https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-rss/?orgId=118745&title=Latest+News A selection of the latest research, academic, and other newsworthy developments at Harpaz-Rotem Lab en-us Copyright 2026 Yale School of Medicine Thu, 14 May 2026 22:46:04 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/more-than-fear-a-new-profile-of-post-traumatic-stress-disorder/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/more-than-fear-a-new-profile-of-post-traumatic-stress-disorder/ Both fear and emotional pain present unique symptom profiles in individuals with post-traumatic stress disorder, potentially informing new treatment approaches, according to a new Yale study in Biological Psychiatry. Tue, 13 Jan 2026 15:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/understanding-ptsd-and-dissociation-in-wartime-direct-and-indirect-trauma-exposure/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/understanding-ptsd-and-dissociation-in-wartime-direct-and-indirect-trauma-exposure/ A new Yale-led study found that more than one-third of Israeli adults surveyed during the third month of the Israel-Hamas war suffered from probable post-traumatic stress disorder, revealing widespread psychological distress among people in Israel. Mon, 20 Oct 2025 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/yale-scientists-seek-to-uncover-neural-and-genomic-mechanisms-that-drive-anxiety/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/yale-scientists-seek-to-uncover-neural-and-genomic-mechanisms-that-drive-anxiety/ An interdisciplinary team of researchers from the Departments of Psychiatry and Neurosurgery at Yale School of Medicine has launched a pioneering study aimed at uncovering the neural and genomic mechanisms that drive anxiety. Thu, 18 Sep 2025 04:00:00 Z https://www.nytimes.com/2025/03/17/science/chatgpt-digital-therapists-anxiety.html https://www.nytimes.com/2025/03/17/science/chatgpt-digital-therapists-anxiety.html A new study in NPJ Digital Medicine found OpenAI’s artificial intelligence tool ChatGPT shows signs of anxiety when its users share “traumatic narratives” about crime, war, or car accidents. And when chatbots get stressed out, they are less likely to be useful in therapeutic settings with people. Ziv Ben-Zion, PhD, postdoctoral fellow, is the study's first author. Tue, 18 Mar 2025 04:00:00 Z https://news.yale.edu/2025/03/10/machine-learning-model-predicts-ptsd-symptom-severity-over-time https://news.yale.edu/2025/03/10/machine-learning-model-predicts-ptsd-symptom-severity-over-time Using functional brain imaging and machine learning, Yale researchers were able to predict PTSD symptoms 14 months after the initial traumatic event. Mon, 10 Mar 2025 15:00:00 Z https://psycnet.apa.org/fulltext/2024-73706-001.html https://psycnet.apa.org/fulltext/2024-73706-001.html Arielle Rubenstein, PhD, clinical psychologist at Yale School of Music, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively, of a review in APA PsycNet that aims to answer the question of whether exposure is necessary to treat posttraumatic stress disorder by integrating clinical and research literature from multiple perspectives. Tue, 23 Apr 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/harpaz-rotem-to-speak-at-sobp-symposium/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/harpaz-rotem-to-speak-at-sobp-symposium/ Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, has been invited to speak at the Neuroscience for Primetime Symposium at the Society of Biological Psychiatry (SOBP) Annual Meeting in May. Thu, 08 Feb 2024 05:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/harpaz-rotem-paper-named-2023-leading-research-achievement-by-bbrf/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/harpaz-rotem-paper-named-2023-leading-research-achievement-by-bbrf/ The paper "In PTSD, Evidence That a Single Ketamine Infusion May Enhance Extinction of Recalled Traumatic Memories" by Or Duek, PhD, assistant professor adjunct in psychiatry, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, has been named a 2023 Leading Research Achievement by the Brain & Behavior Research Foundation. Tue, 02 Jan 2024 05:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/neural-patterns-differentiate-traumatic-from-sad-autobiographical-memories-in-ptsd/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/neural-patterns-differentiate-traumatic-from-sad-autobiographical-memories-in-ptsd/ Investigators from Yale and Mount Sinai schools of medicine studied the neural activity of 28 people diagnosed with post-traumatic stress disorder (PTSD). They found that autobiographical memories for sad and neutral memories are processed differently in the brain than for traumatic memories. The findings were published in Nature Neuroscience. The