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INFORMATION FOR

    Leonel Rodriguez, MD, MS

    Professor of Pediatrics (Gastroenterology & Hepatology)
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    Additional Titles

    Section Chief, Pediatric Gastroenterology & Hepatology

    Director, Gastroenterology Procedure Program, Pediatrics

    About

    Titles

    Professor of Pediatrics (Gastroenterology & Hepatology)

    Section Chief, Pediatric Gastroenterology & Hepatology; Director, Gastroenterology Procedure Program, Pediatrics

    Appointments

    Other Departments & Organizations

    Education & Training

    MS
    Albert Einstein College of Medicine (2004)
    Advanced Fellow in Gastrointestinal Motility Disorders
    Montefiore Medical Center (2004)
    Postdoctoral Fellow
    Children's Hospital at Montefiore (2003)
    Resident
    Children's Hospital of Austin (2000)
    Internship
    Children's Hospital of Austin (1998)
    MD
    Francisco Marroquin University (1996)

    Research

    Overview

    One of my goals is to discover new and less invasive diagnostic tests and therapies’ aiming to improve outcomes in gastrointestinal motility disorders in children. My research is specifically oriented to gastric, small bowel and colonic motility disorders. I have been able to obtain NIH, Department of Health and Sciences, hospital, and training grants to pursue my research interests. One of my most recent papers described a novel finding of the association of anal canal relaxation with high amplitude peristaltic contractions in the colon, a new colo-anal reflex not previously described. This finding motivated an editorial in the Neurogastroenterology and Motility Journal by Dr Adil Bharucha, the Chief of Gastrointestinal Motility at the Mayo Clinic in Rochester, Minnesota, a world authority in the field (Bharucha AE. High Amplitude Propagated Contractions. Neurogastroenterol Motil 2012 Nov;24(11):977-82). I also reported for the first time the use of cyproheptadine in treating upper gastrointestinal symptoms associated to impaired gastric accommodation, a report that is changing the therapeutic standards for such symptoms. I have also contributed to the understanding of gastroparesis in children, reporting the largest study ever compiled about the outcome of such disorder in children, and furthermore, I was also the first one to describe the use of botulinum toxin for such disorder in children. I am currently studying the utility of a wireless motility capsule in gastrointestinal motility disorders in children; this device has FDA approval for its use in adults but has not been approved for use in children. I am currently working on serum and tissue biomarkers for gastrointestinal motility disorders to minimize the utilization of invasive studies in children. My work and experience has been recognized nationally and internationally, as I have been invited to lecture around the country as well as Europe, Asia and North, Central and South America.

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Leonel Rodriguez's published research.

    Publications

    2025

    2024

    Academic Achievements & Community Involvement

    Honors

    • honor

      Neurogastroenterology and Motility Basic/Translational Science Award

    • honor

      Neurogastroenterology and Motility Clinical Science Award

    Clinical Care

    Overview

    Leonel Rodriguez, MD, is chief of pediatric gastroenterology for Yale Medicine. He treats chronic and acute gastrointestinal problems in pediatric patients, and has special expertise treating problems with pediatric gastrointestinal (GI) function known as motility and functional gastrointestinal disorders.

    Dr. Rodriguez says he became interested in pediatric GI motility and functional disorders almost 20 years ago, when he saw that there were only a handful of specialists in the country. Today there are more, as well as better treatments, and diagnostic tests that are less invasive and more accurate, he says.

    Children also require a different approach than adults, he says. “In adults, this kind of care tends to be more individualized. When you treat a child, you're basically treating a family as well, so I try to incorporate families into the treatment plan so we can all work together.” Many of the GI disorders Dr. Rodriguez treats are chronic, requiring care for months and years. Families should have all essential information and know what to expect as far as tests, procedures, and medication, both short term and long term, he says.

    GI motility and functional disorders can cause difficult symptoms, including chronic constipation, vomiting, and nausea, but children should get relief, and be to go to school and be active with proper care, Dr. Rodriguez says. “I’ve seen many kids who were finally able to go back to school after they couldn't go because they were in and out of the hospital. So, there are things we can do, and most of the time it won’t be terribly invasive. It might be a simple exam and a simple evaluation, and changes to their medications or diet that can potentially have a significant impact.”

    At Yale Medicine, Dr. Rodriguez is focused on seeing pediatric patients with any type of GI motility and functional issue as quickly as possible, providing a proper evaluation, and avoiding unnecessary tests and procedures. He also provides second opinions for young patients with complex GI problems who are referred from other institutions in the U.S. and abroad.

    Clinical Specialties

    Pediatric Gastroenterology & Hepatology

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