Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications, and CBT4CBT: A randomized clinical trial in a diverse patient population

Alcohol use disorder (AUD) remains a significant contributor to preventable illness and death, particularly among racially and ethnically diverse populations. Despite hospitalization presenting a critical opportunity to initiate treatment, many patients with AUD are discharged without connecting to ongoing care. Current hospital practices often prioritize immediate medical needs, leaving the underlying disorder unaddressed and perpetuating health disparities. The most effective strategies for engaging patients in post-discharge AUD treatment—especially considering social determinants of health (SDOH) such as housing instability and medical mistrust—are not well understood. This project investigates hospital-based approaches to improve treatment engagement for AUD after discharge, comparing brief interventions, medications for AUD (MAUD), and computer-based cognitive behavioral therapy (CBT4CBT). By examining outcomes across diverse racial, ethnic, and social backgrounds, the research aims to identify scalable methods that promote equitable access to care. Results may inform hospital protocols and policy, enabling more effective, inclusive AUD treatment and helping to reduce persistent disparities in addiction outcomes.