a-better-covid-treatment-for-the-immunocompromised/ Yale scientists are working on an alternative treatment for COVID-19, for use in patients whose immune therapies clash with Paxlovid. Tue, 23 Apr 2024 17:00:00 Z https://news.yale.edu/2024/04/19/understanding-bacteria-protection-order-break-through-it https://news.yale.edu/2024/04/19/understanding-bacteria-protection-order-break-through-it Yale researchers have uncovered new details on how bacteria like E. coli build their protective barriers, which will inform new antibiotic development. Fri, 19 Apr 2024 16:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/genetic-analysis-of-rare-cervical-cancer-uncovers-potential-treatments/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/genetic-analysis-of-rare-cervical-cancer-uncovers-potential-treatments/ Yale Cancer Center researchers at Yale School of Medicine analyze the genetic landscape of 66 tumors, the largest series of cervical neuroendocrine tumors ever reported in scientific literature. Mon, 15 Apr 2024 19:05:00 Z https://medicine.yale.edu/cancer/news/breakthroughsreview/article/treatments-found-in-translational-science/ https://medicine.yale.edu/cancer/news/breakthroughsreview/article/treatments-found-in-translational-science/ Reflecting the complexities of the disease, cancer research is an ever-evolving field requiring constant infusions of innovation and funding. Starting this year, those resources at Yale Cancer Center will be augmented by its Translational Incubator, an initiative to further support and accelerate cooperation and collaboration among Yale experts. Mon, 15 Apr 2024 04:00:00 Z https://news.yale.edu/2024/03/06/sweet-stuff-how-insects-tell-sugars-apart https://news.yale.edu/2024/03/06/sweet-stuff-how-insects-tell-sugars-apart Sugar is an essential nutrient throughout the animal world. New Yale research uncovers how insects can tell different sugars apart. Wed, 06 Mar 2024 18:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/case-announces-newly-elected-members/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/case-announces-newly-elected-members/ Thirteen members of the Yale School of Medicine (YSM) and Yale School of Public Health (YSPH) faculties have been elected to the Connecticut Academy of Science and Engineering (CASE). In all, 35 of Connecticut’s leading experts in science, technology, engineering, mathematics, and medicine were elected this year. Mon, 26 Feb 2024 06:00:00 Z https://news.yale.edu/2024/01/22/rnas-do-work-outside-cells-too https://news.yale.edu/2024/01/22/rnas-do-work-outside-cells-too Scientists have been surprised in recent years to find RNAs outside of their cellular comfort zone. A Yale study offers insight into what they’re doing there. Mon, 22 Jan 2024 20:00:00 Z https://news.yale.edu/2023/12/20/using-molecular-cookie-cutters-view-membrane-protein-organization https://news.yale.edu/2023/12/20/using-molecular-cookie-cutters-view-membrane-protein-organization Protein organization is key to protein function — but difficult to uncover for membrane proteins. A new Yale-developed method overcomes the biggest challenges. Wed, 20 Dec 2023 05:00:00 Z https://websites4-live-prod.ysmdevs.com/pharm/news-article/ybdic-transforming-the-landscape-of-inclusivity-in-biological-and-biomedical-sciences-at-yale-school-of-medicine/ https://websites4-live-prod.ysmdevs.com/pharm/news-article/ybdic-transforming-the-landscape-of-inclusivity-in-biological-and-biomedical-sciences-at-yale-school-of-medicine/ At Yale School of Medicine, the Yale BBS Development and Involvement Community(YBDIC) has emerged as a catalyst for change, dedicated to fostering the intellectual and personal growth of students n the biological and biomedical sciences (BBS). Grounded in a mission driven by engagement, empowerment, outreach, and advancement, YBDIC is reshaping the landscape of inclusivity within the academic community. Wed, 13 Dec 2023 05:00:00 Z https://westcampus.yale.edu/news/yale-scientists-receive-105m-team-science-exploration-membrane-proteins-their-natural https://westcampus.yale.edu/news/yale-scientists-receive-105m-team-science-exploration-membrane-proteins-their-natural An interdisciplinary team of Yale scientists is coming together to address crucial questions about how the cell membrane environment affects membrane proteins, with support from the National Institute of General Medical Sciences (NIGMS). Wed, 28 Jun 2023 04:00:00 Z