Tiago Paiva Prudente, MD
he/him/his
Postdoctoral AssociateAbout
Research
Publications
2026
Effect of extra virgin olive oil on mild cognitive impairment and dementia in older adults: a systematic review and meta-analysis of clinical trials
Simão V, Prudente T, De Prado Lopes Oliveira A, De Oliveira C, Silveira E. Effect of extra virgin olive oil on mild cognitive impairment and dementia in older adults: a systematic review and meta-analysis of clinical trials. Clinical Nutrition ESPEN 2026, 73: 102977. PMID: 41740793, DOI: 10.1016/j.clnesp.2026.102977.Peer-Reviewed Original ResearchMild cognitive impairmentStandardized mean differenceRandomized Controlled TrialsOlder adultsRisk of biasCochrane riskMeta-analysisGlobal cognitive function scoresSystematic reviewMini-Mental State ExaminationCochrane risk of biasAlzheimer's Disease Assessment Scale-cognitive subscaleSpectrum of mild cognitive impairmentCognitive impairmentClock Drawing TestGlobal cognitive functionCognitive function scoresQuality of evidenceCertainty of evidenceRandom-effects modelCognitive healthMini-MentalState ExaminationPooled effectAdjunctive interventionCorrelative Biomarker Analysis of PSMA Expression on CTCs and PSMA Imaging in a Phase I Study of PSMA Targeted Tubulysin Conjugate EC1169.
Zaidi S, Kuo P, Paiva Prudente T, Lacuna K, Babiker H, Aparicio R, Schonhoft J, Fernandez L, Messmann R, Groaning M, Tolcher A, Gordon M, Yoo D, Vaishampayan U, Picus J, Petrylak D, Sartor O, Morris M. Correlative Biomarker Analysis of PSMA Expression on CTCs and PSMA Imaging in a Phase I Study of PSMA Targeted Tubulysin Conjugate EC1169. Clinical Cancer Research 2026, of1-of11. PMID: 41591990, PMCID: PMC13034684, DOI: 10.1158/1078-0432.ccr-25-2313.Peer-Reviewed Original ResearchThis study investigates PSMA expression heterogeneity in metastatic prostate cancer, showing that reduced PSMA-positive circulating tumor cells correlate with longer progression-free survival despite discordant imaging results.Sleep alterations in substance use disorders: a systematic review and meta-analysis
Oliva H, Prudente T, Naveda A, Monteiro-Junior R, Potenza M, Morgan P, Angarita G. Sleep alterations in substance use disorders: a systematic review and meta-analysis. EClinicalMedicine 2026, 91: 103723. PMID: 41552000, PMCID: PMC12805338, DOI: 10.1016/j.eclinm.2025.103723.Peer-Reviewed Original ResearchSubstance use disordersUse disorderSlow-wave sleepTotal sleep timeMeta-analytical levelSystematic reviewNational Institute on Drug AbuseMeta-analysisPre-registered protocolAddictive substancesSleep abnormalitiesSleep alterationsDrug abuseSleep disturbanceWeb of ScienceSleep qualitySleep timeEligible publicationsDisordersAUDSleepCAUDNo studyAlterationsOUD
2025
Analyses of different prescriptions for health using artificial intelligence: a critical approach based on the international guidelines of health institutions
Campos V, Prudente T, Leão L, da Costa M, Oliva H, Monteiro-Junior R. Analyses of different prescriptions for health using artificial intelligence: a critical approach based on the international guidelines of health institutions. Health Information Science And Systems 2025, 13: 52. PMID: 40832454, PMCID: PMC12358344, DOI: 10.1007/s13755-025-00368-0.Peer-Reviewed Original ResearchCare planningMental healthChronic low back painLow back painInter-rater reliabilityEvidence-based guidelinesInternational guidelinesExercise counselingBack painPain domainHealth adviceGuideline concordanceInter-RaterHealth institutionsIndividualized adviceClinical guidelinesReviewer agreementNew-onset hypertensionExerciseHealthClinical vignettesCronbach's aMajor depressionBest practicesNutritionSafety of Stimulants Across Patient Populations
Oliva H, Prudente T, Mayerson T, Mignosa M, Oliva I, Potenza M, Jegede O, Angarita G. Safety of Stimulants Across Patient Populations. JAMA Network Open 2025, 8: e259492. PMID: 40343695, PMCID: PMC12065045, DOI: 10.1001/jamanetworkopen.2025.9492.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderRandomized clinical trialsAdverse eventsStimulant medicationData extractionSafety of stimulationRisk ratioIncreased riskMethodological quality assessmentPreferred Reporting ItemsPatient populationClinical conditionsDiverse patient populationsRisk of biasSafety of stimulant medicationsUnclear risk of biasTreatment of attention-deficit/hyperactivity disorderOverall AEsRandom-effects modelWeb of ScienceBinge Eating DisorderStimulant use disorderComprehensive literature searchMain OutcomesReporting ItemsRisk of Early Childhood Dental Caries Associated With Prolonged Breastfeeding: A Systematic Review and Meta‐Analysis
