https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-rss/?orgId=115587&title=Latest+News+from+Vaccarino+Lab A selection of the latest research, academic, and other newsworthy developments at Vaccarino Lab en-us Copyright 2026 Yale School of Medicine Sat, 16 May 2026 20:05:24 Z https://autismsciencefoundation.org/press_releases/2026-undergrad-fellowships/ https://autismsciencefoundation.org/press_releases/2026-undergrad-fellowships/ Congratulations to Ines Choi, undergraduate research assistant in the Vaccarino lab for receiving ASF’s Undergraduate Summer Research Fellowship, which supports hands-on research aimed at improving the lives of individuals with autism. Tue, 07 Apr 2026 04:00:00 Z https://news.yale.edu/2025/07/02/change-trackers-new-consortium-catalog-dna-mutations-across-human-lifetime https://news.yale.edu/2025/07/02/change-trackers-new-consortium-catalog-dna-mutations-across-human-lifetime In a multi-institution project, scientists will track genetic mutations occurring across the lifetime of 150 healthy individuals with the aim of understanding how they affect development, aging, and disease. Thu, 03 Jul 2025 18:00:00 Z https://rdcu.be/euuS5 https://rdcu.be/euuS5 Coorens, T.H.H., Oh, J.W., Choi, Y.A. et al. The Somatic Mosaicism across Human Tissues Network. Nature 643, 47–59 (2025). https://doi.org/10.1038/s41586-025-09096-7 Thu, 03 Jul 2025 04:00:00 Z https://news.yale.edu/2025/05/01/how-molecular-traffic-cops-guide-development-human-brain https://news.yale.edu/2025/05/01/how-molecular-traffic-cops-guide-development-human-brain A new Yale study offers new insight into how morphogens help regulate the development of stem cells into specialized brain cells. Thu, 01 May 2025 15:00:00 Z https://authors.elsevier.com/a/1l0yE6tu0CtjBB https://authors.elsevier.com/a/1l0yE6tu0CtjBB Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines. Scuderi S, Kang TY, Jourdon A, Nelson A, Yang L, Wu F, Anderson GM, Mariani J, Tomasini L, Sarangi V, Abyzov A, Levchenko A, Vaccarino FM. Cell Stem Cell. 2025 Apr 28; 2025 Apr 28. PMID: 40315847. Thu, 01 May 2025 04:00:00 Z https://authors.elsevier.com/a/1kxPt1S07xv72 https://authors.elsevier.com/a/1kxPt1S07xv72 Interneuron loss and microglia activation by transcriptome analyses in the basal ganglia of Tourette disorder. Wang Y, Fasching L, Wu F, Suvakov M, Huttner A, Berretta S, Roberts R, Leckman JF, Fernandez TV, Abyzov A, Vaccarino FM. Biol Psychiatry. 2025 Jan 30; 2025 Jan 30. PMID: 39892689. Tue, 15 Apr 2025 04:00:00 Z https://news.yale.edu/2025/03/11/nanowires-ai-and-bit-selective-hearing https://news.yale.edu/2025/03/11/nanowires-ai-and-bit-selective-hearing Yale researchers take a deep dive into studies about hearing, nanowire assembly, heart imaging, photosynthesis, Tourette disorder, and AI in scientific writing. Tue, 11 Mar 2025 16:00:00 Z https://www.nature.com/articles/s41586-024-08487-6 https://www.nature.com/articles/s41586-024-08487-6 A framework for neural organoids, assembloids and transplantation studies. Pașca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Novarino G, Okano H, Parmar M, Park IH, Reiner O, Song H, Studer L, Takahashi J, Temple S, Testa G, Treutlein B, Vaccarino FM, Vanderhaeghen P, Young-Pearse T. Nature. 2024 Dec 9; 2024 Dec 9. PMID: 39653126. Mon, 09 Dec 2024 05:00:00 Z https://corticaldevelopment.wordpress.com/ https://corticaldevelopment.wordpress.com/ Neural Stem Cells to Neural Circuits Giardini Naxos, Sicily, Italy - 25 May to 28 May 2025 Fri, 01 Nov 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/introducing-new-vaccarino-lab-members/ https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/introducing-new-vaccarino-lab-members/ Welcome Nagham Farah and Riya Rauthan! Fri, 01 Nov 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/vaccarino-lab-members-attend-2024-fens-conference/ https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/vaccarino-lab-members-attend-2024-fens-conference/ Federation of European Neuroscience Societies Sat, 29 Jun 2024 