Latest news from Xu Lab https://websites4-live-prod.ysmdevs.com/lab/kexu/news-rss/?orgId=119757 A selection of the latest research, academic, and other newsworthy developments at Xu Lab en-us Copyright 2026 Yale School of Medicine Fri, 15 May 2026 02:06:48 Z https://www.cell.com/iscience/fulltext/S2589-0042(25)02706-3 https://www.cell.com/iscience/fulltext/S2589-0042(25)02706-3 Combining DNA Methylation Features and Clinical Characteristics Predicts Ketamine Treatment Response for PTSD Amir Valizadeh, MD, associate research scientist, is first author of a paper in iScience that used blood DNA methylation profiles and clinical measures from a trial to predict ketamine treatment response for PTSD. Wed, 11 Feb 2026 05:00:00 Z https://link.springer.com/epdf/10.1007/s10865-024-00496-0?sharing_token=a_D21lD1Q_g2Wnyd1LANkve4RwlQNchNByi7wbcMAY4lu4tbLapLL3oQiN6PIrFThmmoMUqh-zB40U02jgrXFiHko3QivMGexeIRldPOc0P1EoySSmGaqj1Oe4X5YwhbShn5IXQeZU06i27s3UoZ6ImKj53Krv70k5rwbDf-LSc%3D https://link.springer.com/epdf/10.1007/s10865-024-00496-0?sharing_token=a_D21lD1Q_g2Wnyd1LANkve4RwlQNchNByi7wbcMAY4lu4tbLapLL3oQiN6PIrFThmmoMUqh-zB40U02jgrXFiHko3QivMGexeIRldPOc0P1EoySSmGaqj1Oe4X5YwhbShn5IXQeZU06i27s3UoZ6ImKj53Krv70k5rwbDf-LSc%3D Childhood Adversity, Accelerated GrimAge, and Associated Health Consequences Zachary Harvanek, MD, PhD, instructor of psychiatry; Ke Xu, MD, professor of psychiatry; and Rajita Sinha, PhD, Foundations Fund Professor of Psychiatry and Professor in the Child Study Center and of Neuroscience, are co-authors of a paper in Journal of Behavioral Medicine that analyzes the effects of childhood adversity on obesity, insulin resistance, and epigenetic aging. Mon, 20 May 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kexu/news-article/vayale-researchers-lead-multi-ancestry-study-of-genetics-of-problematic-alcohol-use/ https://websites4-live-prod.ysmdevs.com/lab/kexu/news-article/vayale-researchers-lead-multi-ancestry-study-of-genetics-of-problematic-alcohol-use/ VA/Yale Researchers Lead Multi-ancestry Study of Genetics of Problematic Alcohol Use A study led by VA Connecticut Healthcare Center/Yale researchers reveals ancestries around the world possess a shared genetic architecture for problematic alcohol use – habitual heavy drinking, accompanied by harmful consequences. Hang Zhou, PhD, assistant professor of psychiatry and of biomedical informatics & data science at Yale School of Medicine and VA Connecticut, and Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, and professor of genetics and of neuroscience at Yale School of Medicine and VA Connecticut, were first and senior authors, respectively. Thu, 07 Dec 2023 05:00:00 Z https://www.sciencedirect.com/science/article/pii/S2352289523000450 https://www.sciencedirect.com/science/article/pii/S2352289523000450 Greater Stress and Trauma Mediate Race-Related Differences in Epigenetic Age Between Black and White Young Adults in a Community Sample A new Yale study published in Neurobiology of Stress shows more trauma and assaults on young Black compared to white Americans is linked to faster cellular aging. Study authors are Terrell Holloway, MD; Zachary Harvanek, MD, PhD; Ke Xu, MD; Derrick Gordon, PhD; and Rajita Sinha, PhD. Mon, 24 Jul 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/kexu/news-article/yale-study-alcohol-consumption-changes-the-aging-clock/ https://websites4-live-prod.ysmdevs.com/lab/kexu/news-article/yale-study-alcohol-consumption-changes-the-aging-clock/ Alcohol Consumption Changes the Aging Clock Does alcohol drinking make you age faster? The answer is not so straightforward, based on a recently published study by researchers at Yale School of Medicine. Tue, 15 Mar 2022 04:00:00 Z