Lustosa K, Rodrigues L, Rocha R, Prudente T, Mezaiko E, Silva F, Silva B. Risk of Early Childhood Dental Caries Associated With Prolonged Breastfeeding: A Systematic Review and Meta‐Analysis. International Journal Of Paediatric Dentistry 2025, 35: 964-985. PMID: 40254914, PMCID: PMC12332104, DOI: 10.1111/ipd.13313.Peer-Reviewed Original ResearchEarly childhood cariesRisk of early childhood cariesProlonged breastfeedingProspective Register of Systematic ReviewsIncreased riskRisk of dental cariesEarly childhood caries prevalenceEarly childhood caries riskSystematic reviewInternational Prospective Register of Systematic ReviewsMeta-analysesRandom-effects modelChildhood cariesRisk of biasDental cariesInternational Prospective RegisterLanguage restrictionsProlonged durationObservational studyBreastfeedingEligibility criteriaMeta-analysisJBI Critical Appraisal ChecklistCritical Appraisal ChecklistMonthsTrends in the Adoption of Terminology for Oral Potentially Malignant Disorders
de Freitas Silva B, Trovão L, Mezaiko E, Prudente T, Rocha R, Santos‐Silva A, Warnakulasuriya S, Yamamoto‐Silva F. Trends in the Adoption of Terminology for Oral Potentially Malignant Disorders. Oral Diseases 2025, 31: 2672-2674. PMID: 40163625, DOI: 10.1111/odi.15332.Peer-Reviewed Original ResearchCapoeira and brain function: Hypotheses and perspectives from a systematic review
Monteiro-Junior R, da Rocha Fernandes V, Oliva H, Prudente T, Ribeiro S. Capoeira and brain function: Hypotheses and perspectives from a systematic review. Mental Health And Physical Activity 2025, 28: 100678. DOI: 10.1016/j.mhpa.2025.100678.Peer-Reviewed Original ResearchBrain functionNeurocognitive domainsNetwork of brain regionsRight dorsal premotor cortexModels of brain functionPosterior insular cortexDorsal premotor cortexPost-central gyrusBrains of individualsEmotional processingExecutive controlNeural engagementLeft hemisphereNeurocognitive effectsInsular cortexParietal cortexPrecentral gyrusSubcortical activityBrain regionsCognitive processesPremotor cortexSubcortical regionsBrain activityNeural circuitryMotor area2855 Dementia in elderly individuals with depression: a systematic review and Meta-analysis of longitudinal studies (2013–2024)
da Costa Galvão P, de Sousa Romeiro A, de Souza G, Prudente T, Dias E, Nogueira T, Silveira E. 2855 Dementia in elderly individuals with depression: a systematic review and Meta-analysis of longitudinal studies (2013–2024). Age And Ageing 2025, 54: afae277.130. DOI: 10.1093/ageing/afae277.130.Peer-Reviewed Original ResearchMild cognitive impairmentOlder adultsMeta-analysis of longitudinal studiesMeta-analysisLikelihood of older adultsSystematic reviewMini-Mental State ExaminationGeriatric Depression ScaleAssociated with higher likelihoodSymptoms of mild cognitive impairmentDepressed older adultsIdentification of risk factorsConclusion DepressionNon-depressed populationDepression ScaleMini-MentalState ExaminationDepressive symptomsTargeted interventionsI2 statisticAssess symptomsPRISMA recommendationsCohort studyDementiaStudy heterogeneityAssociations between colonization with Helicobacter pylori and risk of gastrointestinal tract cancers: An umbrella review of meta‐analyses
Prudente T, Mezaiko E, Oliva H, Yamamoto‐Silva F, de Freitas Silva B, Oliva I, Risch H. Associations between colonization with Helicobacter pylori and risk of gastrointestinal tract cancers: An umbrella review of meta‐analyses. European Journal Of Clinical Investigation 2025, 55: e14394. PMID: 39878420, DOI: 10.1111/eci.14394.Peer-Reviewed Original ResearchMeta-analysesUmbrella reviewUmbrella review of meta-analysesMeta-analyses of observational studiesHelicobacter pylori colonizationHigher quality primary studiesReview of meta-analysesCochrane Library of Systematic ReviewsAMSTAR 2 toolQuality primary studiesPrimary study overlapAssociated with EACPylori colonizationBiliary tractAssociated with biliary tractGastric cancerOesophageal squamous cell carcinomaSquamous cell carcinomaHelicobacter pyloriGI tract cancersGastrointestinal tract cancerPrimary studiesSystematic reviewCochrane LibraryObservational study