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    <title>Latest news from Clinical and Translational Research Accelerator (CTRA)</title>
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    <description>A selection of the latest research, academic, and other newsworthy developments at Clinical and Translational Research Accelerator (CTRA)</description>
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    <copyright>Copyright 2026 Yale School of Medicine</copyright>
    <lastBuildDate>Fri, 15 May 2026 15:17:24 Z</lastBuildDate>
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      <title>Putting Patients at the Center of Lupus Research and Care</title>
      <description>Shivani Garg, MD, PhD, associate professor of medicine (rheumatology), director of the Lupus Clinical Research Program, and co‑director of the Yale Lupus Program, is dedicated to patient-centered lupus research and care.</description>
      <pubDate>Thu, 07 May 2026 04:00:00 Z</pubDate>
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      <title>Assessing the Risk of Heart Failure in Patients With Acute Kidney Injury</title>
      <description>When Yale School of Medicine's Sherry Mansour, MD, first began her training at Yale, she was struck by the high rates of heart failure among her patients with kidney disease.  Mansour set out to better understand the biological link between kidney injury and heart failure, aiming to identify patients at the highest risk and ensure they receive timely preventive measures, primary care follow-up, and specialist referrals. </description>
      <pubDate>Wed, 10 Sep 2025 13:00:00 Z</pubDate>
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      <title>Health Headlines: What to Know About Early-Onset Colorectal Cancer</title>
      <description>Yale School of Medicine's F. Perry Wilson, MD, discusses early-onset colorectal cancer, how women's ovulation impacts the moods of others, and a rare condition surging due to the legalization of marijuana. </description>
      <pubDate>Wed, 13 Aug 2025 04:00:00 Z</pubDate>
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      <title>Meet Melissa Shaw, Research Associate, Nephrology</title>
      <description>Meet Melissa Shaw, research associate in Yale School of Medicine's Clinical and Translation Research Accelerator, who plays a key role in the development, implementation, and oversight of various research studies.</description>
      <pubDate>Wed, 23 Jul 2025 14:56:00 Z</pubDate>
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      <title>Lu and Aklilu Honored With 2025 Dostanic Award</title>
      <description>The 2025 Iva Dostanic, MD, PhD, Physician-Scientist Trainee Award of The Department of Internal Medicine was presented to two recipients: Benjamin Y. Lu, MD, PhD, of Medical Oncology and Hematology, and Abinet M. Aklilu, MD, MPH, of Nephrology on June 26, 2025.</description>
      <pubDate>Mon, 14 Jul 2025 04:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/yale-researchers-identify-new-biomarker-panel-to-assess-risk-of-chronic-kidney-disease-progression-in-children/</link>
      <title>Yale Researchers Identify New Biomarker Panel to Assess Risk of Chronic Kidney Disease Progression in Children</title>
      <description>Yale School of Medicine researchers have identified a biomarker panel that improves the assessment of chronic kidney disease (CKD) progression in children. Their findings were published in the Journal of the American Society of Nephrology.</description>
      <pubDate>Mon, 09 Jun 2025 18:19:00 Z</pubDate>
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      <title>Novavax's COVID-19 Vaccine: Your Questions Answered</title>
      <description>The Novavax vaccine is one of three vaccines that are FDA-approved in the United States for the prevention of COVID-19. Yale Medicine answers commonly asked questions about the shot.</description>
      <pubDate>Tue, 20 May 2025 04:00:00 Z</pubDate>
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      <link>https://www.wtnh.com/news/health/virtual-reality-can-help-diagnose-adhd/</link>
      <title>Virtual Reality Can Help Diagnose ADHD</title>
      <description>Yale School of Medicine's F. Perry Wilson comments on how virtual reality could be used to diagnose ADHD.</description>
      <pubDate>Wed, 30 Apr 2025 04:00:00 Z</pubDate>
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      <title>Assessing Systemic Sclerosis With AI Deep Neural Networks</title>
      <description>In a new Yale-led study, researchers used a type of AI technology called deep neural network (DNN) analysis to decipher skin involvement and treatment response in patients with systemic sclerosis.</description>
      <pubDate>Thu, 24 Apr 2025 04:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/test-could-help-identify-patients-at-risk-severe-scleroderma/</link>
      <title>Test Could Help Identify Patients at Risk for Severe Scleroderma</title>
      <description>A new Yale study points to type 1 interferons as a potential biomarker for scleroderma patients with a worse prognosis.</description>
      <pubDate>Wed, 09 Apr 2025 15:00:00 Z</pubDate>
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      <title>Yale Researchers Use Large Language Models to Detect Gastrointestinal Bleeding</title>
