Mingyu Yang, PhD
Associate Research ScientistDownloadHi-Res Photo
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Postdoctoral Associate, School of Engineering & Applied Science
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Associate Research Scientist
Postdoctoral Associate, School of Engineering & Applied Science
Education & Training
- PhD
- Peking University, School of Life Sciences/Bioinformatics (2017)
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Mingyu Yang's published research.
Stephanie Halene, MD, Dr Med
Publications
2022
Single-Cell Transcriptomics Revealed Subtype-Specific Tumor Immune Microenvironments in Human Glioblastomas
Xiao Y, Wang Z, Zhao M, Deng Y, Yang M, Su G, Yang K, Qian C, Hu X, Liu Y, Geng L, Xiao Y, Zou Y, Tang X, Liu H, Xiao H, Fan R. Single-Cell Transcriptomics Revealed Subtype-Specific Tumor Immune Microenvironments in Human Glioblastomas. Frontiers In Immunology 2022, 13: 914236. PMID: 35669791, PMCID: PMC9163377, DOI: 10.3389/fimmu.2022.914236.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsTumor immune microenvironmentTumor-associated macrophages/microgliaImmune microenvironmentTumor cellsHuman glioblastomaMacrophages/microgliaAggressive brain tumorDifferent tumor subtypesM2-type polarizationNon-malignant cellsPoor prognosisImmune infiltrationPrimary tumorGBM patientsBrain tumorsPatient stratificationTumor subtypesMajor subtypesMalignant cellsTumor angiogenesisCell subtypesTumor microenvironmentPersonalized treatmentGBM cellsIntra-tumor heterogeneity
2020
High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue
Liu Y, Yang M, Deng Y, Su G, Enninful A, Guo CC, Tebaldi T, Zhang D, Kim D, Bai Z, Norris E, Pan A, Li J, Xiao Y, Halene S, Fan R. High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. Cell 2020, 183: 1665-1681.e18. PMID: 33188776, PMCID: PMC7736559, DOI: 10.1016/j.cell.2020.10.026.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAnimalsAutomationBrainCluster AnalysisDNA Barcoding, TaxonomicDNA, ComplementaryEmbryo, MammalianEyeFemaleGene Expression Regulation, DevelopmentalGenomicsHuman Umbilical Vein Endothelial CellsHumansMice, Inbred C57BLMicrofluidicsOrgan SpecificityReproducibility of ResultsRNA, MessengerSingle-Cell AnalysisTranscriptomeConceptsDeterministic barcodingNext-generation sequencingSingle-cell transcriptomesGene expression profilesMajor tissue typesDBiT-seqDNA barcodesDevelopmental biologyExpression profilesEarly organogenesisCancer biologyCell typesBarcodingTissue typesSequencingBarcodesBiologyRapid identificationSets of barcodesTranscriptomeParallel microfluidic channelsOrganogenesisEmbryosProteinTissue pixels
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