https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-rss/?orgId=116145&title=Latest+News A selection of the latest research, academic, and other newsworthy developments at Caroline Johnson Lab en-us Copyright 2026 Yale School of Medicine Thu, 14 May 2026 21:12:13 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/ysph-researchers-uncover-potential-new-insights-into-colorectal-cancer-surge/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/ysph-researchers-uncover-potential-new-insights-into-colorectal-cancer-surge/ Yale School of Public Health researchers have found that reduced levels of a certain metabolite in younger cancer patients may be associated with early-onset colorectal cancer. Thu, 04 Dec 2025 05:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/two-yale-scientists-receive-2025-wham-edge-awards/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/two-yale-scientists-receive-2025-wham-edge-awards/ Last week, WHAM (Women’s Health Access Matters) announced the 10 recipients of the 2025 WHAM Edge Awards. Two Yale postdoctoral fellows, Domenica Berardi, PhD, and Na-Young Rho, PhD, have been awarded $25,000 grants for their projects investigating colorectal cancer in women and ovarian aging respectively. Mon, 24 Nov 2025 05:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/faculty-research-awards-showcase-ysph-strengths-in-science/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/faculty-research-awards-showcase-ysph-strengths-in-science/ Whether developing a new test for malaria, exposing health risks associated with climate change, or highlighting the impact of stigma on LGBTQ+ population well-being, Yale School of Public Health faculty advanced science in a variety of impactful ways over the past year. Wed, 14 May 2025 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/new-database-documents-sex-differences-in-cancer-biology-risk-factors-and-treatments/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/new-database-documents-sex-differences-in-cancer-biology-risk-factors-and-treatments/ A groundbreaking new database could lead to vast improvements in precision oncology by documenting sex-based differences in cancer treatment efficacy, biomarkers, risk factors, and microbial influences across 71 cancer types. The database — created by researchers at the Yale School of Public Health, Yale School of Medicine, and international collaborators — addresses a significant gap in current research and demonstrates how biological sex can comprehensively impact cancer onset, progression, and therapeutic outcomes. Tue, 10 Dec 2024 05:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/unraveling-the-metabolic-landscape-of-colorectal-cancer/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/unraveling-the-metabolic-landscape-of-colorectal-cancer/ A new study from the Yale School of Public Health (YSPH) offers fresh insights into our understanding of colorectal cancer (CRC) that challenge the conventional right-sided and left-sided classifications of the disease. Thu, 10 Oct 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/yale-cancer-center-experts-scientists-to-share-vision-and-research-at-leading-conference/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/yale-cancer-center-experts-scientists-to-share-vision-and-research-at-leading-conference/ Yale Cancer Center researchers will present their new cancer research findings at the 2024 AACR annual meeting. A few of the presenting YCC researchers offer their key study takeaways and the significance for patients and oncologists. Mon, 01 Apr 2024 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/yale-study-forever-chemicals-promote-cancer-cell-migration/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/yale-study-forever-chemicals-promote-cancer-cell-migration/ In a new study by researchers at the Yale School of Public Health, two “forever chemicals” spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms. Mon, 11 Dec 2023 22:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/study-reveals-colon-tumor-location-matters-for-metastatic-disease/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/study-reveals-colon-tumor-location-matters-for-metastatic-disease/ Colon cancers that spread to the liver may be substantially different depending on the location where cancerous cells originate, according to new research. Tue, 19 Sep 2023 19:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/metabolomic-research-links-diet-to-paraben-food-preservatives-in-urine-findings-important-for-women-trying-to-conceive/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/metabolomic-research-links-diet-to-paraben-food-preservatives-in-urine-findings-important-for-women-trying-to-conceive/ Yale researchers identify diet-related metabolites associated with paraben concentrations in the urine of pregnant women. Parabens can disrupt endocrine activity in the body and they have been associated with changes in fertility in women. Wed, 13 Sep 2023 18:00:00 Z https://news.yale.edu/2023/04/26/study-reveals-potential-target-precision-colorectal-cancer-treatment https://news.yale.edu/2023/04/26/study-reveals-potential-target-precision-colorectal-cancer-treatment Around 40% of colorectal cancer patients have a particular gene mutation. A new study shows it’s linked to reduced cell death and worse survival rates in men. Wed, 26 Apr 2023 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/yale-cancer-center-study-reports-racial-disparities-for-gastrointestinal-surgery/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/yale-cancer-center-study-reports-racial-disparities-for-gastrointestinal-surgery/ African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open. Mon, 04 Apr 2022 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/colorectal-cancer-and-women/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/colorectal-cancer-and-women/ Colon cancer has been undergoing a similar subdivision. Researchers have known for years that colorectal cancer is the third most common cancer diagnosis in the United States and the second leading cause of cancer-related deaths. The National Cancer Institute estimates 149,500 new cases in 2021 and 53,000 deaths. Wed, 21 Jul 2021 04:00:00 Z https://news.yale.edu/2021/07/06/sex-specific-immune-response-covid-19-linked-cellular-metabolism https://news.yale.edu/2021/07/06/sex-specific-immune-response-covid-19-linked-cellular-metabolism Researchers studying COVID-19 patients have found a metabolic pathway that is highly correlated with immune responses only in male patients, a group known to be more likely to suffer severe cases and die of the disease, representing a potential target for therapeutic intervention. Tue, 06 Jul 2021 04:00:00 Z https://www.nytimes.com/2021/07/05/well/eat/colon-cancer-soft-drinks-young-adults.html https://www.nytimes.com/2021/07/05/well/eat/colon-cancer-soft-drinks-young-adults.html Colon and rectal cancers are rising in younger adults, though researchers aren’t sure why. A new study of women and diet suggests that sugar-sweetened drinks may play a role. Mon, 05 Jul 2021 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/how-your-help-can-fund-the-next-discovery-in-womens-health-research/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/how-your-help-can-fund-the-next-discovery-in-womens-health-research/ If the challenges of the past year have taught us anything, it is that we must continue working to understand all that we can about health and disease. And when it comes to sex and gender, we should not wait for the next crisis before addressing these critical components of our health. Mon, 21 Jun 2021 04:00:00 Z https://westcampus.yale.edu/news/85m-federal-grant-aims-big-impact-small-molecules-gut https://westcampus.yale.edu/news/85m-federal-grant-aims-big-impact-small-molecules-gut Yale researchers across a range of disciplines are coming together to explore the important role of microbial metabolites in our microbiota—the trillions of bacterial cells that colonize our intestines. Mon, 07 Jun 2021 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/whry-researchers-advance-their-work-on-hiv-aids-prevention-hypoparathyroidism-and-colon-cancer/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/whry-researchers-advance-their-work-on-hiv-aids-prevention-hypoparathyroidism-and-colon-cancer/ WHRY pilot project recipients have received major competitive funding support to advance their work toward clinical applications. Mon, 05 Oct 2020 04:00:00 Z https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/deadlier-colon-cancer-develops-differently-in-women-and-men-1/ https://websites4-live-prod.ysmdevs.com/lab/cjohnson/news-article/deadlier-colon-cancer-develops-differently-in-women-and-men-1/ Researchers have found that colon cancer tumor cells produce energy for growth differently in women and men, and that this difference is associated with a more aggressive form of tumor growth with a higher incidence in women. Wed, 18 Mar 2020 04:00:00 Z https://www.nature.com/articles/s41592-019-0694-2 https://www.nature.com/articles/s41592-019-0694-2 Change is a constant in the burgeoning feld of metabolomics. That includes data analysis tools and repositories Fri, 20 Dec 2019 04:00:00 Z