https://websites4-live-prod.ysmdevs.com/lab/rothman/news-rss/?orgId=110148&title=Latest+News A selection of the latest research, academic, and other newsworthy developments at Rothman Lab en-us Copyright 2026 Yale School of Medicine Thu, 14 May 2026 19:06:09 Z https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/how-cells-communicate/ https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/how-cells-communicate/ Yale research uncovered how vesicles fuse and recycle, revealing core mechanisms of cellular communication. Tue, 24 Feb 2026 05:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/remembering-dr-atrouli-chatterjee/ https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/remembering-dr-atrouli-chatterjee/ It is with profound sadness that we mourn the recent passing of our dear friend and colleague, Dr. Atrouli Chatterjee. A brilliant postdoctoral associate in the Rothman Lab at Yale University's West Campus, Atrouli was a gifted scientist and an invaluable member of our community. Tue, 23 Sep 2025 04:00:00 Z https://news.yale.edu/2025/04/30/nobelist-next-door https://news.yale.edu/2025/04/30/nobelist-next-door Professors James Rothman and Joy Hirsch are both distinguished scientists and beloved resident fellows of Branford College—and hosts of monthly science-themed dinners at Mory’s.  Thu, 01 May 2025 18:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/advanced-microscopy-technique-offers-a-new-look-inside-cells/ https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/advanced-microscopy-technique-offers-a-new-look-inside-cells/ While current microscopy techniques image only a few intracellular molecules at a time, a new technique developed by Yale scientists can help researchers visualize the entire subcellular ecosystem. Tue, 09 Apr 2024 14:30:00 Z https://doi.org/10.1016/j.cell.2024.02.033 https://doi.org/10.1016/j.cell.2024.02.033 Super-resolution microscopy reveals the local distribution of proteins inside cells at the nanoscale but is in practice limited to visualizing only 2 to 3 different proteins in the same cell. FLASH-PAINT breaks this limit and empowers cell biologists to interrogate the complex spatial relationships between an essentially unlimited number of different molecules. Thu, 28 Mar 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/meet-our-speakers-dr-erin-schuman/ https://websites4-live-prod.ysmdevs.com/lab/rothman/news-article/meet-our-speakers-dr-erin-schuman/ Dr. Schuman talks about why she is inspired by neuroscience and the obstacles that she encountered along her impressive career. Fri, 16 Jun 2023 04:00:00 Z https://www.advancedsciencenews.com/visualizing-cell-membranes-using-a-plasma-membrane-on-a-chip/ https://www.advancedsciencenews.com/visualizing-cell-membranes-using-a-plasma-membrane-on-a-chip/ Scientists at Yale University have developed a "plasma membrane-on-a-chip" technology to study cell membranes more accurately. The cell membrane is crucial for cell function and is targeted by many drugs. Traditional methods have limitations, but this new silicon-based chip supports studying harvested cell membranes while maintaining lipid and protein asymmetry. Researchers can study protein and lipid behavior in these membranes, gaining insights into cell function and drug interactions. This technology has potential for advancing medicine development. Fri, 02 Dec 2022 04:00:00 Z https://www.nature.com/articles/s41592-021-01149-9 https://www.nature.com/articles/s41592-021-01149-9 Light microscopy is traditionally limited by diffraction to about 250 nm resolution in the focal plane and more than 500 nm in depth. Super-resolution STED microscopy has overcome this diffraction limit but achieving sub-100 nm super-resolution in 3D in the middle of a tissue section has been impossible due to the optical aberrations the tissue introduces into the optical beam path. Introducing adaptive optics into an isoSTED microscope, an instrument that utilizes two opposing objectives for optimal 3D resolution, allowed the authors to correct for these aberrations. Using this instrument, they were able to obtain for the first time multi-color sub-50 nm 3D resolution images in samples as complex as Drosophila egg chambers and mouse brain tissue sections. Mon, 31 May 2021 04:00:00 Z