https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-rss/?orgId=114070&title=Latest+News A selection of the latest research, academic, and other newsworthy developments at Kleinstein Lab en-us Copyright 2026 Yale School of Medicine Thu, 14 May 2026 21:30:31 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/computational-biologist-phd-student-cole-jensen-selected-for-nih-f31-award/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/computational-biologist-phd-student-cole-jensen-selected-for-nih-f31-award/ Cole Jensen, MPH, a PhD Student in Computational Biology and Bioinformatics, was recently awarded a prestigious National Institutes of Health (NIH) F31 award. Wed, 01 Apr 2026 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/researchers-uncover-a-backup-defense-system-in-the-gut/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/researchers-uncover-a-backup-defense-system-in-the-gut/ Scientists discovered an unusual method of antibody production in the gut that may help future mucosal vaccine design. Wed, 10 Dec 2025 19:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/inside-yales-cbb-phd-program-graduate-spotlights/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/inside-yales-cbb-phd-program-graduate-spotlights/ Highlighting recent graduates of Yale’s Computational Biology and Biomedical Informatics (CBB) Ph.D. Program whose cutting-edge research is driving innovation in biomedical science and data-driven discovery. Tue, 01 Jul 2025 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/new-insights-into-preterm-infant-immunity-could-inform-care/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/new-insights-into-preterm-infant-immunity-could-inform-care/ By developing new methods that extract a lot of data from a small amount of blood, Yale researchers are getting the first look at how immune systems develop in extremely preterm infants. Wed, 05 Mar 2025 19:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/yale-investigators-receive-nih-u01-award/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/yale-investigators-receive-nih-u01-award/ Yale Principal Investigators Rong Fan, PhD, Mina L. Xu, MD, Stephanie Halene, MD, and Zongming Ma, PhD, have received an NIH U01 award to establish the Center for Human Lymphoma Spatiotemporal Atlas (HuLymSTA) to construct an atlas of human lymphomas in transformation from indolent to aggressive cancer. In addition, Gisela Gabernet, PhD, Associate Research Scientist in Pathology in the Lab of Steven Kleinstein, PhD, Anthony N. Brady Professor of Pathology, received a NIH U01 grant for her project titled, “Large-scale integrated data analysis of lymphocyte receptor repertoires with workflows.” It is a three-year, $1.5M project. Thu, 05 Sep 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/new-immunology-research-reveals-potential-target-for-immune-diseases/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/new-immunology-research-reveals-potential-target-for-immune-diseases/ A gene mutation that causes human immune defects reveals new biology of antibody responses and may open the door to new autoimmune disease treatments, a Yale-led study has found. Thu, 11 Jul 2024 16:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/can-ai-help-predict-alzheimers-cancer-study-targets-telltale-immune-changes/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/can-ai-help-predict-alzheimers-cancer-study-targets-telltale-immune-changes/ The use of AI to measure immune health could lead to precision medicine tools that assess an individual’s current and future health trajectory, a Yale study finds. Thu, 11 Jul 2024 13:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/covid-19-new-omics-models-show-why-some-people-are-at-greater-risk-of-severe-disease-death/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/covid-19-new-omics-models-show-why-some-people-are-at-greater-risk-of-severe-disease-death/ One of the largest multiomics analyses to date examines hallmarks associated with COVID-19 severity and mortality, and how these factors interact with one another. Wed, 01 May 2024 19:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/yale-pathology-research-in-progress-a-rite-of-passage/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/yale-pathology-research-in-progress-a-rite-of-passage/ The Yale Pathology Research in Progress series provides students with feedback that helps improve their research projects and presentations. Mon, 25 Mar 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/peanut-allergy-may-hold-clues-to-other-food-allergies-study-finds/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/peanut-allergy-may-hold-clues-to-other-food-allergies-study-finds/ Scientists have identified a short window early in life during which an antibody that might prevent allergies to peanuts and other foods could become a therapeutic target. Fri, 09 Feb 2024 11:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/yale-pathology-graduate-students-receive-prestigious-nih-f31-awards/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/yale-pathology-graduate-students-receive-prestigious-nih-f31-awards/ Madeline Mayday, BS, and Noah Yann Lee, BS, were recently awarded prestigious Ruth L. Kirschstein Predoctoral Individual National Research Service Awards (F31) from the National Institutes of Health (NIH). Wed, 18 Oct 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/why-does-covid-19-cause-severe-illness-in-some-patients-but-not-others/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/why-does-covid-19-cause-severe-illness-in-some-patients-but-not-others/ A new study harnesses big data and bioinformatics to explore how the immune system can fight off the virus in some cases and fails in others. Fri, 09 Jun 2023 04:00:00 Z https://news.yale.edu/2022/12/05/steven-h-kleinstein-appointed-anthony-n-brady-professor-pathology https://news.yale.edu/2022/12/05/steven-h-kleinstein-appointed-anthony-n-brady-professor-pathology Kleinstein has made fundamental contributions to immunology through the development and application of innovative computational methods. Mon, 05 Dec 2022 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/researchers-probe-why-vaccine-responses-differ-from-person-to-person/ https://websites4-live-prod.ysmdevs.com/lab/kleinstein/news-article/researchers-probe-why-vaccine-responses-differ-from-person-to-person/ A team of researchers led by Yale School of Medicine’s Steven Kleinstein, PhD, is striving to understand why some people’s immune systems generate a robust protective response post-vaccination while others’ fail, and how this differs across vaccines. The team has published a series of new papers on its investigations. Mon, 31 Oct 2022 04:00:00 Z https://news.yale.edu/2022/06/29/blockchain-not-just-bitcoin-it-can-secure-and-store-genomes-too https://news.yale.edu/2022/06/29/blockchain-not-just-bitcoin-it-can-secure-and-store-genomes-too Yale researchers have found a new use for blockchain. They’ve adapted the technology to give individuals control of their own genomes. Thu, 30 Jun 2022 04:00:00 Z