04:00:00 Z https://x.com/KavliAtYale/status/1797627518570398098 https://x.com/KavliAtYale/status/1797627518570398098 Congratulations to Soraya Scuderi, associate research scientist in the Vaccarino lab, for receiving a 2024 Postdoc Mentor Award! Mon, 03 Jun 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/congratulations-to-flora-vaccarino-elected-to-the-association-of-american-physicians-aap/ https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/congratulations-to-flora-vaccarino-elected-to-the-association-of-american-physicians-aap/ YCSC Harris Professor Flora Vaccarino, MD has been elected to membership in the Association of American Physicians (AAP) and will be introduced at a formal AAP dinner on Saturday, April 6, 2024 as part of the the AAP/ASCI/APSA Joint Meeting at the Swissôtel Chicago in Chicago, Illinois. Mon, 04 Mar 2024 05:00:00 Z https://site.autismadvocateparentingmagazine.com/wp-content/uploads/2024/01/Researchers_Investigate_Head_Size_and_Autism-789842.pdf https://site.autismadvocateparentingmagazine.com/wp-content/uploads/2024/01/Researchers_Investigate_Head_Size_and_Autism-789842.pdf A recent study led by Dr. Flora Vaccarino explored the different cell types in cortical organoids to gain a better understanding of the development of macrocephaly in autistic individuals. Fri, 05 Jan 2024 05:00:00 Z https://www.sfari.org/2023/11/09/two-studies-using-brain-organoids-reveal-cell-type-specific-changes-during-the-early-stages-of-human-forebrain-neuronal-development-in-autism/?mc_cid=cd7af25298 https://www.sfari.org/2023/11/09/two-studies-using-brain-organoids-reveal-cell-type-specific-changes-during-the-early-stages-of-human-forebrain-neuronal-development-in-autism/?mc_cid=cd7af25298 SFARI Investigators Flora Vaccarino at Yale University and Alexej Abyzov at Mayo Clinic used brain organoids to investigate neurobiological mechanisms linking brain size with idiopathic autism (autism without a known cause) (Jourdon et al., Nat. Neurosci., 2023). Thu, 09 Nov 2023 05:00:00 Z https://vimeo.com/showcase/10766844/video/880801464 https://vimeo.com/showcase/10766844/video/880801464 Alex Nelson (Yale Undergraduate) discusses how induced pluripotent stem cells (iPSCs) are used as a tool to better understand neurodevelopmental disorders in the Vaccarino Lab. Wed, 08 Nov 2023 05:00:00 Z https://vimeo.com/showcase/10766844/video/880811789 https://vimeo.com/showcase/10766844/video/880811789 Michael Gordon (US Marine, Yale Undergraduate) discusses his career trajectory and research using neural organoids in the Vaccarino Lab. Wed, 08 Nov 2023 05:00:00 Z https://www.spectrumnews.org/news/head-size-parts-autism-into-two-major-subtypes/ https://www.spectrumnews.org/news/head-size-parts-autism-into-two-major-subtypes/ Opposite paths in fetal brain development may explain two major subtypes of autism, a new study finds. Thu, 12 Oct 2023 04:00:00 Z https://www.ctpublic.org/news/2023-09-07/yale-researchers-find-two-types-of-autism-underscoring-the-need-for-different-treatments https://www.ctpublic.org/news/2023-09-07/yale-researchers-find-two-types-of-autism-underscoring-the-need-for-different-treatments Researchers at the Yale School of Medicine’s Child Study Center have discovered at least two different types of autism. The findings, published in the journal Nature Neuroscience, suggest a need for more than just one drug to treat symptoms. Thu, 07 Sep 2023 04:00:00 Z https://www.nhregister.com/news/article/yale-autism-study-findings-18334411.php https://www.nhregister.com/news/article/yale-autism-study-findings-18334411.php YCSC researchers comment on recent study findings indicating that Autism spectrum disorder may be associated with an imbalance of excitatory neurons in the brain, which could have implications for future treatment options. Sun, 03 Sep 2023 04:00:00 Z https://www.science.org/content/article/your-cells-don-t-have-genome-you-were-born-project-aims-chart-impact-new-mutations https://www.science.org/content/article/your-cells-don-t-have-genome-you-were-born-project-aims-chart-impact-new-mutations