Angela Maria Victoria-Castro, MD, MSc
Associate Research ScientistAbout
Research
Publications
2025
Diagnosing acute tubulointerstitial nephritis: novel biomarkers address an important clinical challenge
Sadarangani S, Victoria-Castro A, Moledina D. Diagnosing acute tubulointerstitial nephritis: novel biomarkers address an important clinical challenge. Current Opinion In Nephrology & Hypertension 2025, 35: 218-225. PMID: 41460039, DOI: 10.1097/mnh.0000000000001147.Peer-Reviewed Original ResearchConceptsAcute tubulointerstitial nephritisAcute kidney injuryTubulointerstitial nephritisClinical challengeEtiology of acute kidney injuryActivation normal T cellAssociated with procedural riskTumor necrosis factor-alphaNormal T-cellDiagnostic biomarkersNecrosis factor-alphaCombination of biomarkersDiagnostic workupKidney biopsyT cellsKidney injuryFactor-alphaProcedural riskAccurate biomarkersInflammatory proteinsInterleukin-9Clinical testingDiagnostic testsBiomarkersIntervention delayUtilizing perceptions of public health officials in Cali, Colombia to support the surveillance of co-circulating vector-borne diseases
Desjardins M, Casas I, Victoria-Castro A, Hammelman C, Dávalos D, Varela A, Delmelle E. Utilizing perceptions of public health officials in Cali, Colombia to support the surveillance of co-circulating vector-borne diseases. Social Science & Medicine 2025, 391: 118890. PMID: 41475302, DOI: 10.1016/j.socscimed.2025.118890.Peer-Reviewed Original ResearchConceptsPublic health officialsHealth officialsHigh-risk areasOfficials' perceptionsSemi-structured interviewsVector-borne disease managementSocioeconomic disparitiesGeographic distribution of casesParticipatory mappingEducation campaignsCommunity engagementDisease managementIntervention strategiesCommunity perspectivesUrban settingsEpidemiological dataDistribution of casesHigh riskPolitical cyclesDisease control effortsOfficialsEpidemiological surveillanceSpatial riskPerceptionHuman mobilityRespiratory Support and Mortality Risk Across the Spectrum of Cardiogenic Shock Severity
Zarif T, Caraballo C, Victoria-Castro A, Safiriyu I, Gastanadui M, Dudzinski D, Senman B, Alviar C, Tavazzi G, Elliott A, Rali A, Jacobs M, Katz J, Gage A, Miller P. Respiratory Support and Mortality Risk Across the Spectrum of Cardiogenic Shock Severity. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 104043. PMID: 41497992, PMCID: PMC12766037, DOI: 10.1016/j.jscai.2025.104043.Peer-Reviewed Original ResearchSCAI shock stageInverse probability treatment weightsInvasive mechanical ventilationIn-Hospital MortalityRespiratory supportDay of admissionCardiogenic shockTreatment weightingHospital characteristicsMortality riskDiagnosis of CSRisk-stratify patientsDemographic characteristicsSCAI stagesRisk modifiersSupport useCardiovascular AngiographyMechanical ventilationMortalityStage BPatientsAdmissionCirculatory supportSupportShock severity
2024
Promoting Collaborative Scholarship During the COVID-19 Pandemic Through an Innovative COVID-19 Data Explorer and Repository at Yale School of Medicine: Development and Usability Study
Victoria-Castro A, Arora T, Simonov M, Biswas A, Alausa J, Subair L, Gerber B, Nguyen A, Hsiao A, Hintz R, Yamamoto Y, Soufer R, Desir G, Wilson F, Villanueva M. Promoting Collaborative Scholarship During the COVID-19 Pandemic Through an Innovative COVID-19 Data Explorer and Repository at Yale School of Medicine: Development and Usability Study. JMIR Formative Research 2024, 8: e52120. PMID: 39226547, PMCID: PMC11408881, DOI: 10.2196/52120.Peer-Reviewed Original ResearchELECTRONIC ALERTS TO IMPROVE MINERALOCORTICOID RECEPTOR ANTAGONIST USE AND HYPERKALEMIA MANAGEMENT IN AMBULATORY PATIENTS WITH HEART FAILURE: A CLUSTER RANDOMIZED TRIAL
