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INFORMATION FOR

    Announcement

    Grants Awarded to the Department of Internal Medicine (January - March 2026)

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    Yale Department of Internal Medicine clinicians, researchers, educators, staff, and trainees received nearly $10 million in grants from January 1, 2026, to March 31, 2026, to support research.

    New Grants and Awards

    Prime PISponsor NamePrime Project TitleProject Start DateProject End DateTotal Sponsor Proj NOA Budget
    Allore, Heather GNational Institute on Aging/NIH/DHHSInterdisciplinary Infrastructure for Aging Research: Establishing the Lucidity in Alzheimer's Disease (LEAD) Network09/15/202509/14/2026$20,403
    Allore, Heather G National Institute on Aging/NIH/DHHS NIA AD/ADRD Health Care Systems Research Collaboratory 09/01/2025 08/31/2026 $327,796
    Altice, Frederick Fogarty International Center/NIH/DHHS Same-Day Antiretroviral Therapy as a Behavioral Design Intervention to Reduce Stigma in Key Affected Populations 04/01/2026 03/31/2029 $161,039
    Basu Thakur, Papia American Heart Association

    Pre-capillary Endothelial Cell Dynamics in Reversal of Pulmonary Vascular Remodeling

    01/01/2026 12/31/2027 $156,172
    Britto-Leon, Clemente J Cystic Fibrosis Foundation (CFF) Sex Differences and Transcriptional Reprogramming by CFTR Modulators in Cystic Fibrosis 02/01/2026 01/31/2027 $9,998
    Chamie, Daniel Gentuity LLC Gentuity Angio OCT Co Registration #4 12/01/2025 11/30/2030 $5,325
    Collado-Pérez, Roberto American Heart Association

    Smooth Muscle CD36 Potentially Mediates Vascular-metabolic Crosstalk

    01/01/2026 12/31/2027 $156,172
    Edelman, E. Jennifer National Institute on Drug Abuse/NIH/DHHS

    PeRsOnlized MethadOne TrEatment (PROMOTE) by implementing shared decision making

    09/30/2025 08/31/2026 $24,271
    Farhadian, Shelli F National Institute of Mental Health/NIH/DHHS

    Decoding Epigenetic Scars of Smoldering Neuroinflammation and CNS Complications In People With HIV

    03/01/2025 05/31/2026 $581,225
    Fooladi, Saba American Heart Association

    Universal iPSC-CAR-NK Cells for Treatment of Fibrotic Heart Disease

    01/01/2026 12/31/2027 $70,676
    Goldman-Israelow, Benjamin Merck

    Immunoadjuvanting saRNA Vaccines

    02/10/2026 02/09/2029 $414,768
    Jonas, Elizabeth A Eunice Kennedy Shriver National Institute of Child Health & Human Development

    ATF: Regional Specific Metabolism Regulates Specification of the Spemann Organizer

    07/01/2025 06/30/2026 $263,422
    Khera, Rohan BridgeBio Pharma, Inc.

    Development of the CarDScan ATTR-CM Mobile Application

    12/01/2025 11/30/2026 $875,366
    Khera, Rohan BridgeBio Pharma, Inc.

    ASCENT-ATTR: AI Screening and Clinician Experience with Novel Tools for ATTR Cardiomyopathy

    02/17/2026 02/16/2028 $399,301
    Koumpouras, Fotios Lupus Therapeutics

    2026 LuCIN CT Network

    01/01/2026 12/31/2027 $80,000

    Kumar, Priti

    Canadian Institutes of Health Research

    ATF Proposal: Metformin and Broadly Neutralizing Antibodies to Accelerate HIV-1 Reservoir Decay During ART

    02/01/2025 01/31/2027 $72,630

    Lansky, Alexandra J

    ReFlow Medical

    Reflow Medical Endovascular Device Meta-Analysis

    12/04/2025 12/03/2030 $36,685

    Lansky, Alexandra J

    Amplitude Vascular Systems, Inc.

