https://websites4-live-prod.ysmdevs.com/lab/lusking/news-rss/?orgId=120305&title=Latest+News A selection of the latest research, academic, and other newsworthy developments at LusKing Lab en-us Copyright 2026 Yale School of Medicine Thu, 14 May 2026 19:08:34 Z https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/new-research-presented-from-yale-cancer-center-at-the-aacr-annual-meeting/ https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/new-research-presented-from-yale-cancer-center-at-the-aacr-annual-meeting/ Yale Cancer Center faculty and trainees joined over 22,000 cancer researchers from around the world to share the latest advances in cancer science and medicine earlier this week in San Diego for the 117th American Association for Cancer Research (AACR) annual meeting. Thu, 23 Apr 2026 04:00:00 Z https://ctcase.org/connecticut-academy-science-engineering-elects-36-new-members-2026/ https://ctcase.org/connecticut-academy-science-engineering-elects-36-new-members-2026/ The Connecticut Academy of Science and Engineering (CASE), announces the election of thirty-six of Connecticut’s leading experts in science, technology, engineering, mathematics, and medicine to membership in the Academy. The new members will be introduced at the Academy’s 51st Annual Dinner to be held at the Aqua Turf Club in Plantsville on May 19, 2026. Thu, 26 Mar 2026 16:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/connecticut-academy-of-science-and-engineering-elects-eight-from-ysm/ https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/connecticut-academy-of-science-and-engineering-elects-eight-from-ysm/ Eight Yale School of Medicine faculty members are among the leading experts in science, technology, engineering, mathematics, and medicine newly elected to the Connecticut Academy of Science and Engineering. Fri, 13 Mar 2026 14:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/multi-day-cancer-symposium-lays-groundwork-for-research-collaboration/ https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/multi-day-cancer-symposium-lays-groundwork-for-research-collaboration/ An intensive two-day Yale Cancer Research symposium, dedicated to advancing cancer science through innovation and strengthening partnerships between Yale University and Historically Black Colleges and Universities (HBCUs), brought together researchers from multiple disciplines this week. Tue, 07 Oct 2025 04:00:00 Z https://www.ascb.org/society-news/fourteen-visionary-scientists-named-2025-ascb-fellows/ https://www.ascb.org/society-news/fourteen-visionary-scientists-named-2025-ascb-fellows/ The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellows—a prestigious honor recognizing their exceptional contributions to cell biology and the Society. ASCB Fellows are selected by their peers and approved by the ASCB Council, celebrating a career of scientific excellence, leadership, and service… Thu, 07 Aug 2025 04:00:00 Z https://new.nsf.gov/science-matters/beyond-dna-how-scientists-are-learning-control-gene-function https://new.nsf.gov/science-matters/beyond-dna-how-scientists-are-learning-control-gene-function This article describes out work as part of the NSF EFRI Program on Chromatin Engineering. Fri, 27 Sep 2024 04:00:00 Z https://medicine.yale.edu/ysm/news/yale-medicine-magazine/article/breast-cancer-research/ https://medicine.yale.edu/ysm/news/yale-medicine-magazine/article/breast-cancer-research/ Declines in the death rate for breast cancer have furthered overall progress in cancer mortality. Wed, 20 Mar 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/albertus-magnus-cancer-research-student-science-day/ https://websites4-live-prod.ysmdevs.com/lab/lusking/news-article/albertus-magnus-cancer-research-student-science-day/ On Friday, October 28, Albertus Magnus College Professors Mark Barreuther and Rebecca Brogan brought 7 Albertus Magnus undergraduate students to Yale Cancer Center for the first Albertus Magnus Cancer Research Student Science Day. Fri, 04 Nov 2022 04:00:00 Z https://www.asbmb.org/asbmb-today/people/083122/high-affinity-binding https://www.asbmb.org/asbmb-today/people/083122/high-affinity-binding ASBMB highlights the LusKing and other jointly run laboratories. Mon, 05 Sep 2022 04:00:00 Z https://rupress.org/jcb/article-abstract/220/12/e202103030/212738/Atg39-selectively-captures-inner-nuclear-membrane?redirectedFrom=fulltext https://rupress.org/jcb/article-abstract/220/12/e202103030/212738/Atg39-selectively-captures-inner-nuclear-membrane?redirectedFrom=fulltext It is known that pathological protein aggregates can accumulate within the nucleus and can be cleared by a cytosolic autophagy machinery. However, the underlying mechanisms that allow the autophagosome to "see" aberrant proteins that are hidden by the double membrane of the nuclear envelope remains unknown. In a collaborative work, Sunandini Chandra, Philip Mannino and David Thaller provide compelling new evidence for an outside-in mechanism where a transmembrane cargo adaptor localizes at the outer nuclear membrane and reaches across the nuclear envelope lumen to capture the inner nuclear membrane into vesicles that can be ultimately captured by the autophagosome. Sun, 31 Oct 2021 04:00:00 Z https://www.biorxiv.org/content/10.1101/2021.02.07.430177v1.full https://www.biorxiv.org/content/10.1101/2021.02.07.430177v1.full DNA nanotechnology provides a versatile and powerful tool to dissect the structure-function relationship of biomolecular machines like the nuclear pore complex (NPC), an enormous protein assembly that controls molecular traffic between the nucleus and cytoplasm. To understand how the intrinsically disordered, Phe-Gly-rich nucleoporins (FG-nups) within the NPC’s central transport channel impede the diffusion of macromolecules, Yale researchers built a DNA-origami NanoTrap. The NanoTrap comprises precisely arranged FG-nups in an NPC-like channel, which sits on a baseplate that captures macromolecules that pass through the FG network. The DNA-origami based nuclear pore mimics can now trap molecules and test how FG-nups form diffusion barriers within nanopore confinement. Published in the BioRxiv, Qi Shen leading the collaboration with Chenxiang Lin (Cell Biology & Nanobiology Institute) and Patrick Lusk (Cell Biology). Mon, 08 Feb 2021 04:00:00 Z