Clark K, Victoria-Castro A, Ghazi, Yamamoto Y, Coronel-Moreno C, Kadhim B, Riello R, O'Connor K, Ahmad T, Wilson F, Desai N. ELECTRONIC ALERTS TO IMPROVE MINERALOCORTICOID RECEPTOR ANTAGONIST USE AND HYPERKALEMIA MANAGEMENT IN AMBULATORY PATIENTS WITH HEART FAILURE: A CLUSTER RANDOMIZED TRIAL. Journal Of The American College Of Cardiology 2024, 83: 2395. DOI: 10.1016/s0735-1097(24)04385-7.Peer-Reviewed Original Research
2023
Rationale, Design, and Patient Characteristics of a Cluster-Randomized Pragmatic Trial to Improve Mineralocorticoid Antagonist Use
Clark K, Victoria-Castro A, Ghazi L, Yamamoto Y, Coronel-Moreno C, Kadhim B, Riello R, O'Connor K, Ahmad T, Wilson F, Desai N. Rationale, Design, and Patient Characteristics of a Cluster-Randomized Pragmatic Trial to Improve Mineralocorticoid Antagonist Use. JACC Heart Failure 2023, 12: 322-332. PMID: 37943221, DOI: 10.1016/j.jchf.2023.08.025.Peer-Reviewed Original ResearchBest practice alertMineralocorticoid receptor antagonistsNovel potassium bindersPotassium bindersEligible patientsUsual careEjection fractionSerum potassiumHistory of hyperkalemiaIncidence of hyperkalemiaStrong guideline recommendationsHeart failure hospitalizationReduced ejection fractionLaboratory test valuesPopulation health outcomesHyperkalemia treatmentMRA prescriptionAntagonist useFailure hospitalizationPatient characteristicsSecondary outcomesHeart failurePrimary outcomeGuideline recommendationsOutpatient visitsImpact of Digital Health Technology on Quality of Life in Patients With Heart Failure
Victoria-Castro A, Martin M, Yamamoto Y, Melchinger H, Weinstein J, Nguyen A, Lee K, Gerber B, Calderon F, Subair L, Lee V, Williams A, Shaw M, Arora T, Garcez A, Desai N, Ahmad T, Wilson F. Impact of Digital Health Technology on Quality of Life in Patients With Heart Failure. JACC Heart Failure 2023, 12: 336-348. PMID: 37943227, DOI: 10.1016/j.jchf.2023.09.022.Peer-Reviewed Original ResearchOverall summary scoreClinical summary scoreTotal symptom scoreKCCQ overall summary scoreUsual careHeart failureQuality of lifeMedian changeKansas City Cardiomyopathy Questionnaire overall summary scoreSummary scoresMedian agePrimary outcomeSymptom scoresPhysical functionLongitudinal carePatientsDigital health toolsLarger studyDigital health technologiesHealth toolsQoLCareDigital interventionsIndependent effectsHealth technologiesParticipant Experience with Protocol Research Kidney Biopsies in the Kidney Precision Medicine Project
Victoria-Castro A, Corona-Villalobos C, Xu A, Onul I, Huynh C, Chen S, Ugwuowo U, Sarkisova N, Dighe A, Blank K, Blanc V, Rose M, Himmelfarb J, de Boer I, Tuttle K, Roberts G, Alexandrov T, Alloway R, Alpers C, Amodu A, Anderton C, Anjani K, Appelbaum P, Ardayfio J, Arora T, Ascani H, El-Achkar T, Aulisio M, Azeloglu E, Balderes O, Balis U, Bansal S, Barasch J, Bansal S, Barkell A, Barwinska D, Basit M, Basta J, Bebiak J, Beck L, Bender F, Berglund A, Bernard L, Berrouet C, Berry B, Bjornstad P, Blanc V, Blank K, Bledsoe S, Boada P, Bogen S, Bomback A, Bonevich N, Borner K, Brown K, Bueckle A, Burg A, Burgess A, Bush L, Bush W, Campbell C, Campbell T, Canetta P, Cantley L, Caprioli R, Carson J, Chen S, Chen Y, Cheng Y, Cimino J, Colona M, Conser N, Cooperman L, Crawford D, D'Agati V, Dagher P, Daniel S, Daratha K, de Boer I, Diettman S, Dighe A, Donohoe I, Dowd F, Dunn K, Eadon M, Eddy S, Elder M, Ferkowicz M, Frey R, Gadegbeku C, Gaut J, Gilliam M, Ginley B, Gisch D, Goltsev Y, Gonzalez-Vicente A, Greka A, Grewenow S, Hacohen N, Hall D, Hansen J, Hayashi L, He C, He Y, Hedayati S, Henderson J, Hendricks A, Herlitz L, Herr B, Himmelfarb J, Hodgin J, Hoofnagle A, Hoover P, Ilori T, Iyengar R, Jain S, Jain Y, Janowczyk A, Jefferson N, Johansen C, Jolly S, Kakade V, Kellum J, Kelly K, Kermani A, Kiryluk K, Knight R, Koewler R, Kretzler M, Kudose S, Lake B, Larson B, Laszik Z, Lecker S, Lee P, Lee S, Lienczewski C, Limonte C, Lu C, Lucarelli N, Lukowski J, Luo J, Lutnick B, Ma S, Madabhushi