    POWER CAD I - AVS Pulse Intravascular Lithotripsy™ (Pulse IVL™) to Open Vessels with Calcific Walls and Enhance Vascular Compliance and Remodeling for Coronary Artery Disease - A First-in-Human (FIH) Study

    12/04/2025 12/03/2030 $98,348

    Lansky, Alexandra J

    Merit Medical Systems, Inc.

    Merit WRAP North America SOW

    01/20/2026 01/19/2031 $508,041

    Lansky, Alexandra J

    EmStop, Inc.

    Capture 2 Biostatistics

    02/09/2026 02/08/2031 $228,419

    McConnell, Matthew

    American Liver Foundation

    Platelet-Mediated Inflammation in Primary Biliary Cholangitis

    10/01/2025 09/30/2026 $50,000

    Miner, Brienne

    National Institute on Aging/NIH/DHHS

    ATF Proposal: Pepper OAIC Coordinating Center- Apprenticeship

    06/01/2025 05/31/2026 $9,702

    Nanna, Michael

    Merck

    Efficacy of PCSK9 Inhibitor Therapy Versus Statin Monotherapy in Patients with Elevated Lipoprotein(a): A Retrospective Cohort Investigation

    01/29/2026 01/28/2028 $272,859

    O'Brien, Brendan J

    American Heart Association

    Primary Cilia Are Dynamic Regulators of Smooth Muscle Phenotype and Aortic Aneurysm

    01/01/2026 12/31/2027 $80,840

    Parise, Helen

    Merit Medical Systems, Inc.

    Merit WRAP OUS Biostatistics

    12/01/2025 11/30/2030 $127,420

    Raduwan, Hamidah

    National Institute of Allergy and Infectious Diseases/NIH/DHHS

    A Viral Vector-Based Vaccine to Induce Humoral and Cellular Immune Protection Against Powassan Virus in a Tick Transmission Model

    09/23/2025 08/31/2026 $94,897

    Schwartz, Martin A

    Leducq Foundation (formerly Fondation Leducq)

    Arteriogenesis in Translation

    12/01/2025 12/31/2030 $1,061,236

    Shulman, Gerald I

    Novo Nordisk Fonden

    ATF: Development of Novel NMR And LC/MS/MS Methods to Assess In Vivo Metabolism

    09/18/2025 12/31/2030 $935,472

    Simons, Michael

    Leducq Foundation (formerly Fondation Leducq)

    Leducq ARTIST

    01/01/2026 12/31/2030 $1,068,350

    Simons, Michael

    Coefficient Giving (formerly Open Philanthropy Project)

    Inflammation and Injury

    01/01/2026 12/31/2026 $100,000

    Somlo, Stefan

    Novartis Institute for Biomedical Research

    Unraveling the Molecular Landscapes of ADPKD: Multiomics Analysis of a Pioneering Pkd1 Re-expression Model

    12/12/2025 12/11/2027 $108,736

    Strazzabosco, Mario

    National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS

    Pathogens-Induced Biliary Inflammation In the Pathogenesis of Sclerosing Cholangiopathies

    03/01/2026 01/31/2030 $802,715

    Vilarinho, Silvia

    Mirum Pharmaceuticals Inc.

    Investigate the Utility of Whole Genome Sequencing for Diagnosis and Management of Idiopathic Cholestasis in Adults

    12/09/2025 12/09/2026 $65,481

    Vinetz, Joseph M

    National Institute of Allergy and Infectious Diseases/NIH/DHHS

    Antibody Detection for Diagnosis of Acute Leptospirosis

    09/24/2025 08/31/2026 $106,428

    Wang, Andrew

    The Brain Research Foundation

    Understanding the Role of T-lymphocytes in the Brain in Health and Disease

    01/01/2026 12/31/2027 $150,000

    Xing, Qinzhe

    American Heart Association

    Endothelialized Vascular Conduit as Arteriovenous Grafts

    01/01/2026 12/31/2027 $35,338

    Zhang, Wei

    American Heart Association

    Enhancement of Graft Patency Via Photo-Induced VEGF-Mimetic Peptide and Luminal Coating of Circulating VEGFR2+ Monocytes

    01/01/2026 12/31/2027 $159,160

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