      <description>A team of Yale researchers demonstrated the effectiveness of a large language model (LLM)-based pipeline in identifying overt gastrointestinal bleeding in 1,108 patients seen between 2014 and 2023 in Yale New Haven Health. The study showed a high accuracy of the model in detecting melena, hematochezia, and hematemesis, identifying recurrent bleeding, and catching more than 98% of cases. The algorithm also increased the average per-patient reimbursement.</description>
      <pubDate>Fri, 28 Feb 2025 05:00:00 Z</pubDate>
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      <link>https://www.wtnh.com/news/health/gut-bacterias-link-to-multiple-sclerosis-and-could-ozempic-help-with-alcohol-use-disorder/</link>
      <title>Gut Bacteria’s Link to Multiple Sclerosis and Could Ozempic Help With Alcohol Use Disorder?</title>
      <description>Yale's F. Perry Wilson, associate professor of medicine (nephrology) and public health (chronic disease epidemiology), discusses a link between gut bacteria and multiple sclerosis, new research on stress and cancer, and whether Ozempic could help with alcohol use disorder.</description>
      <pubDate>Wed, 19 Feb 2025 05:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/digestive-health-cme-series-2025/</link>
      <title>Digestive Health CME Series Returning for 2025</title>
      <description>The Trust Your Gut continuing medical education (CME) series is returning for 2025 to provide physicians and advanced practice providers with world-class, evidence-based digestive disease education. Each webinar will be delivered by experts across the Yale School of Medicine.</description>
      <pubDate>Mon, 06 Jan 2025 05:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/request-for-nominations-2025-iva-dostanic-award/</link>
      <title>Request for Nominations: 2025 Iva Dostanic Award</title>
      <description>Nominations are now open for the Iva Dostanic Physician-Scientist Trainee Award. The Yale Department of Medicine established an annual Physician-Scientist Trainee Award in memory of Iva Dostanic, whose intelligence, creativity, work ethic, accomplishments, and passion for the science of medicine exemplified the highest ideals of the physician-scientist.</description>
      <pubDate>Mon, 06 Jan 2025 05:00:00 Z</pubDate>
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      <title>Yale and Mila Researchers Present Their Poster at NeurIPS 2024 Annual Conference</title>
      <description>Yale and Mila Researchers at NeurIPS present Trajectory Flow Matching (TFM), a scalable and stable method for training Neural SDEs that improves clinical time series modeling and uncertainty prediction.</description>
      <pubDate>Fri, 13 Dec 2024 16:00:00 Z</pubDate>
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      <link>https://www.wfsb.com/video/2024/12/11/researchers-yale-working-with-ai-make-getting-second-opinion-easier/</link>
      <title>Researchers at Yale Working with A.I. to Make Getting a Second Opinion Easier</title>
      <description>Drs. Dennis Shung and Hua Xu recently discussed with WFSB News how, in the not-too-distant future, patients could walk into their doctor’s office and receive two expert opinions during the same visit.



</description>
      <pubDate>Wed, 11 Dec 2024 23:00:00 Z</pubDate>
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      <title>Paradigm-shifting work brought biostatistics student to YSPH</title>
      <description>This Student Spotlight focuses on Yukang Zeng, MS '25 (Biostatistics). Before coming to YSPH, he founded his own research institute and affiliated think tank.</description>
      <pubDate>Wed, 11 Dec 2024 13:00:00 Z</pubDate>
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      <link>https://www.medscape.com/viewarticle/acute-kidney-injury-really-single-disease-2024a1000kid</link>
      <title>Is Acute Kidney Injury Really a Single Disease?</title>
      <description>Acute kidney injury is being redefined as a collection of syndromes, each of which could be targeted by specific biomarkers.</description>
      <pubDate>Mon, 11 Nov 2024 05:00:00 Z</pubDate>
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      <title>Clinical Trial to Help Patients Undergoing Cancer Immunotherapy</title>
      <description>Yale School of Medicine’s Dennis Moledina, MD, has focused his scientific career on finding a biomarker to identify kidney inflammation and injury caused by a reaction to medications, also known as acute interstitial nephritis. In a new study, he hopes to use this biomarker to address acute interstitial nephritis caused by cancer immunotherapy. </description>
      <pubDate>Tue, 05 Nov 2024 13:35:00 Z</pubDate>
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      <guid isPermaLink="true">https://www.medscape.com/viewarticle/value-ai-aided-colonoscopy-advanced-neoplasia-detection-2024a1000jni</guid>
      <link>https://www.medscape.com/viewarticle/value-ai-aided-colonoscopy-advanced-neoplasia-detection-2024a1000jni</link>
      <title>Value of AI-Aided Colonoscopy on Advanced Neoplasia Detection Unclear</title>
      <description>AI-enhanced colonoscopy improves the overall detection of polyps and adenomas, but maybe not advanced neoplasia, according to a new meta-analysis. Dennis Shung, MD, PhD, discusses his new study.</description>
