https://websites4-live-prod.ysmdevs.com/lab/rinehart/news-rss/?orgId=115581&title=Lab+News A selection of the latest research, academic, and other newsworthy developments at Rinehart Lab en-us Copyright 2026 Yale School of Medicine Thu, 14 May 2026 19:04:43 Z https://news.yale.edu/2025/02/06/yale-scientists-recode-genome-programmable-synthetic-proteins https://news.yale.edu/2025/02/06/yale-scientists-recode-genome-programmable-synthetic-proteins A team of synthetic biologists have re-written the genetic code of an organism using a novel cellular platform for producing new classes of synthetic proteins. Thu, 06 Feb 2025 05:00:00 Z https://www.nature.com/articles/s41586-024-08501-x https://www.nature.com/articles/s41586-024-08501-x Michael Grome, a postdoctoral associate in molecular, cellular, and developmental biology at Yale and first author of the study, likened codons to three-letter words within a sentence in the genetic recipe for life. “A lot of these words are equivalent, or synonymous,” Grome said. “We set out to add more ingredients for building proteins, so we took three of these words for ‘stop’ and made them one. Two words were removed, then we re-engineered the cell so they were ‘freed’ for new function. We then engineered a cell that recognized the word to say something new, to represent a new ingredient.” Wed, 05 Feb 2025 17:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/rinehart/news-article/jesse-rinehart-joins-a-unique-nih-center-to-battle-aggressive-cancers/ https://websites4-live-prod.ysmdevs.com/lab/rinehart/news-article/jesse-rinehart-joins-a-unique-nih-center-to-battle-aggressive-cancers/ Jesse Rinehart, associate professor of cellular and molecular physiology, joins Yale University researchers to fight some of the deadliest forms of cancer with a novel approach that has gained support from the National Cancer Institute (NCI) of the National Institutes of Health (NIH). Tue, 23 Aug 2016 04:00:00 Z