https://websites4-live-prod.ysmdevs.com/labmed/news-rss/?orgId=109241&title=Latest+News A selection of the latest research, academic, and other newsworthy developments at Clinical Chemistry Laboratory en-us Copyright 2026 Yale School of Medicine Thu, 14 May 2026 21:27:18 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/twenty-seven-ysm-faculty-members-recognized-for-highly-cited-research/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/twenty-seven-ysm-faculty-members-recognized-for-highly-cited-research/ Yale School of Medicine faculty members were recognized for publishing studies that rank in the top 1% based on the number of citations they received in their field. Wed, 12 Nov 2025 08:00:00 Z https://www.captodayonline.com/sample-flags-low-anion-gap-solving-lab-puzzles/ https://www.captodayonline.com/sample-flags-low-anion-gap-solving-lab-puzzles/ “There are labs using the wrong anion gap,” Dr. El-Khoury said. “There are two distributions based on different methods, one that’s much lower and one that’s higher.” And clinicians will call the laboratory to ask why an anion gap reference interval is too low or high, unaware that what they see in textbooks and online is based on other methods. “People say, ‘If it’s over 12, we should be flagging.’ No, your method is up to 17. Depending on your method,” he said, “you could have these slight shifts in electrolytes that contribute to bigger shifts in the anion gap.” The takeaways: “Problems with reference intervals can surface as a perception of low or high results among your clinicians,” he said. And IVD manufacturers do not provide reference intervals for calculated measures. “So it’s something you have to take care of” by consulting the literature to determine reference intervals for equations and calculations derived using similar methods for the individual tests. Fri, 31 Oct 2025 04:00:00 Z https://www.yahoo.com/news/us/article/a-royal-caribbean-cruise-was-just-hit-with-a-major-norovirus-outbreak-why-cruise-ships-are-a-breeding-ground-for-the-disease-175701766.html https://www.yahoo.com/news/us/article/a-royal-caribbean-cruise-was-just-hit-with-a-major-norovirus-outbreak-why-cruise-ships-are-a-breeding-ground-for-the-disease-175701766.html “Norovirus is also known as the cruise ship virus because of its frequent outbreaks on cruise ships and military bases — and it's circulating everywhere,” Dr. Craig Wilen, associate professor at the Yale School of Medicine, previously told Yahoo. “We have no drugs or vaccines for it, so it's a major public health burden.” Wed, 01 Oct 2025 04:00:00 Z https://www.selectscience.net/video/the-automated-clinical-mass-spectrometry-revolution https://www.selectscience.net/video/the-automated-clinical-mass-spectrometry-revolution Join Professor Joe El Khoury as he discusses his three areas of research including the impact of sample quality on diagnostic accuracy, the urgency of early kidney injury detection, and the evolving role of mass spectrometry in clinical labs. Learn how DART technology can accelerate toxicology workflows and hear his perspective on automation, workforce challenges, and the future of clinical efficiency. Wed, 01 Oct 2025 04:00:00 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/welcome-to-new-bids-faculty-fellows-and-staff/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/welcome-to-new-bids-faculty-fellows-and-staff/ BIDS has welcomed several new faculty, fellows, and staff to our team since October 2024. Fri, 24 Jan 2025 05:00:00 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/asci-welcomes-5-new-members-from-ysm/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/asci-welcomes-5-new-members-from-ysm/ The American Society for Clinical Investigation honors new members for translational research excellence. Tue, 14 Jan 2025 05:00:00 Z https://metabase.moreover.com/noarticleurl?type=psh&lni=6DH1-NRW1-JBNF-W2GD-00000-00 https://metabase.moreover.com/noarticleurl?type=psh&lni=6DH1-NRW1-JBNF-W2GD-00000-00 One of the most commonly prescribed drugs in the US might put users at a higher risk of an agonizing bone disease, according to new research. Mon, 25 Nov 2024 05:00:00 Z https://ventures.yale.edu/news/11-yale-projects-receive-awards-colton-center-autoimmunity https://ventures.yale.edu/news/11-yale-projects-receive-awards-colton-center-autoimmunity The Colton Center for Autoimmunity at Yale is pleased to announce the eleven 2024 Yale projects selected for their promising research in autoimmunity and allergic diseases. In addition to grant funding, Colton Center awardees receive mentorship, access to industry expertise, and feedback on their potential commercialization. Thu, 11 Jul 2024 04:00:00 Z https://www.captodayonline.com/the-race-to-keep-pace-with-drug-use-changes/ https://www.captodayonline.com/the-race-to-keep-pace-with-drug-use-changes/ Yale’s emergency department