Stuti Khandwala
she/her/hers
About
Research
Publications
2025
Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation
Luo J, Khandwala S, Hu J, Lee S, Hickey K, Levine Z, Harper J, Ting A, Weissman J. Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation. Cell 2025, 188: 5589-5604.e17. PMID: 40876456, PMCID: PMC12650760, DOI: 10.1016/j.cell.2025.08.002.Peer-Reviewed Original ResearchConceptsA-kinase anchoring protein 1Outer mitochondrial membraneProximity-specific ribosome profilingLocal translationNuclear-encoded mitochondrial genesControl of gene expressionSpatiotemporal control of gene expressionTranslation-independent mannerElectron transport chainSpatiotemporal controlMitochondrial translationMitochondrial genesCodon resolutionRibosome profilingShort proteinsLong proteinNascent chainsProtein lengthMRNA splicingSubcellular locationMitochondrial membraneCellular functionsTransport chainMonitor translationGene expression
2024
Harnessing science and technology policy to drive innovation in India: A conversation with Dr. Parvinder Maini
SHAH, A., & KHANDWALA, S. (2024). Harnessing science and technology policy to drive innovation in India: A conversation with Dr. Parvinder Maini. MIT Science Policy Review.Peer-Reviewed Original ResearchHarnessing science and technology policy to drive innovation in India: A conversation with Dr. Parvinder Maini
Shah A, Khandwala S. Harnessing science and technology policy to drive innovation in India: A conversation with Dr. Parvinder Maini. MIT Science Policy Review 2024, 5: 187-193. DOI: 10.38105/spr.4mmvhzmovi.Peer-Reviewed Original Research
2022
Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells
Lan TCT, Allan MF, Malsick LE, Woo JZ, Zhu C, Zhang F, Khandwala S, Nyeo SSY, Sun Y, Guo JU, Bathe M, Näär A, Griffiths A, Rouskin S. Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells. Nature Communications 2022, 13: 1128. PMID: 35236847, PMCID: PMC8891300, DOI: 10.1038/s41467-022-28603-2.Peer-Reviewed Original ResearchConceptsRNA genomeSARS-CoV-2 RNA genomeStructural ensemblesAlternative RNA conformationsSingle-nucleotide resolutionInfected cellsRNA biologyGenomic structureSARS-CoV-2 genomeCellular contextNucleotide resolutionFunctional characterizationGenomeRNA conformationEntire SARS-CoV-2 genomeProfiling studiesFull lengthRNAStimulation elementCellsBiologyBetacoronavirusesLittle experimental dataConformationPromotes