      <pubDate>Mon, 28 Oct 2024 04:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/new-analytics-center-cardiovascular-medicine/</link>
      <title>New Analytics Center for Cardiovascular Medicine</title>
      <description>The section of cardiovascular medicine recently established the Cardiovascular Medicine Analytics Center (CMAC). The new center provides advanced statistical support focused on the specific needs of cardiovascular medicine research.</description>
      <pubDate>Thu, 24 Oct 2024 04:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/ai-assisted-colonoscopy-research-guidelines/</link>
      <title>AI-Assisted Colonoscopy: New Research and Guidelines for Clinical Use</title>
      <description>The use of computer-aided detection (CADe) for colonoscopies has grown significantly in recent years, including at the West Haven VA. Dennis Shung, MD, PhD, is the first author of a new meta-analysis that found doctors using CADe systems found more adenomas than with standard colonoscopies. Shung is also the co-first author of new draft AGA guidelines on using AI assistance for colonoscopies.</description>
      <pubDate>Tue, 22 Oct 2024 04:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/pancreatic-cysts-james-farrell-md/</link>
      <title>Pancreatic Cysts: A Q&amp;A with James Farrell, MD</title>
      <description>James Farrell, MD, recently published a review on the current state of clinical care and research for pancreatic cysts in the New England Journal of Medicine. We spoke with him about this paper, the state of research around pancreatic cysts, and why he is inspired to learn more about this field. 
</description>
      <pubDate>Wed, 25 Sep 2024 04:00:00 Z</pubDate>
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      <link>https://websites4-live-prod.ysmdevs.com/internal-medicine/ctra/news-article/yale-database-streamlines-research-process-fosters-collaboration/</link>
      <title>Yale Database DOM-CovX Streamlines Research Process, Fosters Collaboration</title>
      <description>The COVID-19 pandemic led to a huge uptick in research across disciplines. In the first six months after the pandemic hit, 35,000 publications were indexed in PubMed; by the end of the year that number reached 90,000.</description>
      <pubDate>Tue, 24 Sep 2024 04:00:00 Z</pubDate>
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      <description>Faculty from across the Yale Department of Internal Medicine are using artificial intelligence (AI) as a tool to help improve the way they learn, teach, conduct research, and advance the field of medicine.</description>
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      <description>F. Perry Wilson, MD,  associate professor of medicine (nephrology), discusses potential predictors of Alzheimer's and multiple sclerosis, among other topics.</description>
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      <title>Greater Use of Combination Therapy Would Reduce Heart Attacks and Strokes in Patients With ASCVD, Yale Cardiologists Say</title>
      <description>By offering at least two lipid-lowering therapies up front regardless of LDL cholesterol level, physicians have the opportunity to prevent a significant number of heart attacks and strokes, the researchers write.</description>
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      <description>F. Perry Wilson, MD, associate professor of medicine (nephrology), discusses how AI will change health care.</description>
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      <title>Discoveries &amp; Impact (June 2023)</title>
      <description>Discoveries &amp; Impact highlights select scientific discoveries across the Department of Internal Medicine...</description>
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      <title>Boosting GDMT and Improving Outcomes? No Mean Task After AHF</title>
      <description>PROMPT-AHF and PACT-HF tried different approaches—EHR nudges and smarter transitional care. Success proved elusive.</description>
      <pubDate>Thu, 01 Jun 2023 04:00:00 Z</pubDate>
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      <title>New Clinical Decision Support System Benefits Patients With Acute Kidney Injury</title>
      <description>A promising new technology being evaluated in hospitals is an electronic alert system that could benefit patients suffering with acute kidney injury [AKI]. In the event of AKI, certain commonly used medications should immediately be stopped to avoid further damage. </description>
      <pubDate>Wed, 17 May 2023 04:00:00 Z</pubDate>
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      <title>Discoveries &amp; Impact (May 2023)</title>
      <description>Discoveries &amp; Impact highlights select scientific discoveries across the Department of Internal Medicine...</description>
      <pubDate>Thu, 11 May 2023 04:00:00 Z</pubDate>
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      <title>Irene Chernova is the 2023 Dostanic Award Recipient</title>
      <description>Irene Chernova, MD, PhD, instructor of medicine (nephrology) has been selected as the recipient of the 2023 Iva Dostanic, MD, PhD, Physician-Scientist Trainee Award.</description>
      <pubDate>Tue, 09 May 2023 04:00:00 Z</pubDate>
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