Every person is actually a mosaic of genomes, varying across the body and often within the same organ or tissue. Now, the National Institutes of Health (NIH) has launched a 5-year, $140 million project to map this universe of genomic diversity—and probe why it matters. Featuring YSM's Flora Vaccarino. Wed, 16 Aug 2023 04:00:00 Z https://www.healthline.com/health-news/researchers-use-mini-brains-to-look-for-origin-of-autism?utm_source=ReadNext https://www.healthline.com/health-news/researchers-use-mini-brains-to-look-for-origin-of-autism?utm_source=ReadNext A new study has highlighted an association between neurodevelopmental abnormalities and autism development. Mon, 14 Aug 2023 04:00:00 Z https://www.usnews.com/news/health-news/articles/2023-08-11/brain-organoid-study-hints-at-the-origins-of-autism https://www.usnews.com/news/health-news/articles/2023-08-11/brain-organoid-study-hints-at-the-origins-of-autism Research using three-dimensional replicas of the developing brain created in a lab dish is shedding new light on autism spectrum disorder. Fri, 11 Aug 2023 10:15:00 Z https://news.yale.edu/2023/08/10/yale-scientists-reveal-two-paths-autism-developing-brain https://news.yale.edu/2023/08/10/yale-scientists-reveal-two-paths-autism-developing-brain Two distinct abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder. The study was co-led by Alexandre Jourdon, Feinan Wu, and Jessica Mariani, all from the Kavli Institute affiliated lab of Flora Vaccarino at Yale School of Medicine. Thu, 10 Aug 2023 16:00:00 Z https://rdcu.be/djb6v https://rdcu.be/djb6v "Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis" Thu, 10 Aug 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/recognizing-ycsc-faculty-and-staff-for-long-term-service-at-yale/ https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/recognizing-ycsc-faculty-and-staff-for-long-term-service-at-yale/ Thirty-nine Yale Child Study Center community members were recognized this spring for long-term service to the University. Wed, 07 Jun 2023 04:00:00 Z https://mailchi.mp/libd/neurodevelopments-9257093 https://mailchi.mp/libd/neurodevelopments-9257093 Through the genomic sands of time Archaic genomes provide insights into human brain evolution and disease Mon, 05 Jun 2023 04:00:00 Z https://medicine.yale.edu/ysm/news/yale-medicine-magazine/article/round-up/ https://medicine.yale.edu/ysm/news/yale-medicine-magazine/article/round-up/ A collection of recent scientific findings Mon, 22 May 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/april-2023-ycsc-faculty-development-fund-awardees-announced/ https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/april-2023-ycsc-faculty-development-fund-awardees-announced/ The results of the April 2023 round of awards for the Yale Child Study Center's Clinical and Research Faculty Development Fund were announced on May 3. This annual fund supports clinical and research faculty with a primary appointment at the YCSC. The purpose is to provide start-up funds to develop research, educational, and clinical efforts that will contribute to faculty growth and development. Thu, 04 May 2023 04:00:00 Z https://academic.oup.com/nar/advance-article-abstract/doi/10.1093/nar/gkad254/7110756?utm_source=advanceaccess&utm_campaign=nar&utm_medium=email https://academic.oup.com/nar/advance-article-abstract/doi/10.1093/nar/gkad254/7110756?utm_source=advanceaccess&utm_campaign=nar&utm_medium=email "Efficient reconstruction of cell lineage trees for cell ancestry and cancer" Tue, 02 May 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/3d-organoid-models-show-brain-mechanisms-of-tourette-syndrome/ https://websites4-live-prod.ysmdevs.com/lab/vaccarino/news-article/3d-organoid-models-show-brain-mechanisms-of-tourette-syndrome/ An absence of specialized neurons in the basal ganglia of the brain appears to be key to the presence and severity of Tourette syndrome and its associated tics, a Yale study found. Thu, 12 Jan 2023 04:00:00 Z