A, Madhavan S, Maikhor S, Mariani L, Marshall J, McClelland R, McMahon G, Mehl K, Ferreira R, Menez S, Menon R, Miller R, Moe O, Moledina D, Montellano R, Mooney S, Morales M, Mukatash T, Murugan R, Nam Y, Nguyen J, Nolan G, O'toole J, Oliver G, Onul I, Otto E, Palevsky P, Palmer E, Pamreddy A, Parikh C, Parikh S, Park C, Park H, Pasa-Tolic L, Patel J, Patterson N, Phuong J, Pillai A, Pinkeney R, Poggio E, Pollack A, Prasad P, Pyle L, Quardokus E, Randhawa P, Rauchman M, Record E, Rennke H, Rezaei K, Rike A, Rivera M, Roberts G, Rosas S, Rosenberg A, Rosengart M, Rovin B, Roy N, Sabatello M, Sambandam K, Sarder P, Sarkisova N, Sarwal M, Saul J, Schaub J, Schmidt I, Sealfon R, Sedor J, Sendrey D, Shang N, Shankland S, Shapiro J, Sharma K, Sharman K, Shaw M, Shi T, Shpigel A, Sigdel T, Slade A, Snyder J, Spates-Harden K, Spraggins J, Srivastava A, Steck B, Stillman I, Stutzke C, Su J, Sun J, Sutton T, Taliercio J, Tan R, Torrealba J, Toto R, Troyanskaya O, Tublin M, Tuttle K, Ugwuowo U, Valerius M, Van de Plas R, Varela G, Vazquez M, Velickovic D, Venkatachalam M, Verma A, Victoria-Castro A, Vijayan A, Corona-Villalobos C, Vinovskis C, Viswanathan V, Vita T, Waikar S, Wang A, Wang R, Wang N, Weins A, Wen N, Wen Y, Wilcox A, Williams J, Williams K, Williams M, Wilson F, Winfree S, Winters J, Wofford S, Wong A, Woodle E, Xiong Y, Xu A, Yadati P, Ye H, Yu G, Zhang D, Zhang G, Zhang K. Participant Experience with Protocol Research Kidney Biopsies in the Kidney Precision Medicine Project. Clinical Journal Of The American Society Of Nephrology 2023, 19: 202-212. PMID: 37871973, PMCID: PMC10861112, DOI: 10.2215/cjn.0000000000000334.Peer-Reviewed Original ResearchAcute kidney injuryChronic kidney diseaseKidney Precision Medicine ProjectKidney biopsyKidney diseaseMedian levelsPrecision Medicine ProjectProtocol kidney biopsiesKidney injuryMedian ageInformed consent processMedicine ProjectHispanic ethnicityPhysical activityClinical nephrologyBiopsyBiopsy procedureFuture patientsSurvey respondentsConsent formConsent processPainTranslational Health SciencesOverall satisfactionDisease
2022
Wearables in Cardiovascular Disease
Kumar S, Victoria-Castro AM, Melchinger H, O’Connor K, Psotka M, Desai NR, Ahmad T, Wilson FP. Wearables in Cardiovascular Disease. Journal Of Cardiovascular Translational Research 2022, 16: 557-568. PMID: 36085432, DOI: 10.1007/s12265-022-10314-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPragmatic randomized trial assessing the impact of digital health technology on quality of life in patients with heart failure: Design, rationale and implementation
Victoria‐Castro A, Martin M, Yamamoto Y, Ahmad T, Arora T, Calderon F, Desai N, Gerber B, Lee KA, Jacoby D, Melchinger H, Nguyen A, Shaw M, Simonov M, Williams A, Weinstein J, Wilson FP. Pragmatic randomized trial assessing the impact of digital health technology on quality of life in patients with heart failure: Design, rationale and implementation. Clinical Cardiology 2022, 45: 839-849. PMID: 35822275, PMCID: PMC9346973, DOI: 10.1002/clc.23848.Peer-Reviewed Original ResearchConceptsQuality of lifeHF patientsYale New Haven Health SystemKansas City Cardiomyopathy QuestionnaireDigital health technologiesHeart failure careHealth technologiesDigital health interventionsDisease exacerbationHF clinicUsual carePrimary outcomeClinical outcomesHeart failurePatient engagementPatientsHealth interventionsDigital health toolsPatient empowermentHealth systemPatient usabilityHealth toolsEarly detectionFirst enrollmentHealthcare system
Academic Achievements & Community Involvement
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News
- September 24, 2024
Yale Database DOM-CovX Streamlines Research Process, Fosters Collaboration
- November 02, 2022
ASN Kidney Week 2022: Presentations from Yale Nephrology
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