physicians alerted the clinical chemistry laboratory in mid-2023 of the need to develop testing for xylazine, a nonopiate sedative, analgesic, and muscle relaxant authorized for veterinary use. It is reported as an adulterant in illicit drug mixtures and has been detected in an increasing number of overdose deaths. Mon, 17 Jun 2024 04:00:00 Z https://www.captodayonline.com/digging-into-the-interpretation-of-tsh-results/ https://www.captodayonline.com/digging-into-the-interpretation-of-tsh-results/ In a time of wellness testing and high rates of levothyroxine prescribing for hypothyroidism, it may also be time to rethink TSH test result interpretation. Wed, 01 May 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/intrahepatic-cholestasis-of-pregnancy-icp-research-into-life-saving-diagnostics-receives-funding/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/intrahepatic-cholestasis-of-pregnancy-icp-research-into-life-saving-diagnostics-receives-funding/ Standard mass spectrometry testing for intrahepatic cholestasis of pregnancy (ICP) can take days, which is sometimes too late. A newer assay can provide test results within an hour. Thu, 04 Apr 2024 03:00:00 Z https://www.captodayonline.com/whats-going-on-interpreting-urine-toxicology-cases/ https://www.captodayonline.com/whats-going-on-interpreting-urine-toxicology-cases/ For urine toxicology screening, immunoassays are automated and rapid but have variable sensitivity and specificity and results are considered presumptive. Mass spectrometry, used for confirmation, has superior sensitivity and specificity but is labor-intensive and slow and requires significant expertise. Fri, 01 Mar 2024 05:00:00 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/yale-school-of-medicine-receives-a-dollar575000-grant-from-polybio-research-foundation-to-fund-long-covid-research/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/yale-school-of-medicine-receives-a-dollar575000-grant-from-polybio-research-foundation-to-fund-long-covid-research/ Yale's Center for Infection & Immunity, directed by Akiko Iwasaki, PhD, will lead the funded research. Thu, 22 Feb 2024 12:00:00 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/the-fdas-proposed-ruling-on-lab-tests-could-have-unintended-consequences/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/the-fdas-proposed-ruling-on-lab-tests-could-have-unintended-consequences/ Yale scientists who have developed and employed essential diagnostic tests say new regulations may needlessly hinder that process. Tue, 06 Feb 2024 19:00:00 Z https://www.selectscience.net/article/the-value-of-lc-ms-for-endocrinology-investigations-in-the-clinical-lab https://www.selectscience.net/article/the-value-of-lc-ms-for-endocrinology-investigations-in-the-clinical-lab Director of the clinical chemistry laboratory at Yale New Haven Health, Dr. Joe El-Khoury, shares how his team are developing new mass spectrometry-based methods for patient diagnostics Tue, 25 Apr 2023 04:00:00 Z https://www.medscape.com/viewarticle/991095?form=fpf https://www.medscape.com/viewarticle/991095?form=fpf Seasonal variation in one of the hormones used to monitor thyroid function could in turn lead to false diagnoses of subclinical hypothyroidism and unnecessary prescriptions of levothyroxine, says Yale clinical chemist Joe M. El-Khoury, PhD. Mon, 24 Apr 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/21-million-americans-may-take-a-hypothyroidism-drug-they-dont-need/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/21-million-americans-may-take-a-hypothyroidism-drug-they-dont-need/ A Yale expert says as many as 90% of those taking levothyroxine for an underactive thyroid may not need it, and might be harmed, largely because seasonal thyroid variations can be overlooked during diagnosis. Fri, 31 Mar 2023 04:00:00 Z https://ifcc.org/executive-board-and-council/eb-committees/awards-committe/ifcc-distinguished-awards-2023/ https://ifcc.org/executive-board-and-council/eb-committees/awards-committe/ifcc-distinguished-awards-2023/ The IFCC is pleased to announce the winners of the four IFCC Distinguished Awards. The IFCC Distinguished Awards are bestowed to laboratory medicine professionals to recognize their outstanding achievements, publicize their exceptional research and contributions to medicine and healthcare, and encourage the overall advancement of clinical chemistry and laboratory medicine. Wed, 29 Mar 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/labmed/news-article/new-class-of-drugs-could-prevent-resistant-covid-19-variants/ https://websites4-live-prod.ysmdevs.com/labmed/news-article/new-class-of-drugs-could-prevent-resistant-covid-19-variants/ Researchers have discovered that a new class of oral drugs that act directly on human cells can inhibit a diverse range of pathogenic SARS-CoV-2 strains. Wed, 08 Mar 2023 04:00:00 Z