co-senior author is Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology at Yale School of Medicine. Thu, 30 Nov 2023 05:00:00 Z https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(23)00227-4/fulltext https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(23)00227-4/fulltext Ian Fischer, PhD, postdoctoral fellow; Robert Pietrzak, PhD, MPH, professor of psychiatry and public health; and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are co-authors of a commentary in The Lancet Psychiatry that suggests post-traumatic stress disorder should be considered a lifetime diagnosis with remission periods. Mon, 31 Jul 2023 04:00:00 Z https://www.nature.com/articles/s41386-023-01606-3 https://www.nature.com/articles/s41386-023-01606-3 Or Duek, PhD, assistant professor adjunct of psychiatry, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively of a study published in Neuropsychopharmacology that tests the potential of a single infusion of ketamine, followed by brief exposure therapy, to enhance post-retrieval extinction of post-traumatic stress disorder trauma memories. Wed, 21 Jun 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/yale-psych-faculty-ptsd-training/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/yale-psych-faculty-ptsd-training/ A group of Yale Psychiatry researchers and clinicians recently traveled to Ukraine to ensure that their colleagues have the tools they need to care for both themselves and their patients in the wake of widespread wartime trauma. Wed, 26 Apr 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/neural-valuation-of-rewards-and-punishments-in-posttraumatic-stress-disorder-a-computational-approach/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/neural-valuation-of-rewards-and-punishments-in-posttraumatic-stress-disorder-a-computational-approach/ A new Yale study sought to unveil the neural mechanism which may govern deficits in decision making under uncertainty in posttraumatic stress disorder (PTSD). Investigators from the Yale PTSD Stress Lab, directed by Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, and the Yale Decision Neuroscience Lab, directed by Ifat Levy, PhD, associate professor and vice chair of diversity, equity and inclusion in comparative medicine, collaborated on the study, published in Translational Psychiatry. Thu, 30 Mar 2023 04:00:00 Z https://www.sciencedirect.com/science/article/abs/pii/S0022395623001164?dgcid=coauthor https://www.sciencedirect.com/science/article/abs/pii/S0022395623001164?dgcid=coauthor Five Yale researchers are authors of a study in Journal of Psychiatric Research that examines racial/ethnic differences in the prevalence of psychiatric outcomes in a population-based sample of White, Black, and Hispanic military veterans. Thu, 09 Mar 2023 04:00:00 Z https://ajpaudio.libsyn.com/website/february-2023-adversity-toxic-stress-and-racial-disparities-in-children-and-evaluating-the-evidence-for-brain-based-biotypes https://ajpaudio.libsyn.com/website/february-2023-adversity-toxic-stress-and-racial-disparities-in-children-and-evaluating-the-evidence-for-brain-based-biotypes Ziv Ben-Zion, PhD, postdoctoral associate, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively, of the paper "Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma" published in The American Journal of Psychiatry. Thu, 02 Feb 2023 04:00:00 Z https://news.yale.edu/2023/01/11/can-neuroimaging-reveal-roots-psychiatric-disorders-not-just-yet https://news.yale.edu/2023/01/11/can-neuroimaging-reveal-roots-psychiatric-disorders-not-just-yet Technology shows great promise in helping clinicians link mental health disorders to abnormal brain activity, but work remains for illnesses such as PTSD. Wed, 11 Jan 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/ben-zion-honored-by-anxiety-and-depression-association-of-america/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/ben-zion-honored-by-anxiety-and-depression-association-of-america/ Ziv Ben-Zion, PhD, a postdoctoral associate in the Yale Department of Psychiatry, has been chosen to receive the 2023 Alies Muskin Career Development Leadership Program (CDLP) Award from the Anxiety and Depression Association of America (ADAA). Thu, 15 Dec 2022 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/harpaz-rotem-to-receive-distinguished-mentorship-award-from-international-society-for-traumatic-stress-studies/ https://websites4-live-prod.ysmdevs.com/lab/harpazrotem/news-article/harpaz-rotem-to-receive-distinguished-mentorship-award-from-international-society-for-traumatic-stress-studies/ Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, has been chosen to receive the Distinguished Mentorship Award from the International Society for Traumatic Stress Studies (ISTSS). Fri, 21 Oct 2022 04:00:00 Z